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Cells --- Transport Vesicles. --- Mechanical properties --- Mechanical properties. --- Cytology --- Espai extracel·lular --- Membranes cel·lulars --- Espai extracel·lular. --- Membranes cel·lulars.

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This book provides a detailed account of the physico-chemical properties and biological functions of the outer membrane vesicles (OMVs) of different pathogenic and non-pathogenic Gram-negative bacteria. It also includes an authentic record of the first systematic study that discovered the mechanism of OMV formation by a pathogen, Vibrio cholerae, and proposed that the process represented a novel secretory activity of bacteria. Furthermore, the authors present clinical and laboratory data on the use of OMVs as immunogens, as effective and licensed vaccines against Neisseria meningitidis serogroup B infections and on the development of more effective vaccines against other human and animal pathogens including Vibrio cholerae. This volume thus bears witness to the emerging revolution in the field of vaccines against pathogens and closes with a discussion of open questions and future research on OMVs.

Bacteria -- chemistry. --- Bacteria -- Physiology. --- Cellular signal transduction. --- Bacteria --- Cytoplasmic Vesicles --- Cellular Structures --- Biology --- Biological Science Disciplines --- Organisms --- Cells --- Organelles --- Natural Science Disciplines --- Disciplines and Occupations --- Cytoplasmic Structures --- Anatomy --- Cytoplasm --- Intracellular Space --- Transport Vesicles --- Microbiology --- Physiology --- Cell Membrane --- Health & Biological Sciences --- Microbiology & Immunology --- Ultrastructure --- Gram-negative bacteria. --- Cell membranes. --- Morphology. --- Physiology. --- Medicine. --- Immunology. --- Medical microbiology. --- Bacteriology. --- Biomedicine. --- Medical Microbiology. --- Membrane Biology. --- Cell surfaces --- Cytoplasmic membranes --- Plasma membranes --- Plasmalemma --- Membranes (Biology) --- Glycocalyces --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Microbiology. --- Microbial biology --- Microorganisms --- Cell membranes .

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For more than a decade, caveolin proteins have attracted a lot of attention in the field of cancer research. Additional roles besides maintaining the structural integrity of caveolae (meaning “little caves” in latin) have been attributed to these complex proteins. In fact, they have emerged as important regulators of cell signaling, proliferation, invasion and angiogenesis. The current book focuses on caveolin-1, the best-studied and well- characterized of all three caveolin family members (caveolin-1, -2 and -3). As such, the current chapters illustrate the roles of caveolin-1 in breast, prostate, skin, colon, brain and pancreatic cancers, and highlight its specific contribution to tumor growth through epithelial and stromal interactions, as well as its involvement in angiogenesis. This book summarizes the existing literature and provides interesting new perspectives on future advancement and therapeutic possibilities involving caveolins in cancer. This work brings together highly respected and experienced scientists in the field of caveolins who wrote informative chapters on the role of caveolin-1 in cancer in a format that conveys its role as both a tumor suppressor and tumor promoter. We invite you to read, enjoy and be part of these new promising discoveries that are rapidly advancing the field of cancer research.

Carcinogenesis. --- Carcinogenesis --- Adaptor Proteins, Signal Transducing --- Diseases --- Phosphoproteins --- Biological Markers --- Coated Pits, Cell-Membrane --- Membrane Microdomains --- Metabolic Phenomena --- Biological Science Disciplines --- Caveolins --- Biochemical Processes --- Medicine --- Coated Vesicles --- Cell Physiological Processes --- Health Occupations --- Intracellular Signaling Peptides and Proteins --- Carrier Proteins --- Phenomena and Processes --- Transport Vesicles --- Chemical Processes --- Biological Factors --- Cell Membrane Structures --- Vesicular Transport Proteins --- Cell Physiological Phenomena --- Natural Science Disciplines --- Biochemical Phenomena --- Proteins --- Chemical Phenomena --- Amino Acids, Peptides, and Proteins --- Disciplines and Occupations --- Chemicals and Drugs --- Cytoplasmic Vesicles --- Cell Membrane --- Membrane Proteins --- Peptides --- Cellular Structures --- Organelles --- Cells --- Cytoplasmic Structures --- Anatomy --- Cytoplasm --- Intracellular Space --- Caveolin 1 --- Caveolae --- Metabolism --- Physiology --- Signal Transduction --- Neoplasms --- Tumor Markers, Biological --- Pathology --- Health & Biological Sciences --- Oncology --- Cancer --- Prevention. --- Treatment. --- Cancer therapy --- Cancer treatment --- Oncogenesis --- Pathogenesis of cancer --- Tumorigenesis --- Therapy --- Pathogenesis --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Genetic toxicology --- Oncology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Physiological effect