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Cilia are tiny microtubule-based organelles projecting from the plasma membrane of practically all cells in the body. In the past 10 years a flurry of research has indicated a crucial role of this long-neglected organelle in the development and function of the central nervous system. A common theme of these studies is the critical dependency of signal transduction of the Sonic hedgehog, and more recently, Wnt signaling pathways upon cilia to regulate fate decisions and morphogenesis. Both primary and motile cilia also play crucial roles in the function of the nervous system, including the primary processing of sensory information, the control of body mass, and higher functions such as behavior and cognition, serving as "antennae" for neurons to sense and  process their environment. In this book we describe the structure and function of cilia and the various tissues throughout the brain and spinal cord that are dependent upon cilia for their proper development and function.

Cilia -- Physiology. --- Cilia and ciliary motion. --- Epithelium. --- Nervous system -- Growth. --- Nervous system --- Growth. --- Medicine. --- Cancer research. --- Human physiology. --- Neurosciences. --- Developmental biology. --- Neurobiology. --- Biomedicine. --- Biomedicine general. --- Human Physiology. --- Cancer Research. --- Developmental Biology. --- Tissues --- Cilia and ciliary motion --- Developmental neurobiology --- Cells --- Microorganisms --- Epithelium --- Motility --- Oncology. --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Tumors --- Human biology --- Medical sciences --- Physiology --- Human body --- Neural sciences --- Neurological sciences --- Neuroscience --- Neurosciences --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Biomedicine, general. --- Health Workforce --- Cancer research --- Cancer --- Research.

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This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers cilia and includes chapters on such topics as electron microscopy of IFT in cilia and flagella, radial spoke isolation and assays, and biomechanical measurements of kinocilium. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers ciliaContains chapters on such topics as electron microscopy of IFT in cilia and flagella, radial

Cell movement. --- Cells -- History. --- Cells -- Motility. --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Proteindesign. --- Zilie. --- Cilia and ciliary motion. --- Cells --- Microorganisms --- Epithelium --- Motility --- Flagella (Microbiology) --- Enzymology. --- Motility.

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Sebastian Hensel (1830-98), nephew of the composer, virtuoso pianist and conductor Felix Mendelssohn (1809-47), originally intended this work to be 'not only of the family but for the family', drawing on their letters and diaries. Persuaded by friends to publish his narrative in 1879, Hensel in particular provides a first-hand insight into the lives of his uncle, lionized by the music-loving public of his day, and Felix's beloved sister Fanny (1805-47), herself a talented composer and pianist. Translated from the German revised second edition by Felix's close friend, diplomat Carl Klingemann (1798-1862), this 1881 two-volume collection made available for the first time in English a great deal of valuable source material. Covering the period 1729-1835, Volume 1 charts the family's history from the birth of philosopher Moses Mendelssohn to the death of his son, banker Abraham Mendelssohn Bartholdy, who was the father of Felix.

Mendelssohn family. --- Hensel, Fanny Mendelssohn, --- Mendelssohn-Bartholdy, Felix, --- Mendelʹson-Bartolʹdi, Feliks, --- Mendelʹson, Feliks, --- Men-te-erh-sung, F., --- Mendelssohn-Bartholdy, Jakob Ludwig Felix, --- Bartholdy, Felix Mendelssohn-, --- Mendelssohn, Felix, --- Mendelssohn, F. --- Mendelssohn-Bartholdy, F. --- Mendelson-Bartoldi, F. --- Bartolʹdi, Feliks Mendelʹson-, --- Mendelson-Bertoldi, Feliḳs, --- Bertoldi, Feliḳs Mendelson-, --- Mendelssohn-Bartholdy, Jacob Ludwig Felix, --- מנדלסון־ברתולדי, פליקס --- מענדעלסאהן, פעליקס, --- Mendelsohn-Bartholdy, Felix, --- Hensel, Fanny Cäcilia Mendelssohn-Bartholdy, --- Mendelssohn-Bartholdy, Fanny, --- Mendelssohn, Fanny, --- Mendelssohn-Hensel, Fanny, --- Hensel-Mendelssohn, Fanny, --- Bartholdy, Fanny Mendelssohn-, --- Mendelssohn-Bartholdy, Felix --- Mendelssohn, Felix --- Mendelssohn-Bartholdy, Jakob Ludwig Felix