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The new 4th edition of Histopathology of Preclinical Toxicity Studies is now completely in full color and continues to describe the pathology found in drug safety studies in laboratory animals with an evidence-based discussion of the relevance of these findings to the clinical investigation of new drugs for humans. Organized according to organ systems, this revision features a thoroughly updated bibliography and discusses new drug-induced pathologies and applicable species comparisons to aid in the preclinical safety assessment of new medicines. This updated reference is essentia

Drugs - Toxicity testing. --- Drugs -- Toxicology. --- Laboratory animals - Histopathology. --- Laboratory animals -- Histopathology. --- Toxicity testing. --- Drugs --- Laboratory animals --- Medicine --- Drug Discovery --- Animal Population Groups --- Evaluation Studies as Topic --- Anatomy --- Investigative Techniques --- Animals --- Biological Science Disciplines --- Health Occupations --- Natural Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Disciplines and Occupations --- Eukaryota --- Organisms --- Drug Evaluation, Preclinical --- Pathology --- Animals, Laboratory --- Histology --- Public Health --- Health & Biological Sciences --- Toxicology & Public Health --- Toxicity testing --- Histopathology --- Laboratory Animals --- Animal, Laboratory --- Laboratory Animal --- Disease Models, Animal --- Biomedical Research --- Pathologies --- Disease --- Drug Evaluation Studies, Preclinical --- Drug Evaluations, Preclinical --- Evaluation Studies, Drug, Preclinical --- Evaluation, Preclinical Drug --- Evaluations, Preclinical Drug --- Medicinal Plants Testing, Preclinical --- Preclinical Drug Evaluation --- Preclinical Drug Evaluations --- Drug Screening --- Evaluation Studies, Drug, Pre-Clinical --- Drug Screenings --- Screening, Drug --- Screenings, Drug --- Eucarya --- Eukarya --- Eukaryotes --- Eukaryotas --- Eukaryote --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Health Professions --- Health Occupation --- Health Profession --- Profession, Health --- Professions, Health --- Occupations --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Animalia --- Animal --- Metazoa --- Investigative Technics --- Investigative Technic --- Investigative Technique --- Technic, Investigative --- Technics, Investigative --- Technique, Investigative --- Techniques, Investigative --- Anatomies --- Critique --- Evaluation Indexes --- Evaluation Methodology --- Evaluation Report --- Evaluation Research --- Methodology, Evaluation --- Pre-Post Tests --- Qualitative Evaluation --- Quantitative Evaluation --- Theoretical Effectiveness --- Use-Effectiveness --- Critiques --- Effectiveness, Theoretical --- Evaluation Methodologies --- Evaluation Reports --- Evaluation, Qualitative --- Evaluation, Quantitative --- Evaluations, Qualitative --- Evaluations, Quantitative --- Indexes, Evaluation --- Methodologies, Evaluation --- Pre Post Tests --- Pre-Post Test --- Qualitative Evaluations --- Quantitative Evaluations --- Report, Evaluation --- Reports, Evaluation --- Research, Evaluation --- Test, Pre-Post --- Tests, Pre-Post --- Use Effectiveness --- Animal Population Group --- Population Group, Animal --- Population Groups, Animal --- Zoology --- Drug Prospecting --- Discovery, Drug --- Prospecting, Drug --- High-Throughput Screening Assays --- Bioprospecting --- Medical Specialities --- Medical Specialties --- Medical Specialty --- Specialities, Medical --- Specialties, Medical --- Specialty, Medical --- Medical Speciality --- Speciality, Medical --- Health Workforce --- Animals, Experimental --- Animals in research --- Experimental animals --- Lab animals --- Animal culture --- Laboratory organisms --- Working animals --- Animal experimentation --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- pathology --- Vocations --- Occupation --- Vocation --- Occupational Groups --- Histopathology.