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Electrospinning is a simple and highly versatile method for generating ultrathin fibres with diameters ranging from a few micrometres to tens of nanometres. Although most commonly associated with textile manufacturing, recent research has proved that the electrospinning technology can be used to create organ components and repair damaged tissues. Electrospinning for tissue regeneration provides a comprehensive overview of this innovative approach to tissue repair and regeneration and examines how it is being employed within the biomaterials sector.The book opens with an introduction to
Electrospinning. --- Guided tissue regeneration. --- Tissue engineering -- Methods. --- Tissue engineering. --- Tissue engineering --- Electrospinning --- Investigative Techniques --- Reconstructive Surgical Procedures --- Culture Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Clinical Laboratory Techniques --- Surgical Procedures, Operative --- Guided Tissue Regeneration --- Methods --- Tissue Engineering --- Health & Biological Sciences --- Biomedical Engineering --- Guided Tissue Regeneration. --- methods. --- Spinning --- Biomedical engineering --- Regenerative medicine --- Tissue culture
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The development and application of bioactive nano-structured constructs for tissue regeneration is the focus of the research summarised in this thesis. Moreover, a particular focus is the rational use of supercritical carbon dioxide foaming and electrospinning technologies which can lead to innovative polymeric bioresorbable scaffolds made of hydrolysable (both commercial and ‘ad-hoc’ synthesized) polyesters. Mainly, the author discusses the manipulation of polymer chemical structure and composition to tune scaffold physical properties, and optimization of scaffold 3D architecture by a smart use of both fabrication techniques. The multidisciplinary nature of this research is imperative in pursuing the challenge of tissue regeneration successfully. One of the strengths of this thesis is the integration of knowledge from chemistry, physics, engineering, materials science and biomedical science which has contributed to setting up new national and international collaborations, while strengthening existing ones.
Biomedical engineering. --- Biomedical materials. --- Bone regeneration. --- Cartilage -- Regeneration. --- Tissue Engineering. --- Chemistry --- Physical Sciences & Mathematics --- Organic Chemistry --- Tissue engineering. --- Tissue scaffolds. --- Scaffolding, Tissue --- Scaffolds, Tissue --- Tissue scaffolding --- Chemistry. --- Polymers. --- Biomaterials. --- Polymer Sciences. --- Biomedical Engineering. --- Guided tissue regeneration --- Tissue engineering --- Biomedical engineering --- Regenerative medicine --- Tissue culture --- Equipment and supplies --- Biomedical Engineering and Bioengineering. --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Biocompatible materials --- Biomaterials --- Medical materials --- Materials --- Biocompatibility --- Prosthesis --- Polymere --- Polymeride --- Polymers and polymerization --- Macromolecules --- Polymers . --- Bioartificial materials --- Hemocompatible materials --- Biomaterials (Biomedical materials)
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Active implants are drug or protein-eluting implants that induce healing effects, in addition to their regular task, for example support. This effect is achieved by controlled release of bioactive agents to the surrounding tissue. This book presents a broad overview of biomaterial platforms used in internal and external drug-eluting implants. The book is divided into four parts: 1. Drug-eluting implants 2. Scaffolds for bone regeneration 3. Scaffolds based on natural polymers 4. New polymeric systems for active implants The 18 reviews describe active implants in terms of matrix formats, incorporated drugs and their release profiles from the implants, as well as cell-implant interactions and functions. The effect of the process parameters on the micro or nano-structure and on the resulting drug release profiles, mechanical and physical properties, and other relevant properties, are emphasized. It is the first book to describe a broad range of active implants and present the frontier of knowledge in this field. The new biomaterial approaches for active implants described in this book enhance the tools available for clinically important biomedical applications.
Tissue engineering. --- Biomedical and Dental Materials --- Culture Media --- Reconstructive Surgical Procedures --- Prostheses and Implants --- Culture Techniques --- Equipment and Supplies --- Clinical Laboratory Techniques --- Manufactured Materials --- Chemicals and Drugs --- Specialty Uses of Chemicals --- Surgical Procedures, Operative --- Technology, Industry, and Agriculture --- Investigative Techniques --- Chemical Actions and Uses --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Technology, Industry, Agriculture --- Guided Tissue Regeneration --- Biocompatible Materials --- Absorbable Implants --- Tissue Scaffolds --- Tissue Engineering --- Surgery & Anesthesiology --- Health & Biological Sciences --- Biomedical Engineering --- Prosthesis & Artificial Organs --- Guided tissue regeneration --- Tissue scaffolds. --- Tissue-integrated prostheses. --- Equipment and supplies. --- Tissue-integrated implants --- Tissue-integrated prosthesis --- Scaffolding, Tissue --- Scaffolds, Tissue --- Tissue scaffolding --- Engineering. --- Molecular biology. --- Medicinal chemistry. --- Medical biochemistry. --- Biomedical engineering. --- Biomaterials. --- Biomedical Engineering. --- Molecular Medicine. --- Medical Biochemistry. --- Medicinal Chemistry. --- Prosthesis --- Osseointegration --- Tissue engineering --- Equipment and supplies --- Medicine. --- Biochemistry. --- Biomedical Engineering and Bioengineering. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Biocompatible materials --- Biomaterials --- Medical materials --- Medicine --- Biomedical engineering --- Materials --- Biocompatibility --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Composition --- Health Workforce --- Bioartificial materials --- Hemocompatible materials --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry --- Molecular biochemistry --- Molecular biophysics --- Biomolecules --- Systems biology --- Biomaterials (Biomedical materials)
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