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Cardiomyopathy means "heart (cardio) muscle (myo) disease (pathy)". Currently, cardiomyopathies are defined as myocardial disorders in which the heart muscle is structurally and/or functionally abnormal in the absence of a coronary artery disease, hypertension, valvular heart disease or congenital heart disease sufficient to cause the observed myocardial abnormalities. This book provides a comprehensive, state-of-the-art review of the current knowledge of cardiomyopathies. Instead of following the classic interdisciplinary division, the entire cardiovascular system is presented as a functional unity, and the contributors explore pathophysiological mechanisms from different perspectives, including genetics, molecular biology, electrophysiology, invasive and non-invasive cardiology, imaging methods and surgery. In order to provide a balanced medical view, this book was edited by a clinical cardiologist.
Myocardium --- Diseases. --- Cardiomyopathies --- Cardiomyopathy --- Myocardial diseases --- Myocardiopathies --- Myocardiopathy --- Cardiovascular medicine
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Hypertension. --- Heart --- Blood pressure --- Systolic blood pressure. --- Systolic pressure --- Regulation of blood pressure --- Biological control systems --- Baroreceptors --- Renin-angiotensin system --- Contraction of the heart --- Heart contraction --- Myocardial contraction --- Myocardium --- Systole (Cardiology) --- Systolic time interval --- Heart beat --- Blood pressure, High --- High blood pressure --- Vascular hypertension --- Blood circulation disorders --- Contraction. --- Regulation. --- Contraction
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Heart --- Chest --- Cardiac Surgical Procedures. --- Thoracic Surgery. --- Surgery --- Surgery. --- Cardiac surgery --- Open-heart surgery --- Thoracic surgery --- Surgery, Cardiac --- Surgery, Heart --- Surgery, Thoracic --- Cardiac Surgery --- Heart Surgery --- Cardiac Surgical Procedure --- Heart Surgical Procedure --- Heart Surgical Procedures --- Procedure, Cardiac Surgical --- Procedure, Heart Surgical --- Procedures, Cardiac Surgical --- Procedures, Heart Surgical --- Surgical Procedure, Cardiac --- Surgical Procedure, Heart --- Surgical Procedures, Cardiac --- Surgical Procedures, Heart --- Myocardium --- Thorax, Human --- Diseases --- surgery --- Thoracic surgeons --- Cardiac Surgical Procedures --- Cardiovascular Surgical Procedures --- Thorax --- Thoracic Surgical Procedures --- Thoracic Surgery --- Thorax (Zoology) --- Viscera --- Cardiopulmonary system --- Cardiovascular system --- Surgery - General and By Type
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Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. Importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. A special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. The chapters are written by experts from diverse clinical and biomedical research backgrounds. Translational Cardiology: Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.
Cardiology. --- Cardiovascular physiology. --- Pathophysiology. --- Cardiology --- Heart --- Cardiovascular Diseases --- Muscle, Striated --- Metabolic Phenomena --- Muscles --- Drug Therapy --- Phenomena and Processes --- Therapeutics --- Cardiovascular System --- Diseases --- Musculoskeletal System --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Anatomy --- Tissues --- Myocardium --- Heart Diseases --- Metabolism --- Molecular Targeted Therapy --- Medicine --- Health & Biological Sciences --- Pathology --- Molecular aspects --- Molecular aspects. --- Cardiology, Molecular --- Molecular cardiology --- Molecular biology --- Medicine. --- Molecular biology. --- Pathology. --- Medicine & Public Health. --- Molecular Medicine. --- Internal medicine --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Physicians --- Disease (Pathology) --- Medicine, Preventive --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology
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Calcium is crucial in governing contractile activities of myofilaments in cardiomyocytes, any defeats in calcium homeostasis of the cells would adversely affect heart pumping action. The characterization of calcium handling properties in human induced pluripotent stem cell-derived cardiomyocytes (iPS-CMCs) is of significant interest and pertinent to the stem cell and cardiac regenerative field because of their potential patient-specific therapeutic use.
Calcium -- Physiological effect. --- Cardiology. --- Cytology. --- Heart cells. --- Stem cells. --- Heart cells --- Stem cells --- Calcium --- Blood Coagulation Factors --- Metals, Alkaline Earth --- Myocardium --- Adult Stem Cells --- Metabolic Phenomena --- Muscle Cells --- Pluripotent Stem Cells --- Biological Factors --- Phenomena and Processes --- Stem Cells --- Elements --- Heart --- Muscle, Striated --- Metals --- Cells --- Inorganic Chemicals --- Cardiovascular System --- Chemicals and Drugs --- Anatomy --- Muscles --- Tissues --- Induced Pluripotent Stem Cells --- Myocytes, Cardiac --- Metabolism --- Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Cytology --- Physiological effect --- Metabolism. --- Cardiac cells --- Cardiocytes --- Cardiomyocytes --- Calcium metabolism --- Life sciences. --- Cell biology. --- Life Sciences. --- Stem Cells. --- Cell Biology. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cell biology --- Cellular biology --- Cytologists --- Internal medicine --- Biosciences --- Sciences, Life --- Science --- Diseases
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Coronary heart disease --- Heart --- Heart Diseases. --- Cardiac Surgical Procedures. --- Surgery --- Diseases --- Treatment --- Surgery. --- Treatment. --- Ukraine. --- Cardiac Surgical Procedure --- Heart Surgical Procedure --- Heart Surgical Procedures --- Procedure, Cardiac Surgical --- Procedure, Heart Surgical --- Procedures, Cardiac Surgical --- Procedures, Heart Surgical --- Surgical Procedure, Cardiac --- Surgical Procedure, Heart --- Surgical Procedures, Cardiac --- Surgical Procedures, Heart --- Myocardium --- Thoracic Surgery --- Cardiac Diseases --- Cardiac Disorders --- Heart Disorders --- Cardiac Disease --- Cardiac Disorder --- Heart Disease --- Heart Disorder --- Cardiology --- Cardiopulmonary system --- Cardiovascular system --- Chest --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Type A behavior --- surgery
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