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Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma.  The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data.  Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.

Oncology. Neoplasms --- oncologie --- Bone Neoplasms --- Biomarkers. --- Cytostatic Agents --- Diphosphonates --- Bones --- Bone metastasis --- Os --- Métastases osseuses --- prevention & control. --- secondary. --- therapeutic use. --- Cancer --- Prevention --- Prévention --- EPUB-LIV-FT LIVMEDEC SPRINGER-B

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Bone metastases continue to be a major cause of morbidity in cancer patients, but improved understanding of the biology of bone metastases has led to the identification of drugs that are of potential value in not only their treatment but also their prevention. This book, written by recognized experts in the field, provides a detailed overview of current knowledge on this subject. One important focus of the book is the efficacy of bisphosphonates in preventing bone metastases in patients with breast, lung, and prostate cancer and disease progression in cases of multiple myeloma.  The combined use of bisphosphonates and cytostatics is also discussed, with a report on first clinical data.  Further topics addressed include the significance of the bone microenvironment, special issues in the elderly patient, the use of bone turnover markers, and initial findings obtained with denosumab.

Bone Neoplasms -- diagnosis. --- Bone Neoplasms. --- Bones -- Cancer. --- Cancer -- Imaging. --- Bones --- Neoplasms by Site --- Biological Factors --- Organophosphorus Compounds --- Bone Diseases --- Noxae --- Musculoskeletal Diseases --- Chemicals and Drugs --- Neoplasms --- Organic Chemicals --- Toxic Actions --- Diseases --- Chemical Actions and Uses --- Bone Neoplasms --- Cytostatic Agents --- Biological Markers --- Diphosphonates --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Bone metastasis --- Prevention. --- Metastatic bone cancer --- Metastatic bone disease --- Osseous metastasis --- Skeletal metastasis --- Medicine. --- Oncology. --- Surgical oncology. --- Medicine & Public Health. --- Surgical Oncology. --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Tumors --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Excision --- Treatment --- Metastasis --- Oncology  . --- Cancer Therapy. --- Treatment. --- Cancer therapy --- Cancer treatment --- Therapy