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Cancer --- Cellular signal transduction. --- Cancer genes. --- Genetic regulation. --- Neoplasms --- Signal Transduction. --- Gene Expression. --- Gene expression --- Gene expression regulation --- Gene regulation --- Biosynthesis --- Cellular control mechanisms --- Molecular genetics --- Genes --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Information theory in biology --- Cancer genetics --- Cancer genes --- Expression, Gene --- Expressions, Gene --- Gene Expressions --- Gene Expression Profiling --- Receptor Mediated Signal Transduction --- Signal Transduction Pathways --- Signal Transduction Systems --- Cell Signaling --- Receptor-Mediated Signal Transduction --- Signal Pathways --- Pathway, Signal --- Pathway, Signal Transduction --- Pathways, Signal --- Pathways, Signal Transduction --- Receptor-Mediated Signal Transductions --- Signal Pathway --- Signal Transduction Pathway --- Signal Transduction System --- Signal Transduction, Receptor-Mediated --- Signal Transductions --- Signal Transductions, Receptor-Mediated --- System, Signal Transduction --- Systems, Signal Transduction --- Transduction, Signal --- Transductions, Signal --- Cell Communication --- Receptor-CD3 Complex, Antigen, T-Cell --- Receptor Cross-Talk --- Feedback, Physiological --- Gasotransmitters --- Genetic aspects. --- Molecular aspects. --- genetics. --- Regulation --- Genetic aspects

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Sphingolipids are lipid components of the plasma membrane of eukaryotic cells with an important function in signaling mechanisms in the cell. This  book provides insight into the physiological and pathophysiological role of sphingolipids and in particular its derivative ceramide. The function of Sphingolipids in cell signaling with regard to infectious and lung diseases, cancer, cardiovascular diseases and neuropsychiatric disorders are described and treated in distinct parts. Together with Volume 215 from the same Editors, the collection represents a unique, comprehensive work on Sphingolipids, providing information on both: Sphingolipid basic biology  as well as its important function in a (patho)physiological context. The book is written for scientists in pharmacology, biochemistry and cell biology with a focus on biomedical research as well as for clinicians in pharmacology, oncology, cardiology, neurology and infectious disease.   .

Sphingolipids. --- Sphingolipids --- Cellular signal transduction. --- Pathophysiology. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Lipids --- Sphingosine --- Toxicology. --- Cardiology. --- Oncology. --- Immunology. --- Neurosciences. --- Lipids. --- Pharmacology/Toxicology. --- Cancer Research. --- Lipidology. --- Lipides --- Lipins --- Lipoids --- Biomolecules --- Steroids --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Immunobiology --- Life sciences --- Serology --- Tumors --- Heart --- Internal medicine --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Diseases --- Toxicology --- Pharmacology. --- Cancer research. --- Cancer research --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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Our view of plants is changing dramatically. Rather than being only slowly responding organisms, their signaling is often very fast and signals, both of endogenous and exogenous origin, spread throughout plant bodies rapidly. Higher plants coordinate and integrate their tissues and organs via sophisticated sensory systems, which sensitively screen both internal and external factors, feeding them information through both chemical and electrical systemic long-distance communication channels. This revolution in our understanding of higher plants started some twenty years ago with the discovery of systemin and rapid advances continue to be made. This volume captures the current ‘state of the art’ of this exciting topic in plant sciences.

Botany --- Earth & Environmental Sciences --- Plant Physiology --- Plant cellular signal transduction. --- Cellular signal transduction. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Life sciences. --- Plant biochemistry. --- Plant genetics. --- Plant pathology. --- Plant physiology. --- Life Sciences. --- Plant Physiology. --- Plant Biochemistry. --- Plant Genetics & Genomics. --- Plant Pathology. --- Plants --- Physiology --- Communicable diseases in plants --- Crop diseases --- Crops --- Diseases of plants --- Microbial diseases in plants --- Pathological botany --- Pathology, Vegetable --- Phytopathology --- Plant pathology --- Vegetable pathology --- Agricultural pests --- Crop losses --- Diseased plants --- Phytopathogenic microorganisms --- Plant pathologists --- Plant quarantine --- Genetics --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Phytochemicals --- Plant biochemical genetics --- Biosciences --- Sciences, Life --- Science --- Pathology --- Diseases and pests --- Diseases --- Wounds and injuries --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Cellular signal transduction --- Plant cellular control mechanisms --- Biochemistry. --- Plant diseases. --- Plant Genetics and Genomics. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Composition

