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The beginning of interphase cytogenetics can be attributed to significant advances in human molecular genetics and cytogenetics. Owing to experimental and theoretical research at the interface between cellular and molecular levels of chromosomal organization and function, high-resolution techniques for chromosomal analysis (molecular cytogenetic techniques) have become available. Molecular cytogenetics is a branch of biomedical sciences that explores chromosomes at molecular and single-cell resolutions at all stages of the cell cycle. It also comprises the techniques that operate with either the entire genome or specific DNA sequences to analyze genomic structural and functional variations at chromosomal level. In postgenomic era, molecular cytogenetics has appreciably transformed and has given rise to a new field of genomics, called cytogenomics. As a result, new opportunities have emerged for analysis of human interphase chromosomes in almost all cell types and states at unprecedented resolution. In Human Interphase Chromosomes, the editors have provided an overview of current developments in the study of human interphase chromosomes with a special attention to available molecular cytogenetictechnologies for basic and clinical chromosome research.
Human cytogenetics --- Human chromosomes --- Chromosomes, Mammalian --- Biology --- Cell Cycle --- Cytological Techniques --- Cell Physiological Processes --- Chromosomes --- Biological Science Disciplines --- Clinical Laboratory Techniques --- Natural Science Disciplines --- Investigative Techniques --- Cell Physiological Phenomena --- Cellular Structures --- Cells --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Phenomena and Processes --- Disciplines and Occupations --- Anatomy --- Cytogenetic Analysis --- Interphase --- Chromosomes, Human --- Genetics --- Medicine --- Health & Biological Sciences --- Pathology --- Cytogenetics. --- Chromosomes. --- Chromosome theory --- Medicine. --- Human genetics. --- Cell biology. --- Biomedicine. --- Human Genetics. --- Cell Biology. --- Cytology --- Cell nuclei --- Crossing over (Genetics) --- Cytotaxonomy --- Karyokinesis --- Linkage (Genetics) --- Cytology. --- Cell biology --- Cellular biology --- Cytologists --- Heredity, Human --- Human biology --- Physical anthropology
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Principles of Molecular Diagnostics and Personalized Cancer Medicine The role of molecular genetics in the treatment of malignancy continues to grow at an astonishing rate. Today's subspecialized multidisciplinary approach to oncology has incorporated advances in targeted molecular therapy, prognosis, risk assessment, and prevention-all based at least in part on molecular diagnostics and imaging. Inside this cutting-edge resource, readers will explore broad, comprehensive perspectives on the current trends in molecular diagnosis of cancer and personalized cancer medicine. Authoritative discuss
Tumors --- Oncology --- Molecular diagnosis. --- Diagnosis --- Molecular diagnostics --- Molecular biology --- Neoplasms --- Tumours --- Pathology --- Cysts (Pathology) --- Diagnosis. --- Treatment. --- Methodology. --- Molecular aspects --- Individualized Medicine --- Medical Oncology --- Molecular Diagnostic Techniques --- Molecular Targeted Therapy --- Cancer --- Personalized medicine. --- diagnosis --- therapy --- methods --- Individualized medicine --- Personalized medicine --- Medical care --- Pharmacogenetics --- Cancer therapy --- Cancer treatment --- Targeted Molecular Therapy --- Molecular Targeted Therapies --- Molecular Therapy, Targeted --- Targeted Molecular Therapies --- Targeted Therapy, Molecular --- Therapy, Molecular Targeted --- Therapy, Targeted Molecular --- Molecular Diagnostic Technics --- Molecular Diagnostic Testing --- Molecular Testing --- Diagnostic Technic, Molecular --- Diagnostic Technics, Molecular --- Diagnostic Technique, Molecular --- Diagnostic Techniques, Molecular --- Diagnostic Testing, Molecular --- Molecular Diagnostic Technic --- Molecular Diagnostic Technique --- Technic, Molecular Diagnostic --- Technics, Molecular Diagnostic --- Technique, Molecular Diagnostic --- Techniques, Molecular Diagnostic --- Testing, Molecular --- Testing, Molecular Diagnostic --- Genetic Testing --- Cytogenetic Analysis --- P Health --- P-Health --- Personalized Medicine --- Theranostics --- Predictive Medicine --- Medicine, Individualized --- Medicine, Personalized --- Medicine, Precision --- Medicine, Predictive --- Theranostic --- Pharmacogenomic Variants --- Patient-Specific Modeling --- Therapy
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"This book covers the core scientific principles necessary for an understanding of medical genetics and its clinical applications, while also considering the social implications of genetic disorders. This third edition has been fully updated to include the latest developments in the field, covering the most common genetic anomalies, their diagnosis and management, in clear, concise and revision-friendly sections to complement any health science course."--Publisher.
