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Serotonin --- Neural transmission. --- Neurochemistry. --- Biochemistry --- Neurosciences --- Nerve transmission --- Nervous transmission --- Neurotransmission --- Synaptic transmission --- Transmission of nerve impulses --- Neural circuitry --- Neurophysiology --- Neurotransmitters --- Physiological effect.

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In 1961, neurobiologists found that the conduction velocity of the nerve impulse in the giant nerve fiber of the Penaeus shrimp abdominal nerve cord was over 200 m/s, the highest speed of information transmission ever observed in the animal kingdom. The peculiar myelin sheath with its unique nodal structure and the electrical properties of the nerve fibers of the shrimp have continued to be investigated for a quarter of century and are now fully described in this book. The investigation dispels the commonly held belief that the fastest recorded impulse conduction is about 120 m/s in the thickest vertebrate myelinated nerve fibers. In the shrimp, researchers found a completely novel type of functional node in the giant fiber which they designated as the fenestration node. In portions of the myelinated fiber, the fenestration node furnished the sites of excitation. Also discovered was a new strategy for increasing impulse conduction in the shrimp. The book includes a section on the formation of the fenestration node and the discovery of a strategy that allows the shrimp to escape its predators by an action of the fastest velocity. The data presented in this volume on the myelin sheath of invertebrates present a new direction for this field and a rich source of information for neurobiologists worldwide.

Marine anatomy. --- Myelinated neurofibrils. --- Nerve tissue. --- Myelinated neurofibrils --- Neural conduction --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- Neural transmission. --- Shrimps --- Physiology. --- Macroura --- Macrura --- Natantia (Decapoda) --- Prawns --- Shrimp --- Nerve transmission --- Nervous transmission --- Neurotransmission --- Synaptic transmission --- Transmission of nerve impulses --- Life sciences. --- Neurosciences. --- Biochemistry. --- Cell physiology. --- Cell membranes. --- Neurobiology. --- Life Sciences. --- Animal Biochemistry. --- Cell Physiology. --- Membrane Biology. --- Neural circuitry --- Neurophysiology --- Neurotransmitters --- Decapoda (Crustacea) --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes (Biology) --- Glycocalyces --- Cell function --- Cytology --- Physiology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Neural sciences --- Neurological sciences --- Nervous system --- Neurosciences --- Composition --- Cell membranes .

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Glutamate is the primary excitatory neurotransmitter in the CNS and disturbances in glutamate transport contribute to a number of neurological and neurodegenerative disorders.  Appropriate levels of cholesterol are very important for the proper functioning of glutamate transport while unbalanced levels of cholesterol have been implicated in the pathogenesis of disorders such as stroke, ischemia, traumatic brain injury, and neurotoxicity.   In the proposed book, the author presents data from the literature and from her own lab to address the extent to and way in which membrane cholesterol modulates presynaptic glutamate transport and whether lowering the level of cholesterol available can offer some neuroprotective benefits.

Cholesterol -- Physiological effect. --- Neurobiology. --- Neurotransmitters. --- Neurobiology --- Neurotransmitters --- Cholesterol --- Glutamic Acid --- Axons --- Signal Transduction --- Electrophysiological Processes --- Sterols --- Synapses --- Physiological Effects of Drugs --- Cholestenes --- Molecular Mechanisms of Pharmacological Action --- Nervous System Physiological Processes --- Biochemical Processes --- Cholestanes --- Pharmacologic Actions --- Physiological Processes --- Cell Physiological Processes --- Amino Acids, Dicarboxylic --- Intercellular Junctions --- Nervous System --- Nerve Fibers --- Electrophysiological Phenomena --- Amino Acids, Acidic --- Neurons --- Lipids --- Nervous System Physiological Phenomena --- Membrane Lipids --- Steroids --- Chemical Actions and Uses --- Amino Acids --- Biochemical Phenomena --- Chemicals and Drugs --- Cells --- Cell Physiological Phenomena --- Cell Membrane Structures --- Anatomy --- Physiological Phenomena --- Chemical Processes --- Musculoskeletal and Neural Physiological Phenomena --- Cell Membrane --- Phenomena and Processes --- Polycyclic Compounds --- Chemical Phenomena --- Amino Acids, Peptides, and Proteins --- Cellular Structures --- Synaptic Transmission --- Presynaptic Terminals --- Neurotransmitter Agents --- Glutamates --- Human Anatomy & Physiology --- Medicine --- Health & Biological Sciences --- Neuroscience --- Neurology --- Physiological effect --- Physiological effect. --- Cholesterin --- Chemical nerve transmitters --- Nerve transmitter substances --- Neural transmitters --- Neurohumors --- Neuroregulators --- Synaptic transmitters --- Transmitters, Chemical nerve --- Transmitters, Synaptic --- Medicine. --- Neurosciences. --- Neurochemistry. --- Biomedicine. --- Isopentenoids --- Low-cholesterol diet --- Neurochemistry --- Neural transmission --- Neurosciences --- Neural sciences --- Neurological sciences --- Medical sciences --- Nervous system --- Biochemistry