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In this book we have taken a comprehensive look at the subject of familial and hereditary gastric tumors. In particular, the aim of this novel editorial work is to propose the correct management of hereditary diffuse gastric cancer patients, focusing in particular on E-cadherin germline mutations, clinical criteria definition, genetic screening and molecular mechanisms, pathology and microscopic features, surgical treatment and clinical approach for asymptomatic mutation carriers. We also describe other inherited predispositions involving gastric carcinoma.

Cancer -- Genetic aspects. --- Neoplasms -- genetics. --- Stomach --- Disease Susceptibility --- Gastrointestinal Neoplasms --- Neoplasms --- Biology --- Digestive System Neoplasms --- Biological Science Disciplines --- Diseases --- Disease Attributes --- Neoplasms by Site --- Pathologic Processes --- Natural Science Disciplines --- Pathological Conditions, Signs and Symptoms --- Disciplines and Occupations --- Genetic Predisposition to Disease --- Neoplastic Syndromes, Hereditary --- Stomach Neoplasms --- Genetics --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Genetic aspects --- Cancer. --- Diseases. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Gastric diseases --- Medicine. --- Cancer research. --- Human genetics. --- Gastroenterology. --- Biomedicine. --- Cancer Research. --- Biomedicine general. --- Human Genetics. --- Tumors --- Oncology. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Heredity, Human --- Physical anthropology --- Internal medicine --- Digestive organs --- Gastroenterology . --- Biomedicine, general. --- Health Workforce --- Cancer research