Genetic Diseases, Inborn. --- Chromosome Aberrations. --- Genetics, Medical. --- Medical genetics. --- Developmental biology. --- Génétique médicale --- Biologie du développement --- Medical genetics --- Developmental biology --- Genetic Diseases, Inborn --- Chromosome Aberrations --- Genetics, Medical --- Genetic Testing --- Genetic Screening --- Predictive Genetic Testing --- Predictive Testing, Genetic --- Testing, Genetic Predisposition --- Genetic Predisposition Testing --- Genetic Predictive Testing --- Genetic Screenings --- Genetic Testing, Predictive --- Predisposition Testing, Genetic --- Screening, Genetic --- Screenings, Genetic --- Testing, Genetic --- Testing, Genetic Predictive --- Testing, Predictive Genetic --- Genetic Predisposition to Disease --- Prenatal Diagnosis --- Preimplantation Diagnosis --- Cytogenetic Analysis --- Molecular Diagnostic Techniques --- Databases, Genetic --- Databases, Nucleic Acid --- Genetic Privacy --- Medical Genetics --- Anthropology, Physical --- Chromosome Disorders --- Sex Chromosome Disorders --- Molecular Medicine --- Abnormalities, Autosome --- Abnormalities, Chromosomal --- Abnormalities, Chromosome --- Chromosomal Aberrations --- Chromosome Abnormalities --- Cytogenetic Abnormalities --- Autosome Abnormalities --- Cytogenetic Aberrations --- Aberration, Chromosomal --- Aberration, Chromosome --- Aberration, Cytogenetic --- Aberrations, Chromosomal --- Aberrations, Chromosome --- Aberrations, Cytogenetic --- Abnormalities, Cytogenetic --- Abnormality, Autosome --- Abnormality, Chromosomal --- Abnormality, Chromosome --- Abnormality, Cytogenetic --- Autosome Abnormality --- Chromosomal Aberration --- Chromosomal Abnormalities --- Chromosomal Abnormality --- Chromosome Aberration --- Chromosome Abnormality --- Cytogenetic Aberration --- Cytogenetic Abnormality --- Chromosomes --- Cytogenetics --- Genetic Diseases --- Genetic Disorders --- Hereditary Disease --- Inborn Genetic Diseases --- Single-Gene Defects --- Hereditary Diseases --- Defect, Single-Gene --- Defects, Single-Gene --- Disease, Genetic --- Disease, Hereditary --- Disease, Inborn Genetic --- Diseases, Genetic --- Diseases, Hereditary --- Diseases, Inborn Genetic --- Disorder, Genetic --- Disorders, Genetic --- Genetic Disease --- Genetic Disease, Inborn --- Genetic Disorder --- Inborn Genetic Disease --- Single Gene Defects --- Single-Gene Defect --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Clinical genetics --- Diseases --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- diagnosis --- abnormalities --- Genetic aspects --- medische genetica --- aangeboren afwijkingen --- Genetic disorders. --- Chromosome abnormalities. --- Genetic screening.
