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2013 (3)

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Book
Understanding microbes : an introduction to a small world
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ISBN: 9781119978800 1119978807 9781119978794 1119978793 Year: 2013 Publisher: Chichester : Wiley-Blackwell,

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Abstract

"We can't see them, but microbes are the dominant form of life on Earth. They make up half of the world's biomass. They were here billions of years before we were, and they will be here after we are gone. Without their activity, life as we know it would be impossible. Even within our own bodies, there are ten times as many bacterial cells as human cells. Understanding Microbes provides a clear, accessible introduction to this world of microbes. As well as looking at a selection of infectious diseases, including how they are prevented and treated, the book explores the importance of microbes in the environment, in the production and preservation of food, and their applications in biotechnology.This lively and engaging book provides the basics of microbiology, in a contemporary context. It will be equally useful for students across the biological, environmental and health sciences, and for the curious reader wanting to learn more about this fascinating subject. A highly-readable, concise introduction to the basics of microbiology placed in the context of the very latest developments in molecular biology and their impact on the microbial world. Numerous real-world examples range from how cows digest grass to the role of microbes in cancer and the impact of climate change Well-illustrated in full colour throughout. Written by an Author with a proven track record in teaching, writing and research"--Provided by publisher.


Book
Between pathogenicity and commensalism
Authors: --- ---
ISBN: 3642432298 3642365590 3642365604 Year: 2013 Publisher: New York : Springer,

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Microbes colonize nearly every biotic and abiotic niche on our planet. This also includes our human body, which is densely populated with microbes, the majority of which interact with us in a commensal, sometimes even mutualistic, relationship. Only a minority of our microbiota are pathogenic organisms with the ability to cause infection. This book covers various aspects of the interplay between commensal and pathogenic bacteria with their hosts. The chapters summarize recent findings on the geno- and phenotypic traits of opportunistic bacterial pathogens, such as Escherichia coli, staphylococci or Pseudomonas aeruginosa, as well as the impact of commensal and probiotic bacteria on intestinal physiology and health. The differential interaction of pathogenic, commensal and probiotic bacteria with their host is reviewed from both the bacterial and the host’s perspective to round out this compilation of articles on the differences and similarities of pathogenic and commensal microorganisms.


Book
The Hologenome Concept: Human, Animal and Plant Microbiota
Authors: ---
ISBN: 3319042408 3319042416 Year: 2013 Publisher: Cham : Springer International Publishing : Imprint: Springer,

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Groundbreaking research over the last 10 years has given rise to the hologenome concept of evolution. This concept posits that the holobiont (host plus all of its associated microorganisms) and its hologenome (sum of the genetic information of the host and its symbiotic microorganisms), acting in concert, function as a unique biological entity and therefore as a level of selection in evolution. All animals and plants harbor abundant and diverse microbiota, including viruses. Often the amount of symbiotic microorganisms and their combined genetic information far exceed that of their host. The microbiota with its microbiome, together with the host genome, can be transmitted from one generation to the next and thus propagate the unique properties of the holobiont. The microbial symbionts and the host interact in a cooperative way that affects the health of the holobiont within its environment. Beneficial microbiota protects against pathogens, provides essential nutrients, catabolizes complex polysaccharides, renders harmful chemicals inert, and contributes to the performance of the immune system. In humans and animals, the microbiota also plays a role in behavior. The sum of these cooperative interactions characterizes the holobiont as a unique biological entity. Genetic variation in the hologenome can be brought about by changes in either the host genome or the microbial population genomes (microbiome). Evolution by cooperation can occur by amplifying existing microbes, gaining novel microbiota and by acquiring microbial and viral genes. Under environmental stress, the microbiome can change more rapidly and in response to more processes than the host organism alone and thus influences the evolution of the holobiont. Prebiotics, probiotics, synbiotics and phage therapy are discussed as applied aspects of the hologenome concept.

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