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Plant bioactive compounds. --- Phytonutrients. --- Phytochemicals --- Plant bioactive compounds --- Bioactive compounds --- Plant products
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Plant bioactive compounds --- Plant biotechnology --- Medicinal plants --- Plant Extracts --- Fractionation
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Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developin
Plant bioactive compounds. --- Pharmaceutical chemistry. --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Chemistry --- Bioactive compounds --- Plant products
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In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful techniques and screening assays to identify the metabolic profiles and enzymes involved in drug metabolism. This book presents some in-depth reviews of selected topics in drug metabolism. Among the key topics covered are: the interplay between drug transport and metabolism in oral bioavailability; the influence of genetic and epigenetic factors on drug metabolism; impact of disease on transport and metabolism; and the use of novel microdosing techniques and novel LC/MS and genomic technologies to predict the metabolic parameters and profiles of potential new drug candidates.
Drugs. --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Toxicology and Pharmaceutical Science --- Pharmacokinetics --- Health Sciences
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Drugs --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Materia medica --- Pharmacology --- Pharmacy --- Research
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Bioactieve verbindingen --- Bioactive compounds --- Biologically active compounds --- Biomolécules -- Activité --- Biomolécules actives --- Composés bioactifs --- Compounds [Bioactive ] --- Compounds [Biologically active ] --- Compounds [Physiologically active ] --- Physiologically active compounds --- Principes actifs (Biochimie) --- Substances bioactives --- Theses --- Milk --- Composition --- Chemistry
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There are significant concerns regarding the potential side effects from the chronic use of conventional drugs such as corticosteroids, especially in children. Herbal therapy is less expensive, more readily available, and increasingly becoming common practice all over the world. Such practices have both their benefits and risks. However, herbal self-therapy might have serious health consequences due to incorrect self-diagnosis, inappropriate choice of herbal remedy or adulterated herbal product. In addition, absence of clinical trials and other traditional safety mechanisms before medicines are introduced to the wider market results in questionable safe dosage ranges which may produce adverse and unexpected outcomes. Therefore, the use of herbal remedies requires sufficient knowledge about the efficacy, safety and proper use of such products. Hence, it is necessary to have baseline data regarding the use of herbal remedies and to educate future health professionals about various aspects of herbal remedies.
Bioactive compounds. --- Pharmacology. --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemicals --- Chemotherapy --- Drugs --- Pharmacy --- Biologically active compounds --- Compounds, Bioactive --- Compounds, Biologically active --- Compounds, Physiologically active --- Physiologically active compounds --- Physiological effect --- Pharmacology
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The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure.
Bioactive compounds -- Synthesis. --- Chemistry. --- Palladium catalysts. --- Bioactive compounds --- Palladium catalysts --- Human Anatomy & Physiology --- Chemistry --- Health & Biological Sciences --- Physical Sciences & Mathematics --- Organic Chemistry --- Animal Biochemistry --- Synthesis --- Ring formation (Chemistry) --- Synthesis. --- Biologically active compounds --- Compounds, Bioactive --- Compounds, Biologically active --- Compounds, Physiologically active --- Physiologically active compounds --- Cyclization (Chemistry) --- Cycloaddition --- Exo-condensation --- Bioorganic chemistry. --- Catalysis. --- Bioorganic Chemistry. --- Chemical reactions --- Catalysts --- Chemicals --- Activation (Chemistry) --- Chemistry, Physical and theoretical --- Surface chemistry --- Bio-organic chemistry --- Biological organic chemistry --- Biochemistry --- Chemistry, Organic
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This book aims to bring together the areas of macroalgal taxonomy with strategies and methods used to characterise marine bioactive compounds. In addition, it looks at the importance of correct taxonomic characterization. It also describes applications of bioactive compounds from the marine environment and discusses how marine bioactive compounds represent a major market application in food and other industries. It provides examples of bioactive compounds isolated from marine resources. Examples are given as to how bioactive compounds have been used in functional food formulations and pharmaceutical applications, and how they alter biological activity to provide therapeutic benefits, nutritional values and health protection. It looks at the screening process for identification of bioactive molecules including computing methods for efficient in silico analysis, and describes different production methods used for bioactive compound isolation and identification. Furthermore, this book provides an insight into the market opportunities that exist for the identification and commercialization of new marine bioactive compounds. It also highlights regulations in the US, Europe, Japan and China regarding health or novel food claims for functional food products. .
Bioactive compounds. --- Marine pharmacology. --- Bioactive compounds --- Marine pharmacology --- Organism Forms --- Gram-Negative Oxygenic Photosynthetic Bacteria --- Foods, Specialized --- Bacteria --- Food --- Gram-Negative Bacteria --- Organisms --- Food and Beverages --- Technology, Industry, Agriculture --- Functional Food --- Seaweed --- Cyanobacteria --- Human Anatomy & Physiology --- Health & Biological Sciences --- Earth & Environmental Sciences --- Marine Science --- Pharmacy, Therapeutics, & Pharmacology --- Animal Biochemistry --- Drugs from the sea --- Marine pharmacognosy --- Materia medica, Marine --- Biologically active compounds --- Compounds, Bioactive --- Compounds, Biologically active --- Compounds, Physiologically active --- Physiologically active compounds --- Medicine. --- Pharmacy. --- Pharmaceutical technology. --- Bioorganic chemistry. --- Microbiology. --- Biomedicine. --- Pharmaceutical Sciences/Technology. --- Bioorganic Chemistry. --- Chemicals --- Marine biology --- Materia medica --- Pharmacognosy
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Drugs -- Cost effectiveness. --- Pharmacy -- Economic aspects. --- Drugs --- Pharmacy --- Cost effectiveness. --- Economic aspects. --- Medicaments --- Medications --- Medicine (Drugs) --- Medicines (Drugs) --- Pharmaceuticals --- Prescription drugs --- Chemistry --- Medicine --- Materia medica --- Pharmacology --- Bioactive compounds --- Medical supplies --- Pharmacopoeias --- Chemotherapy --- Decision making --- Cost effectiveness --- Economic aspects --- E-books --- Deciding --- Decision (Psychology) --- Decision analysis --- Decision processes --- Making decisions --- Management --- Management decisions --- Choice (Psychology) --- Problem solving
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