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Book
Morphine and metastasis
Author:
ISBN: 9400792964 9400756771 940075678X 128391087X Year: 2013 Publisher: New York : Springer,

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Abstract

The possibility that morphine and other opioids may modulate tumour growth and metastasis has been researched for many years. The recent past has seen multiple clinical studies attempting to document whether limiting the perioperative use of morphine is beneficial for cancer surgery patients. Furthermore, a lot of exciting new data has been generated in vitro, but also in preclinical and clinical studies, that indirectly shed light on the effect of opioids on cancer. This book combines chapters written by qualified experts around the world whose research encompasses the effect of morphine or other opioids on tumour growth and metastasis. This includes clinicians, researchers working on animal models and studying the effect of morphine on tumours, and most importantly the mechanism for this effect, and lastly cell biologists. Current investigations and cross talk between basic science and clinical trials will refine our understanding of the multiple levels of actions of morphine and other opioids on tumour growth and metastasis, and result in improved guidelines for patient care. This book will be of interest to clinicians, especially those dealing with cancer patients and their pain management, as well as students, teachers and scientists in the fields of anaesthesiology, oncology, tumour biology, immunology, opioid pharmacology.

Keywords

Morphine -- Therapeutic use. --- Morphine. --- Opioids. --- Metastasis --- Growth Substances --- Therapeutics --- Morphinans --- Biological Science Disciplines --- Neoplastic Processes --- Neoplasms --- Phenanthrenes --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pathologic Processes --- Opiate Alkaloids --- Natural Science Disciplines --- Heterocyclic Compounds with 4 or More Rings --- Heterocyclic Compounds, Bridged-Ring --- Physiological Effects of Drugs --- Heterocyclic Compounds --- Pathological Conditions, Signs and Symptoms --- Disciplines and Occupations --- Diseases --- Pharmacologic Actions --- Polycyclic Hydrocarbons, Aromatic --- Alkaloids --- Chemicals and Drugs --- Chemical Actions and Uses --- Polycyclic Compounds --- Morphine --- Growth Inhibitors --- Pharmacology --- Neoplasm Metastasis --- Drug Therapy --- Medicine --- Health & Biological Sciences --- Oncology --- Metastasis. --- Cancer --- Chemotherapy. --- Cancer metastasis --- Dissemination of cancer --- Metastases --- Metastatic cancer --- Neoplasm metastasis --- Spread of cancer --- Tumor dissemination --- Tumor metastasis --- Tumor spread --- Morphia --- Dissemination --- Medicine. --- Pharmacy. --- Cancer research. --- Pharmacology. --- Oncology. --- Pain medicine. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Pain Medicine. --- Antineoplastic agents --- Pathology --- Cancer invasiveness --- Cancer of unknown primary origin --- Narcotics --- Opium --- Treatment --- Toxicology. --- Oncology  . --- Tumors --- Chemicals --- Poisoning --- Poisons --- Chemistry --- Drugs --- Materia medica --- Toxicology --- Algiatry --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Pharmacy --- Cancer research --- Physiological effect


Book
Handbook of methadone prescribing and buprenorphine therapy
Authors: ---
ISBN: 1493901818 1461469732 1461469740 Year: 2013 Publisher: New York : Springer,

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Abstract

Methadone and buprenorphine are the only two opioids that are indicated for the management of both pain and opioid-related drug addiction.  Both present unique challenges to the general practitioner and pain specialist, requiring a separate analysis from the rest of the drugs in the same family.  Handbook of Methadone Prescribing and Buprenorphine Therapy is an invaluable guide to the safe use of these opioids.  Authored by clinical and academic leaders from a variety of settings and backgrounds, this book includes chapters on pharmacology, adverse effects, safe rotation from other opioids, cardiac toxicity, prescribing, pharmacokinetics, equianalgesic dose, and replacement therapy. This comprehensive text provides clinicians, researchers, policy-makers and academicians a resource for all the relevant points in methadone prescribing and buprenorphine therapy.

Keywords

Buprenorphine -- Handbooks, manuals, etc. --- Drugs -- Prescribing -- Handbooks, manuals, etc. --- Methadone maintenance -- Handbooks, manuals, etc. --- Methadone maintenance --- Ketones --- Substance-Related Disorders --- Therapeutics --- Morphinans --- Neurologic Manifestations --- Analgesics --- Diseases --- Nervous System Diseases --- Opiate Alkaloids --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Sensory System Agents --- Organic Chemicals --- Alkaloids --- Chemicals and Drugs --- Peripheral Nervous System Agents --- Heterocyclic Compounds --- Physiological Effects of Drugs --- Pharmacologic Actions --- Chemical Actions and Uses --- Buprenorphine --- Pain --- Drug Therapy --- Analgesics, Opioid --- Opiate Substitution Treatment --- Methadone --- Opioid-Related Disorders --- Medicine --- Surgery & Anesthesiology --- Health & Biological Sciences --- Pathology --- Anesthesiology --- Methadone maintenance. --- Buprenorphine. --- Methadone hydrochloride --- Methadone treatment programs --- Therapeutic use --- Medicine. --- Anesthesiology. --- Internal medicine. --- Oncology. --- Neurology. --- Pain medicine. --- Rehabilitation medicine. --- Medicine & Public Health. --- Pain Medicine. --- Rehabilitation Medicine. --- Internal Medicine. --- Morphine --- Narcotic antagonists --- Drug abuse --- Derivatives --- Treatment --- Rehabilitation. --- Oncology  . --- Tumors --- Medicine, Internal --- Anaesthesiology --- Surgery --- Nervous system --- Neuropsychiatry --- Algiatry --- Neurology . --- Medicine, Rehabilitation --- Rehabilitation medicine --- Rehabilitation --- Medicine, Physical

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