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In Diabetes & C-Peptide: Scientific and Clinical Aspects, a renowned group of leading researchers and physicians offers a comprehensive overview of the role of C-Peptide in type 1 diabetes. The book is organized in five sections. An Introductory section provides the background and key features of C-peptide’s physiological function and how its deficiency contributes to complications. The second section describes up-to-date information on the biochemical and molecular actions of C-peptide, including membrane binding, interactions with insulin as well as the interaction between C-peptide and zinc and effects on microvascular vasoreactivity. The third section summarizes in vivo animal studies of the type 1 diabetic complications. The fourth section reviews the clinical efforts of C-peptide on inflammation, cardiovascular complication, neuropathy and nephropathy. Finally, in the Conclusions section, a summary of the present state of C-peptide, outstanding questions, and the likely direction of the field are offered. Developed by the foremost investigators in the rapidly moving field of C-peptide research, Diabetes & C-Peptide: Scientific and Clinical Aspects is an important contribution to the literature for all researchers and physicians concerned about type 1 diabetes.

C-peptide. --- Diabetes. --- Diabetes -- Complications. --- Diabetes --- C-peptide --- Diabetes Mellitus --- Proinsulin --- Therapeutics --- Autoimmune Diseases --- Biological Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Immune System Diseases --- Pancreatic Hormones --- Endocrine System Diseases --- Glucose Metabolism Disorders --- Natural Science Disciplines --- Peptide Hormones --- Diseases --- Disciplines and Occupations --- Metabolic Diseases --- Peptides --- Nutritional and Metabolic Diseases --- Hormones --- Hormones, Hormone Substitutes, and Hormone Antagonists --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Physiology --- Diabetes Mellitus, Type 1 --- Drug Therapy --- C-Peptide --- Diabetes Complications --- Medicine --- Health & Biological Sciences --- Clinical Endocrinology --- Complications --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Connecting peptide --- Medicine. --- Internal medicine. --- Endocrinology. --- Medicine & Public Health. --- Internal Medicine. --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Medicine, Internal --- Internal medicine --- Endocrinology .