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Inflammation --- Cellular signal transduction --- Inflammation. --- Signal Transduction. --- Cellular signal transduction. --- Inflammation. --- Pathology
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Inflammation --- Cellular signal transduction --- Inflammation. --- Signal Transduction. --- Cellular signal transduction. --- Inflammation. --- Pathology --- Pathology
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Inflammation --- Cellular signal transduction --- Inflammation. --- Signal Transduction. --- Pathology
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The Value of BCG and TNF in Autoimmunity provides an overview of current research and thinking related to tumor necrosis factor (TNF) induction and the use of the bacillus Calmette-Guérin (BCG) vaccine as potential treatment approaches to diverse forms of autoimmunity. BCG, commonly known as an anti-tuberculosis vaccine, is being explored in worldwide clinical trials as an approach to the treatment of certain forms of autoimmunity. The scope of research behind this therapeutic approach spans from the basic science of TNF signaling to research in diverse autoimmune disciplines, such
Autoimmunity. --- Tumor necrosis factor --- Autoimmune diseases --- Cellular signal transduction. --- Receptors. --- Etiology.
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"Cell Signaling presents the principles and components that underlie all known signaling mechanisms. The book provides undergraduate and graduate biology students with the tools needed to make sense of the array of specific pathways used by the cell to communicate. As each concept is explained, numerous examples derived from known signaling mechanisms are used to illustrate the key points. It describes basic signaling mechanisms such as protein interactions, changes in enzyme activity, post-translational modifications, subcellular localization of signaling molecules, and small diffusible signaling mediators. The book also explores the components of signaling pathways and how they are "wired" into pathways and circuits that can process information. The book concludes with a unique chapter that presents extended examples in which specific problems encountered in signaling are introduced and solved, followed by a chapter on methods"--
Cell interaction. --- Cellular signal transduction. --- Cellules --- Transduction du signal cellulaire --- Interaction --- Histology. Cytology --- Molecular biology --- Human medicine
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This volume generates a new paradigm for researching and understanding the biological meaning of eicosanoids. Eicosanoid is a general term for oxygenated metabolites of certain polyunsaturated fatty acids. The compounds are extremely important in human biology, in which they are well understood. Their importance to humans, however, has tended to overshadow their broader biological significance. David Stanley seeks to change that in this book, providing a general sketch of the medical background on eicosanoids and then developing a detailed critical treatment of eicosanoid actions in invertebrates and some lower vertebrates.Stanley looks at the role of eicosanoids in, for example, invertebrate reproduction, immunity, and ion transport physiology. As he explains, eicosanoids also mediate important ecological interactions, particularly host-parasite interactions. Drawing on these physiological and ecological actions, the book develops a "biological paradigm," under which we understand that eicosanoids probably exert important actions in most, if not all, animals. Because eicosanoids mediate crucial events in the lives of animals, they are endowed with unusual explanatory power. Research designed to increase our understanding of eicosanoids has thus yielded and will continue to yield important new information about animal biology. In addition to representing a major advance in our understanding of eicosanoids in animals, this book serves as an unusually comprehensive and accessible introduction to eicosanoid research in general.Originally published in 1999.The Princeton Legacy Library uses the latest print-on-demand technology to again make available previously out-of-print books from the distinguished backlist of Princeton University Press. These editions preserve the original texts of these important books while presenting them in durable paperback and hardcover editions. The goal of the Princeton Legacy Library is to vastly increase access to the rich scholarly heritage found in the thousands of books published by Princeton University Press since its founding in 1905.
Eicosanoids --- Cellular signal transduction. --- Invertebrates --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Icosanoids --- Inflammation --- Unsaturated fatty acids --- Physiological effect. --- Physiology. --- Mediators
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Plant signalling has emerged as an integrated field which has become indispensable in recent times to study any biological process. Over the last decade, an enormous amount of information has been generated in this field and the advances in information technology gave birth to bioinformatics which has helped greatly in managing the galaxy of information. It is now possible to view the different information’s in a systems biology approach which has unravelled the association/ new processes and thus helped us enormously in understanding of the biological processes. The present book is an attempt at understanding the plant signalling processes with different perspectives. Even though the plants are sessile but there exists a tremendous interconnected network of perception at morphological, physiological and molecular levels. The impact of the surrounding environment in terms of abiotic and biotic stresses is significant in terms of its survival, adaptation and productivity for the human welfare. The plants possess a wide array of processes at the organ, tissue and cellular levels which are governed by a plethora of molecules. The molecules govern individual processes and these exists a cross talk between them to form a complex network of processes. The book tries to envision how different processes are operating at different points in the life cycle of the plant.
