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Electrochemistry --- Electrochemistry. --- Chemical Phenomena. --- Chemistry, Physical and theoretical --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Chemical Processes --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Electrochemistries --- Chemistry
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The series Topics in Current Chemistry presents critical reviews of the present and future trends in modern chemical research. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science.The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience.Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field.
Chemistry. --- Medicine. --- Analytical biochemistry. --- Chemistry, Organic. --- Organic Chemistry. --- Analytical Chemistry. --- Biomedicine general. --- Chromatographic analysis --- Enantiomers --- Isomerism --- Organic Chemistry Phenomena --- Chemical Phenomena --- Phenomena and Processes --- Stereoisomerism --- Chemistry --- Physical Sciences & Mathematics --- Biochemistry --- Analysis --- Differentiation --- Stereochemistry, Molecular --- Molecular Stereochemistry --- Stereoisomers --- Stereoisomer --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Chemical Processes --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Organic Chemistry Phenomenon --- Organic Chemistry Process --- Organic Chemistry Concepts --- Organic Chemistry Processes --- Chemistry Process, Organic --- Chemistry Processes, Organic --- Concept, Organic Chemistry --- Concepts, Organic Chemistry --- Organic Chemistry Concept --- Phenomena, Organic Chemistry --- Phenomenon, Organic Chemistry --- Process, Organic Chemistry --- Processes, Organic Chemistry --- Isomerisms --- Antipodes, Optical --- Enantiomorphs --- Isomers, Mirror-image --- Mirror-image isomers --- Optical antipodes --- Analysis, Chromatographic --- Chromatography --- Organic chemistry --- Analytic biochemistry --- Clinical sciences --- Medical profession --- Analytical chemistry. --- Organic chemistry. --- Chromatographic analysis. --- Analysis. --- Differentiation. --- Optical isomers --- Chirality --- Chemistry, Analytic --- Phase partition --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Biomedicine, general. --- Health Workforce --- Analytical chemistry --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Medicine --- Analytical biochemistry --- Chemistry, Organic
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Glyco-engineering is being developed as a method to control the composition of carbohydrates and to enhance the pharmacological properties of monoclonal antibodies (mAbs) and other proteins. In Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols, experts in the field provide readers with production and characterization protocols of glycoproteins and glyco-engineered biopharmaceuticals with a focus on mAbs. The volume is divided in four complementary parts dealing with glyco-engineering of therapeutic proteins, glycoanalytics, glycoprotein complexes characterization, and PK/PD assays for therapeutic antibodies. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Glycosylation Engineering of Biopharmaceuticals: Methods and Protocols serves as an ideal guide for scientists striving to push forward the exciting field of engineered biopharmaceuticals.
Pharmaceutical biotechnology --- Glycosylation --- Biopharmaceutics --- Glycoconjugates --- Investigative Techniques --- Pharmacology --- Carbohydrate Metabolism --- Antibodies --- Biological Science Disciplines --- Carbohydrates --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Biochemical Processes --- Immunoglobulins --- Natural Science Disciplines --- Biochemical Phenomena --- Chemicals and Drugs --- Immunoproteins --- Blood Proteins --- Chemical Phenomena --- Disciplines and Occupations --- Proteins --- Phenomena and Processes --- Amino Acids, Peptides, and Proteins --- Methods --- Glycoproteins --- Antibodies, Monoclonal --- Health & Biological Sciences --- Pharmacy, Therapeutics, & Pharmacology --- Glycosylation. --- Pharmaceutical biotechnology. --- Biopharmaceutics. --- Biotechnologie pharmaceutique --- Biopharmacie --- therapeutic use. --- methods. --- Monoclonal Antibodies --- Protein Glycosylation --- Glycosylation, Protein --- Glycosylations --- Glycosylations, Protein --- Protein Glycosylations --- Glycoprotein --- Neoglycoproteins --- Methodological Studies --- Methodological Study --- Procedures --- Studies, Methodological --- Study, Methodological --- Method --- Procedure --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Chemical Processes --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Plasma Proteins --- Serum Proteins --- Proteins, Blood --- Proteins, Plasma --- Proteins, Serum --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Immunoglobulin --- Globulins, Immune --- Immune Globulins --- Carbohydrate --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Metabolism, Carbohydrate --- Pharmacologies --- Pharmaceutical Preparations --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Glycation --- Biopharmaceutical technology --- Drugs --- blood --- metabolism --- pharmacology --- Biotechnology --- Medicine. --- Pharmacology. --- Biochemical engineering. --- Biomedicine. --- Pharmacology/Toxicology. --- Biochemical Engineering. --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Chemical engineering --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Pharmacy --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Physiological effect --- Toxicology. --- Medicine --- Poisoning --- Poisons --- Toxicology
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Dennis R. Salahub et al. Recent Progress in Density Functional Methodology for Biomolecular Modeling Eugene Serge Kryachko Density Functional Theory and Molecular Interactions: Dispersion Interactions Radu Silaghi-Dumitrescu Redox Activation of Small Molecules at Biological Metal Centers Mauro Causà et al. The Bond Analysis Techniques (ELF and Maximum Probability Domains) to a Family of Models Relevant to Bio-Inorganic Chemistry Arindam Chakraborty et al. Biological Activity and Toxicity: A Conceptual DFT Approach Mihai V. Putz and Ana-Maria Putz DFT Chemical Reactivity Driven by Biological Activity: Applications for the Toxicological Fate of Chlorinated PAHs.
