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Bioactive molecules in plant foods
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ISBN: 9781620815786 1620815788 9781620815151 162081515X Year: 2012 Publisher: Hauppauge, N.Y. : Nova Science Publishers,

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Book
Laboratory handbook for the fractionation of natural extracts
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ISBN: 1461376629 9781461376620 Year: 2012 Publisher: London: Springer,

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Book
Bioactive natural products
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ISBN: 981433538X 9789814335386 9814335371 9789814335379 Year: 2012 Publisher: Singapore Hackensack, N.J. World Scientific Pub. Co.

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Bioactive natural products are a rich source of novel therapeutics. Thus, the search for bioactive molecules from nature continues to play an important role in fashioning new medicinal agents. This volume, which comprises sixteen chapters written by active researchers and leading experts in natural products chemistry, brings together an overview of current discoveries in this remarkable field. It also provides information on the industrial application of natural products for medicinal purposes. This book will serve as a valuable resource for researchers to predict promising leads for developin


Book
Topics on Drug Metabolism
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ISBN: 9535143549 9535100998 Year: 2012 Publisher: IntechOpen

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In order to avoid late-stage drug failure due to factors such as undesirable metabolic instability, toxic metabolites, drug-drug interactions, and polymorphic metabolism, an enormous amount of effort has been expended by both the pharmaceutical industry and academia towards developing more powerful techniques and screening assays to identify the metabolic profiles and enzymes involved in drug metabolism. This book presents some in-depth reviews of selected topics in drug metabolism. Among the key topics covered are: the interplay between drug transport and metabolism in oral bioavailability; the influence of genetic and epigenetic factors on drug metabolism; impact of disease on transport and metabolism; and the use of novel microdosing techniques and novel LC/MS and genomic technologies to predict the metabolic parameters and profiles of potential new drug candidates.


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Encyclopedia of pharmacology research
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ISBN: 1614704058 9781614704058 9781614703839 1614703833 Year: 2012 Publisher: New York Nova Science Publishers

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Dissertation
Purification, analysis and applications of bioactive milk fat globule membrane material.
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ISBN: 9789059894976 Year: 2012 Publisher: Gent s.n.


Book
Bioactive Compounds in Phytomedicine
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ISBN: 9535166328 9533078057 Year: 2012 Publisher: IntechOpen

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There are significant concerns regarding the potential side effects from the chronic use of conventional drugs such as corticosteroids, especially in children. Herbal therapy is less expensive, more readily available, and increasingly becoming common practice all over the world. Such practices have both their benefits and risks. However, herbal self-therapy might have serious health consequences due to incorrect self-diagnosis, inappropriate choice of herbal remedy or adulterated herbal product. In addition, absence of clinical trials and other traditional safety mechanisms before medicines are introduced to the wider market results in questionable safe dosage ranges which may produce adverse and unexpected outcomes. Therefore, the use of herbal remedies requires sufficient knowledge about the efficacy, safety and proper use of such products. Hence, it is necessary to have baseline data regarding the use of herbal remedies and to educate future health professionals about various aspects of herbal remedies.


Book
Total synthesis of bioactive natural products by palladium-catalyzed domino cyclization of allenes and related compounds : doctoral thesis accepted by Kyoto University, Japan
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ISBN: 4431540423 9786613452665 1283452669 4431540431 Year: 2012 Publisher: Tokyo : Springer,

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The author has developed novel methodologies for highly efficient construction of functionalized heterocycles by palladium-catalyzed domino/cascade cyclization of allenes and related compounds containing appropriate nucleophilic group(s). Based on these methodologies, enantioselective total syntheses of bioactive natural products, pachastrissamine (26% overall yield in seven steps), lysergic acid (4.0% overall yield in fifteen steps), lysergol (3.6% overall yield in fifteen steps) and isolysergol (8.2% overall yield in eleven steps) have been achieved. These are more facile synthetic route than those previously reported. These findings would contribute to the development of efficient synthetic methods for biologically active compounds containing a complex structure.


Book
Marine bioactive compounds : sources, characterization and applications
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ISBN: 1461412463 9786613441096 1283441098 1461412471 Year: 2012 Publisher: New York : Springer,

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This book aims to bring together the areas of macroalgal taxonomy with strategies and methods used to characterise marine bioactive compounds. In addition, it looks at the importance of correct taxonomic characterization. It also describes applications of bioactive compounds from the marine environment and discusses how marine bioactive compounds represent a major market application in food and other industries.  It provides examples of bioactive compounds isolated from marine resources.   Examples are given as to how bioactive compounds have been used in functional food formulations and pharmaceutical applications, and how they alter biological activity to provide therapeutic benefits, nutritional values and health protection.   It looks at the screening process for identification of bioactive molecules including computing methods for efficient in silico analysis, and describes different production methods used for bioactive compound isolation and identification. Furthermore, this book provides an insight into the market opportunities that exist for the identification and commercialization of new marine bioactive compounds.  It also highlights regulations in the US, Europe, Japan and China regarding health or novel food claims for functional food products.   .


Book
Pharmacoeconomics
Authors: ---
ISBN: 8897419372 8897419380 9788897419389 9788897419372 Year: 2012 Publisher: Torino, Italy

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