Plant ecophysiology. --- Plant cellular signal transduction. --- Environmental plant physiology --- Physiological plant ecology --- Plant physiological ecology --- Life sciences. --- Biochemistry. --- Plant biochemistry. --- Proteins. --- Cytokines. --- Growth factors. --- Plant science. --- Botany. --- Life Sciences. --- Plant Biochemistry. --- Plant Sciences. --- Cytokines and Growth Factors. --- Receptors. --- Biochemistry, general. --- Protein Science. --- Cellular signal transduction --- Plant cellular control mechanisms --- Ecophysiology --- Plant ecology --- Plant physiology --- Cell receptors. --- Cell membrane receptors --- Cell surface receptors --- Receptors, Cell --- Binding sites (Biochemistry) --- Cell membranes --- Proteins --- Cellular immunity --- Immune response --- Botanical science --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Biology --- Natural history --- Plants --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Regulation --- Composition --- Proteins . --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Cell growth factors --- Cellular growth factors --- Growth peptides --- Growth promoting substances --- Growth substances --- Peptide growth factors --- Peptide regulatory factors --- Polypeptide growth factors --- Cytokines --- Peptides --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Botany --- Phytochemicals --- Plant biochemical genetics --- Floristic botany
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This book presents the most up-to-date information in the area of targeted therapeutics with a particular focus on pathway-centered approaches and transcription by leading authorities in molecular cancer research. The goal is to cover several critical principles of cancer therapeutics, ranging from regulation of cancer associated genes by coregulators, cancer cell signaling, modifiers of epigenome functionality and specific protein domains, and emerging significance of splicing. The book is directed for basic and translational scientists, clinicians, clinical investigators, fellows, residents, graduate students, and educators in the areas of molecular therapeutics and cancer medicine, and medical sciences at-large. Readers will be able to grasp the overall importance of the pathway, associated pathobiology and clinical manifestation, and possible points of intervention with a goal to solidify new cancer therapeutic targets.
Transcription factors --- Cancer --- Diseases --- Biological Science Disciplines --- Biochemical Processes --- Gene Expression --- Biology --- Cell Physiological Processes --- Natural Science Disciplines --- Chemical Processes --- Cell Physiological Phenomena --- Genetic Processes --- Biochemical Phenomena --- Chemical Phenomena --- Genetic Phenomena --- Phenomena and Processes --- Disciplines and Occupations --- Physiology --- Transcription, Genetic --- Signal Transduction --- Neoplasms --- Genetics --- Medicine --- Health & Biological Sciences --- Oncology --- Genetic aspects --- Treatment --- Cellular signal transduction. --- Molecular aspects. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Oncology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Physiological effect
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Plant innate immunity is a potential surveillance system of plants and is the first line of defense against invading pathogens. The immune system is a sleeping system in unstressed healthy plants and is activated on perception of the pathogen-associated molecular patterns (PAMP; the pathogen’s signature) of invading pathogens. The PAMP alarm/danger signals are perceived by plant pattern-recognition receptors (PRRs). The plant immune system uses several second messengers to encode information generated by the PAMPs and deliver the information downstream of PRRs to proteins which decode/interpret signals and initiate defense gene expression. Activation of the ‘sleeping’ plant innate immune system by using different biotechnological tools would suppress the development of a wide range of plant pathogens in economically important crop plants. Enhancement of disease resistance through altered regulation of plant immunity signaling systems would be a durable and publicly acceptable technology in plant disease management. This book describes the most fascinating PAMP-PRR signaling complex and signal transduction systems. It also discusses the highly complex networks of signaling pathways involved in transmission of the signals to induce distinctly different defense-related genes to mount offence against different biotrophic, hemibiotrophic, and necrotrophic pathogens.
Plant immunology. --- Molecular immunology. --- Immune system --- Immunity --- Immunology, Plant --- Molecular aspects --- Life sciences. --- Biotechnology. --- Agriculture. --- Microbiology. --- Plant pathology. --- Plant physiology. --- Life Sciences. --- Plant Pathology. --- Plant Physiology. --- Immunology --- Plants --- Molecular biology --- Disease and pest resistance --- Plant diseases. --- Farming --- Husbandry --- Industrial arts --- Life sciences --- Food supply --- Land use, Rural --- Chemical engineering --- Genetic engineering --- Microbial biology --- Biology --- Microorganisms --- Botany --- Physiology --- Communicable diseases in plants --- Crop diseases --- Crops --- Diseases of plants --- Microbial diseases in plants --- Pathological botany --- Pathology, Vegetable --- Phytopathology --- Plant pathology --- Vegetable pathology --- Agricultural pests --- Crop losses --- Diseased plants --- Phytopathogenic microorganisms --- Plant pathologists --- Plant quarantine --- Pathology --- Diseases and pests --- Diseases --- Wounds and injuries --- Plant cellular signal transduction. --- Disease and pest resistance.
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