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The ability to grow stem cells in the laboratory and to guide their maturation to functional cells allows us to study the underlying mechanisms that govern vasculature differentiation and assembly in health and disease. Accumulating evidence suggests that early stages of vascular growth are exquisitely tuned by biophysical cues from the microenvironment, yet the scientific understanding of such cellular environments is still in its infancy. Comprehending these processes sufficiently to manipulate them would pave the way to controlling blood vessel growth in therapeutic applications. This book assembles the works and views of experts from various disciplines to provide a unique perspective on how different aspects of its microenvironment regulate the differentiation and assembly of the vasculature. In particular, it describes recent efforts to exploit modern engineering techniques to study and manipulate various biophysical cues. Biophysical Regulation of Vascular Differentiation and Assembly provides an interdisciplinary view of vasculature regulation by various biophysical cues and presents recent advances in measuring and controlling such parameters. This book will be of interest to biologists, biophysicists and engineers who work with vascular differentiation and assembly.

Biomedical engineering. --- Biophysics. --- Blood-vessels -- Growth -- Regulation. --- Blood-vessels -- Growth. --- Cell differentiation. --- Neovascularization -- Regulation. --- Stem cells. --- Stem cells --- Blood-vessels --- Biophysics --- Biomedical engineering --- Neovascularization --- Cell differentiation --- Physics --- Engineering --- Cardiovascular System --- Cell Physiological Processes --- Biological Science Disciplines --- Cells --- Health Occupations --- Technology, Industry, and Agriculture --- Disciplines and Occupations --- Anatomy --- Natural Science Disciplines --- Cell Physiological Phenomena --- Technology, Industry, Agriculture --- Phenomena and Processes --- Biomedical Engineering --- Cell Differentiation --- Stem Cells --- Blood Vessels --- Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Physiology --- Cytology --- Growth --- Regulation --- Biological control systems. --- Growth. --- Biocybernetics --- Biofeedback --- Biological cybernetics --- Biological regulation --- Control biophysics --- Control systems, Biological --- Control theory in biology --- Regulation, Biological --- Biological physics --- Physics. --- Biological physics. --- Biophysics and Biological Physics. --- Biomedical Engineering. --- Stem Cells. --- Medical sciences --- Biological systems --- Control theory --- Cybernetics --- Feedback control systems --- Nervous system --- Biological and Medical Physics, Biophysics. --- Biomedical Engineering and Bioengineering. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Clinical engineering --- Medical engineering --- Bioengineering --- Medicine