Density functionals --- Chemistry, Inorganic --- Biochemistry --- Chemical Phenomena --- Models, Theoretical --- Biochemical Phenomena --- Chemistry --- Phenomena and Processes --- Biological Science Disciplines --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Natural Science Disciplines --- Disciplines and Occupations --- Molecular Structure --- Models, Chemical --- Chemistry, Bioinorganic --- Physicochemical Phenomena --- Physical Sciences & Mathematics --- Inorganic Chemistry --- Physical & Theoretical Chemistry --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Chemical Processes --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Biological Inorganic Chemistry --- Biochemistry, Inorganic --- Bioinorganic Chemistry --- Biochemistries, Inorganic --- Bioinorganic Chemistries --- Biological Inorganic Chemistries --- Chemistries, Bioinorganic --- Chemistries, Biological Inorganic --- Chemistry, Biological Inorganic --- Inorganic Biochemistries --- Inorganic Biochemistry --- Inorganic Chemistries, Biological --- Inorganic Chemistry, Biological --- Chemical Models --- Chemical Model --- Model, Chemical --- Structure, Molecular --- Molecular Structures --- Structures, Molecular --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Processes --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Experimental Model --- Experimental Models --- Mathematical Model --- Model, Experimental --- Models (Theoretical) --- Models, Experimental --- Models, Theoretic --- Theoretical Study --- Mathematical Models --- Model (Theoretical) --- Model, Mathematical --- Model, Theoretical --- Models, Mathematical --- Studies, Theoretical --- Study, Theoretical --- Theoretical Model --- Theoretical Models --- Theoretical Studies --- Chemistries, Inorganic --- Inorganic Chemistries --- Inorganic chemistry --- Density functional methods --- Density functional theory --- Functional methods, Density --- Functionals, Density --- Chemistry. --- Inorganic chemistry. --- Inorganic Chemistry. --- Density functionals. --- Chemistry, Inorganic. --- Inorganic compounds --- Functional analysis --- Chemistry, inorganic.
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Peter P. Borbat, Jack H. Freed Pulse Dipolar Electron Spin Resonance: Distance Measurements Gunnar Jeschke Interpretation of Dipolar EPR Data in Terms of Protein Structure Sandip A. Shelke and Snorri Th. Sigurdsson Site-Directed Nitroxide Spin Labeling of Biopolymers Daniella Goldfarb Metal-Based Spin Labeling for Distance Determination Johann P. Klare, Heinz-Jürgen Steinhoff Structural Information from Spin-Labelled Membrane-Bound Proteins Richard Ward and Olav Schiemann Structural Information from Oligonucleotides Claudia E. Tait, Alice M. Bowen, Christiane R. Timmel, Jeffrey Harmer rientation selective DEER using rigid spin labels, cofactors, metals, and clusters.
Chemistry. --- Chemistry, inorganic. --- Chemistry, Physical organic. --- Biochemistry. --- Inorganic Chemistry. --- Protein Structure. --- Physical Chemistry. --- Ultrastructure (Biology) --- Spin labels --- Paramagnetism --- Biochemical Phenomena --- Free Radicals --- Magnetic Resonance Spectroscopy --- Organic Chemicals --- Spectrum Analysis --- Chemical Phenomena --- Phenomena and Processes --- Chemicals and Drugs --- Chemistry Techniques, Analytical --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Molecular Structure --- Electron Spin Resonance Spectroscopy --- Spin Labels --- Chemistry --- Physical Sciences & Mathematics --- Inorganic Chemistry --- Labels, Spin --- Electron Spin Resonance --- ENDOR --- Electron Nuclear Double Resonance --- Electron Paramagnetic Resonance --- Paramagnetic Resonance --- Paramagnetic Resonance, Electron --- Resonance, Electron Paramagnetic --- Resonance, Electron Spin --- Resonance, Paramagnetic --- Structure, Molecular --- Molecular Structures --- Structures, Molecular --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Analytical Chemistry Methods --- Analytical Chemistry Techniques --- Analytical Chemistry Method --- Analytical Chemistry Technique --- Chemistry Method, Analytical --- Chemistry Methods, Analytical --- Chemistry Technique, Analytical --- Method, Analytical Chemistry --- Methods, Analytical Chemistry --- Technique, Analytical Chemistry --- Techniques, Analytical Chemistry --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Chemical Processes --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Analysis, Spectrum --- Spectrometry --- Spectroscopy --- Chemicals, Organic --- In Vivo NMR Spectroscopy --- MR Spectroscopy --- Magnetic Resonance --- NMR Spectroscopy --- NMR Spectroscopy, In Vivo --- Nuclear Magnetic Resonance --- Spectroscopy, Magnetic Resonance --- Spectroscopy, NMR --- Spectroscopy, Nuclear Magnetic Resonance --- Magnetic Resonance Spectroscopies --- Magnetic Resonance, Nuclear --- NMR Spectroscopies --- Resonance Spectroscopy, Magnetic --- Resonance, Magnetic --- Resonance, Nuclear Magnetic --- Spectroscopies, NMR --- Spectroscopy, MR --- Radicals, Free --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Processes --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Spin labeling --- Fine structure (Biology) --- Nanobiology --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry, Physical organic --- Inorganic chemistry --- Composition --- Inorganic chemistry. --- Physical chemistry. --- Proteins. --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Biology --- Medical sciences --- Inorganic compounds --- Spin labels. --- Cells --- Microstructure --- Nanoscience --- Biophysical labeling --- Electron paramagnetic resonance --- Molecular rotation --- Proteins . --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Proteids --- Biomolecules --- Polypeptides --- Proteomics
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