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Molecular Genetic Pathology, Second Edition presents up-to-date material containing fundamental information relevant to the clinical practice of molecular genetic pathology. Fully updated in each area and expanded to include identification of new infectious agents (H1N1), new diagnostic biomarkers and biomarkers for targeted cancer therapy. This edition is also expanded to include the many new technologies that have become available in the past few years such as microarray (AmpliChip) and high throughput deep sequencing, which will certainly change the clinical practice of molecular genetic pathology. Part I examines the clinical aspects of molecular biology and technology, genomics. Poharmacogenomics and proteomics, while Part II covers the clinically relevant information of medical genetics, hematology, transfusion medicine, oncology, and forensic pathology. Supplemented with many useful figures and presented in a helpful bullet-point format, Molecular Genetic Pathology, Second Edition provides a unique reference for practicing pathologists, oncologists, internists, and medical genetisists. Furthermore, a book with concise overview of the field and highlights of clinical applications will certainly help those trainees, including pathology residents, genetics residents, molecular pathology fellows, internists, hematology/oncology fellows, and medical technologists in preparing for their board examination/certification.
Medicine. --- Medical laboratories. --- Hematology. --- Oncology. --- Pathology. --- Medicine & Public Health. --- Laboratory Medicine. --- Pathology --- Investigative Techniques --- Clinical Laboratory Techniques --- Molecular Biology --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biochemistry --- Medicine --- Biological Science Disciplines --- Health Occupations --- Natural Science Disciplines --- Disciplines and Occupations --- Pathology, Molecular --- Pathology, Clinical --- Methods --- Molecular Diagnostic Techniques --- Health & Biological Sciences --- Molecular Diagnostic Technics --- Molecular Diagnostic Testing --- Diagnostic Technic, Molecular --- Diagnostic Technics, Molecular --- Diagnostic Technique, Molecular --- Diagnostic Techniques, Molecular --- Diagnostic Testing, Molecular --- Molecular Diagnostic Technic --- Molecular Diagnostic Technique --- Technic, Molecular Diagnostic --- Technics, Molecular Diagnostic --- Technique, Molecular Diagnostic --- Techniques, Molecular Diagnostic --- Testing, Molecular Diagnostic --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Clinical Pathology --- Diagnostic Molecular Pathology --- Molecular Diagnostics --- Diagnostic Molecular Pathologies --- Diagnostic, Molecular --- Diagnostics, Molecular --- Molecular Diagnostic --- Molecular Pathologies --- Molecular Pathologies, Diagnostic --- Molecular Pathology --- Molecular Pathology, Diagnostic --- Pathologies, Diagnostic Molecular --- Pathologies, Molecular --- Pathology, Diagnostic Molecular --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Health Professions --- Health Occupation --- Health Profession --- Occupation, Health --- Occupations, Health --- Profession, Health --- Professions, Health --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Medical Specialities --- Medical Specialties --- Medical Specialty --- Specialities, Medical --- Specialties, Medical --- Specialty, Medical --- Medical Speciality --- Speciality, Medical --- Biochemical Genetics --- Biology, Molecular --- Genetics, Biochemical --- Genetics, Molecular --- Molecular Genetics --- Biochemical Genetic --- Genetic, Biochemical --- Genetic, Molecular --- Molecular Genetic --- Diagnoses and Laboratory Examinations --- Diagnosis, Laboratory --- Laboratory Diagnosis --- Laboratory Examinations and Diagnoses --- Laboratory Techniques, Clinical --- Clinical Laboratory Technique --- Diagnoses, Laboratory --- Laboratory Diagnoses --- Laboratory Technique, Clinical --- Technique, Clinical Laboratory --- Techniques, Clinical Laboratory --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Pathologies --- Disease --- Disease (Pathology) --- Haematology --- Clinical sciences --- Medical profession --- pathology --- Laboratory medicine. --- Oncology . --- Medical sciences --- Diseases --- Medicine, Preventive --- Internal medicine --- Blood --- Health facilities --- Laboratories --- Tumors --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Diagnosis --- Pathology Clinical --- Molecular Diagnostic Techniques. --- methods. --- Molecular Testing --- Testing, Molecular --- Genetic Testing --- Cytogenetic Analysis --- Biology --- Biomedical Research. --- Research. --- Biological research --- Biomedical research --- Health Workforce
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