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Molecular Beacons explains working principle of molecular beacons, discusses their design, synthesis, purification and characterization, explores their thermodynamic and kinetic properties, and more importantly, reviews their in vivo and in vitro applications with the emphasis on the design and modification of molecular beacons for in vivo mRNA imaging applications. This book is designed to bring together in a single resource an organized and comprehensive view of molecular beacons and will be a valuable resource for academic, clinical and industrial scientists and graduate students who may consider exploring molecular beacons in their research or practice. Chaoyong James Yang is the Lu Jiaxi Professor of Chemistry at Xiamen University, China. Weihong Tan is a Distinguished Professor of Chemistry and Biomedical Engineering at Hunan University, China and also a University of Florida Distinguished Professor and V. T. and Louis Jackson Professor of Chemistry at the University of Florida, USA.

Mechanical Engineering --- Engineering & Applied Sciences --- Bioengineering --- Molecular biology. --- Cellular signal transduction. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Molecular biochemistry --- Molecular biophysics --- Chemistry. --- Gene expression. --- Analytical chemistry. --- Biotechnology. --- Nucleic acids. --- Cell biology. --- Gene Expression. --- Nucleic Acid Chemistry. --- Cell Biology. --- Analytical Chemistry. --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Cytology. --- Analytical biochemistry. --- Analytic biochemistry --- Chemistry, Analytic --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Polynucleotides --- Genes --- Genetic regulation --- Chemical engineering --- Genetic engineering --- Expression --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry --- Molecular probes. --- Nucleic acid probes.

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The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorgenesis. This volume presents virtually all aspects of tumor biology because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Rho, Wnt, TGFbeta and p53. Hippo signaling is not solely involved in regulating “classic” tumor characteristics such as cell proliferation, survival and growth, but is also diversely involved in cell-autonomous and non-cell-autonomous differentiation, migration and organ size control. With the multitude of signaling events mediated by the Hippo pathway and the vastly different functions that it plays, it is evident that these tumor suppressors are unique governors of cellular homeostasis. This timely volume gathers wide-ranging and burgeoning information on the Hippo pathway and its role in cancer into an accessible format of a single book.With the multitude of signaling events mediated by the Hippo pathway and the vastly different functions that it plays, it is evident that these tumor suppressors are unique governors of cellular homeostasis. This timely volume gathers wide-ranging and burgeoning information on the Hippo pathway and its role in cancer into an accessible format of a single book.

Cancer -- Genetic aspects. --- Cancer -- Molecular aspects. --- Cellular signal transduction. --- Oncology. --- Cancer --- Neoplastic Processes --- Peptides --- Protein Kinases --- Neoplasms --- Phosphotransferases (Alcohol Group Acceptor) --- Amino Acids, Peptides, and Proteins --- Diseases --- Chemicals and Drugs --- Phosphotransferases --- Transferases --- Enzymes --- Enzymes and Coenzymes --- Intracellular Signaling Peptides and Proteins --- Protein-Serine-Threonine Kinases --- Cell Transformation, Neoplastic --- Medicine --- Health & Biological Sciences --- Oncology --- Genetic aspects --- Genetic aspects. --- Molecular aspects. --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Cancer genetics --- Medicine. --- Cancer research. --- Medical microbiology. --- Cell biology. --- Biomedicine. --- Cancer Research. --- Cell Biology. --- Medical Microbiology. --- Biomedicine general. --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Cancer genes --- Cytology. --- Microbiology. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Microbial biology --- Biology --- Microorganisms --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Tumors --- Biomedicine, general. --- Health Workforce --- Cancer research