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Essentials of functional MRI
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ISBN: 9781439818787 Year: 2011 Publisher: Boca Raton : Taylor & Francis,

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"During the last two decades, new developments in functional MRI (magnetic resonance imaging) have made it possible to detect changes in the brain over time, as opposed to the "snapshot" produced by conventional MRI. Essentials of Functional MRI breaks down the technical challenges for physicians, researchers, and technologists who use functional MRI but may not be experts in the necessary math and physics. The author describes the theory and practical details of functional MRI (fMRI) methodology, including how to acquire and analyze images, and a wide range of examples demonstrate how fMRI has been used thus far. The author provides the essential information to study, understand, use, and teach the practical aspects of fMRI for those people who are most likely to extend its use into clinical practice"--Provided by publisher.


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Fetal MRI
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ISBN: 9783540732709 3540732705 Year: 2011 Publisher: New York ; London : Springer,

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Electron cyclotron emission and electron cyclotron resonance heating (EC-16) : proceedings of the 16th Joint Workshop : Sanya, China, 12-15 April 2010
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ISBN: 1283148714 9786613148711 9814340278 9789814340274 9789814340267 981434026X Year: 2011 Publisher: Hackensack, N.J. : World Scientific,

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This proceedings volume, the sixteenth in a biannual series, presents a snapshot of the state of current research worldwide on Electron Cyclotron Emission (ECE) and Electron Cyclotron Resonance Heating (ECRH) and related technologies. The papers address the physics, both theory and experiment, of ECE and ECRH. The technologies of high power millimeter-wave sources - gyrotrons - and transmission lines and launchers are included. The focus is on physics and technology relevant to the research and development of nuclear fusion.


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Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies
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Year: 2011 Publisher: [Place of publication not identified] : InTechOpen,

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Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While normal tissue oxygenation is around 40 mm Hg, both rodent and human tumors possess regions of tissue oxygenation below 10 mm Hg, at which tumor cells become increasingly resistant to radiation damage (radiobiological hypoxia) (Gray, 1953). Because of this so-called "oxygen enhancement effect", the radiation dose required to achieve the same biologic effect is about three times higher in the absence of oxygen than in the presence of normal levels of oxygen (Gray et al., 1953; Horsman & van der Kogel, 2009). Hypoxic tumor cells, which are therefore more resistant to radiotherapy than well oxygenated ones, remain clonogenic and contribute to the therapeutic outcome of fractionated radiotherapy (Rojas et al., 1992).


Book
Chapter 13 Targeting Tumor Perfusion and Oxygenation Modulates Hypoxia and Cancer Sensitivity to Radiotherapy and Systemic Therapies
Authors: ---
Year: 2011 Publisher: [Place of publication not identified] : InTechOpen,

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Abstract

Hypoxia, a partial pressure of oxygen (pO2) below physiological needs, is a limiting factor affecting the efficiency of radiotherapy. Indeed, the reaction of reactive oxygen species (ROS, produced by water radiolysis) with DNA is readily reversible unless oxygen stabilizes the DNA lesion. While normal tissue oxygenation is around 40 mm Hg, both rodent and human tumors possess regions of tissue oxygenation below 10 mm Hg, at which tumor cells become increasingly resistant to radiation damage (radiobiological hypoxia) (Gray, 1953). Because of this so-called "oxygen enhancement effect", the radiation dose required to achieve the same biologic effect is about three times higher in the absence of oxygen than in the presence of normal levels of oxygen (Gray et al., 1953; Horsman & van der Kogel, 2009). Hypoxic tumor cells, which are therefore more resistant to radiotherapy than well oxygenated ones, remain clonogenic and contribute to the therapeutic outcome of fractionated radiotherapy (Rojas et al., 1992).


Book
Body MR imaging at 3 Tesla
Authors: ---
ISBN: 1139088661 1107214475 1280775947 113909243X 9786613686336 1139091034 1139091921 0511978960 Year: 2011 Publisher: Cambridge : Cambridge University Press,

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Body MR Imaging at 3.0 Tesla is a practical text enabling radiologists to maximise the benefits of high field 3T MR systems in a range of body applications. It explains the physical principles of MR imaging using 3T magnets, and the differences between 1.5T and 3T when applied extracranially. The book's organ-based approach focuses on optimized techniques, providing recommended protocols for the main vendors of 3T MRI systems. All major thoracic and abdominal organs are covered, including breast, heart, liver, pancreas, the GI tract, kidneys, prostate and female pelvic organs. Abdominal and pelvic MR angiography and MRCP are also discussed. Protocol optimization, appearance of artifacts and novel applications using 3T are emphasized. Written and edited by experts in the field, Body MR Imaging at 3.0 Tesla guides radiologists in optimizing imaging protocols for 3T MR systems, reducing artifacts and identifying the advantages of using 3T in body applications.


Book
Extra-cranial applications of diffusion-weighted MRI
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ISBN: 0511851146 1107216117 128281799X 9786612817991 0511908938 0511908199 0511909705 0511906900 0511778074 0511905629 Year: 2011 Publisher: Cambridge : Cambridge University Press,

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Continuous improvement in MRI technology in recent years has led to the application of diffusion-weighted MR imaging in organ systems outside the brain. Extra-Cranial Applications of Diffusion-Weighted MRI provides an extensive review of current and future applications of this imaging modality by world-renowned experts. Organized by organ system, each chapter is highly illustrated, offering a balance of protocols, illustrations and principles of image interpretation. An initial chapter provides an overview of relevant physics and other technical details, followed by detailed chapters on all major body systems including liver, kidney, prostate, breast and spine. A final chapter discusses assessment of therapy response. Written and edited by leading DW-MRI experts worldwide, Extra-Cranial Applications of Diffusion-Weighted MRI is an invaluable resource for radiology trainees, practising radiologists and for researchers in a wide variety of disciplines.


Book
Extra-cranial applications of diffusion-weighted MRI
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ISBN: 9780521518697 Year: 2011 Publisher: Cambridge : Cambridge University Press,

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"Continuous improvement in MRI technology in recent years has led to the application of diffusion-weighted MR imaging in organ systems outside the brain. Extra-Cranial Applications of Diffusion-Weighted MRI provides an extensive review of current and future applications of this imaging modality by world-renowned experts. Organized by organ system, each chapter is highly illustrated, offering a balance of protocols, illustrations and principles of image interpretation. An initial chapter provides an overview of relevant physics and other technical details, followed by detailed chapters on all major body systems including liver, kidney, prostate, breast and spine. A final chapter discusses assessment of therapy response. Written and edited by leading DW-MRI experts worldwide, Extra-Cranial Applications of Diffusion-Weighted MRI is an invaluable resource for radiology trainees, practising radiologists and for researchers in a wide variety of disciplines"--Provided by publisher.


Book
Diffusion MRI : theory, methods, and application
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ISBN: 0199965145 1282953125 9786612953125 0199708703 9780199708703 9780195369779 0195369777 9780199965144 9781282953123 6612953128 Year: 2011 Publisher: New York : Oxford University Press,

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Since its initial development in the mid-1980's, and wide accessibility to perform diffusion MRI on all MRI scanners, the use of diffusion MRI has exploded. Nearly every MRI centre carries out diffusion MRI of some kind. Obtaining good quality diffusion MRI and making sound and robust inferences from the data is not trivial, however, and involves a long chain of events from ensuring that the hardware is performing optimally, the pulse sequence is carefully designed, the acquisition is optimal, the data quality is maximized while artifacts are minimized, the appropriate post-processing is used,

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