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Bacterial pathogenesis : a subject collection from Cold Spring Harbor perspectives in medicine
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ISBN: 9781936113361 1936113368 Year: 2014 Publisher: Cold Spring Harbor (N.Y.) : Cold Spring Harbor laboratory press,

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Report to the President on combating antibiotic resistance.
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Year: 2014 Publisher: Washington, D.C. : Executive Office of the President, President's Council of Advisors on Science and Technology,

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Technological challenges in antibiotic discovery and development : a workshop summary
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ISBN: 0309298172 0309298156 Year: 2014 Publisher: Washington, District of Columbia : National Academies Press,

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"Technological Challenges in Antibiotic Discovery and Development is the summary of a workshop convened by the Chemical Sciences Roundtable in September 2013 to explore the current state of antibiotic discovery and examine the technology available to facilitate development. Through formal presentations and panel discussions, participants from academia, industry, federal research agencies discussed the technical challenges present and the incentives and disincentives industry faces in antibiotic development, and identified novel approaches to antibiotic discovery. Antibiotic resistance is a serious and growing problem in modern medicine and it is emerging as a pre-eminent public health threat. Each year in the United States alone, at least two million acquire serious infections with bacteria that are resistant to one or more antibiotics, and at least 23,000 people die annually as a direct result of these antibiotic-resistant infections. In addition to the toll on human life, antibiotic-resistant infections add considerable and avoidable costs to the already overburdened U.S. health care system. This report explores the challenges in overcoming antibiotic resistance, screening for new antibiotics, and delivering them to the sites of infection in the body. The report also discusses a path forward to develop the next generation of potent antimicrobial compounds capable of once again tilting the battle against microbial pathogens in favor of humans. Technological Challenges in Antibiotic Discovery and Development gives a broad view of the landscape of antibiotic development and the technological challenges and barriers to be overcome."--Publisher's description


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De beestjes in ons
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ISBN: 9789045027296 9045027291 Year: 2014 Publisher: Atlas Contact

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Beschrijving van het belang van lichaamseigen bacteriën voor onze gezondheid en de nadelen van het verkeerde en overmatige gebruik van antibiotica in verband daarmee. We worden dikker, zijn vaker allergisch voor bepaald voedsel, kampen met astma, hooikoorts, brandend maagzuur en prikkelbare darmen, en kinderen krijgen steeds vaker de diagnose autisme. Deze chronische ziekten zijn niet makkelijk te genezen en hebben grote invloed op de kwaliteit van ons leven. Ze zijn waarschijnlijk ontstaan doordat bepaalde soorten bacteriën, die ons al eeuwenlang beschermen tegen schadelijke invloeden, langzaam uitsterven. Volgens Martin Blaser heeft dat vooral te maken met een overmatig gebruik van antibiotica. Krijgen we deze middelen te snel voorgeschreven? Krijgen we er te veel van binnen via dierlijke producten zoals vlees, kaas, eieren en melk?


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Questions and answers: judicious use of antimicrobials in food-producing animals.
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Year: 2014 Publisher: [Riverdale, Md.] : United States Department of Agriculture, Animal and Plant Health Inspection Service,

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Low-dose antibiotics : current status and outlook for the future
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Year: 2014 Publisher: Frontiers Media SA

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Antimicrobial therapy is a key factor in our success against pathogens poised to ravage at risk or infected individuals. However, we are currently at a watershed point as we face a growing crisis of antibiotic resistance among diverse pathogens. One area of intense interest is the impact of the application of antibiotics for uses other than the treatment of patients and the association with such utilization with emerging drug resistance. This Research Topic “Low dose antibiotics: current status and outlook for the future” in Frontiers in Microbiology: Antimicrobials, Resistance and Chemotherapy details various aspects of the wide ranging effects of antimicrobial therapy from areas such as the regulation of host responses tomodulation of bacterial virulence factors to acquisition of antibiotic resistance genes.


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Low-dose antibiotics : current status and outlook for the future
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Year: 2014 Publisher: Frontiers Media SA

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Antimicrobial therapy is a key factor in our success against pathogens poised to ravage at risk or infected individuals. However, we are currently at a watershed point as we face a growing crisis of antibiotic resistance among diverse pathogens. One area of intense interest is the impact of the application of antibiotics for uses other than the treatment of patients and the association with such utilization with emerging drug resistance. This Research Topic “Low dose antibiotics: current status and outlook for the future” in Frontiers in Microbiology: Antimicrobials, Resistance and Chemotherapy details various aspects of the wide ranging effects of antimicrobial therapy from areas such as the regulation of host responses tomodulation of bacterial virulence factors to acquisition of antibiotic resistance genes.


Book
Low-dose antibiotics : current status and outlook for the future
Authors: --- --- --- --- --- et al.
Year: 2014 Publisher: Frontiers Media SA

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Antimicrobial therapy is a key factor in our success against pathogens poised to ravage at risk or infected individuals. However, we are currently at a watershed point as we face a growing crisis of antibiotic resistance among diverse pathogens. One area of intense interest is the impact of the application of antibiotics for uses other than the treatment of patients and the association with such utilization with emerging drug resistance. This Research Topic “Low dose antibiotics: current status and outlook for the future” in Frontiers in Microbiology: Antimicrobials, Resistance and Chemotherapy details various aspects of the wide ranging effects of antimicrobial therapy from areas such as the regulation of host responses tomodulation of bacterial virulence factors to acquisition of antibiotic resistance genes.


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The Richard & Hinda Rosenthal Symposium 2014 - antimicrobial resistance : a problem without borders
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ISBN: 0309312868 0309312876 0309312892 Year: 2014 Publisher: Washington, District of Columbia : The National Academies Press,

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"The Institute of Medicine launched an innovative outreach program in 1988. Through the generosity of the Rosenthal Family Foundation (formerly the Richard and Hinda Rosenthal Foundation), a discussion series was created to bring greater attention to some of the significant health policy issues facing our nation today. Each year a major health topic is addressed through remarks and conversation between experts in the field. The IOM later publishes the proceedings from this event for the benefit of a wider audience. This volume summarizes remarks by and an engaging discussion with Dr. Rima Khabbaz, Dr. Stuart Levy, Dr. Margaret (Peg) Riley, and Dr. Brad Spellberg on "Antimicrobial Resistance: A Problem Without Borders." The Centers for Disease Control and Prevention identified antimicrobial resistance as one of five urgent health threats facing the United States this year. Antimicrobial resistance is a global health security threat that will demand collaboration from many stakeholders around the world. This report highlights the crosscutting character of antimicrobial resistance and the needs for many disciplines to be brought together to be able to deal with it more effectively."--


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Antimicrobial Resistance. Global Report on Surveillance : Global Report on Surveillance
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ISBN: 9240692665 Year: 2014 Publisher: Geneva : World Health Organization,

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This WHO report produced in collaboration withMember States and other partners provides as accuratea picture as is presently possible of the magnitude ofAMR and the current state of surveillance globally.The report focuses on antibacterial resistance (ABR)in common bacterial pathogens. Why? There is amajor gap in knowledge about the magnitude of thisproblem and such information is needed to guideurgent public health actions. ABR is complex andmultidimensional. It involves a range of resistancemechanisms affecting an ever-widening range ofbacteria most of which can cause a wide spectrumof disea

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