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Stem cell biology has drawn tremendous interest in recent years as it promises cures for a variety of incurable diseases. This book deals with the basic and clinical aspects of stem cell research and involves work on the full spectrum of stem cells isolated today. It also covers the conversion of stem cell types into a variety of useful tissues which may be used in the future for transplantation therapy. It is thus aimed at undergraduates, postgraduates, scientists, embryologists, doctors, tissue engineers and anyone who wishes to gain some insight into stem cell biology. This book is importan
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Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves
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Par ordre hierarchique decroissant, l'espece, l'individu et la lignee germinale representent les trois entites qui conditionnent l'aptitude des etres humains a procreer et a assurer par la-meme la survie de l'espece. La rencontre des cellules sexuelles, dterminante pour la gense d'un nouvel individu, est un processus qui apparat de plus en plus complexe et dont la finalit s'est largie. Il ne s'agit plus seulement de la transmission des gnomes parentaux l'A uf fcond mais aussi du transfert de marques dites pigntiques susceptibles d'influencer le dveloppement de l'embryon.La transgression des lois naturelles de la reproduction qui est reste longtemps de l'ordre de l'imaginaire est devenue une ralit biologique dans la seconde moiti du XXe sicle. Les procrations mdicalement assistes et le clonage animal, raliss avec succs au terme d'une longue exploration scientifique, en ont t les deux vnements marquants.Les cellules souches germinales, cultives au laboratoire, font preuve d'une tonnante plasticit. Elles suscitent, en particulier chez l'homme, de nouveaux espoirs thrapeutiques. Dans le droit fil de l'exprimentation animale, peut-on imaginer de transplanter des cellules de la ligne germinale pour remdier l'incapacit des gonades produire des cellules sexuelles ?Les avances dans la connaissance des cellules sexuelles ne concernent pas uniquement le biologiste et le mdecin. Elles sont source de questionnement pour le philosophe.
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In the past decades our understanding of stem cell biology has increased tremendously. Many types of stem cells have been discovered in tissues of which everyone presumed were unable to regenerate in adults; these include particularly the heart and the brain. There is vast interest in stem cells from biologists and clinicians who see the potential for regenerative medicine and future treatments for chronic diseases like Parkinson, diabetes and spinal cord lesions based on the use of stem cells and entrepreneurs in biotechnology who expect new commercial applications ranging from drug discov
Stem cells. --- Embryonic stem cells. --- Embryonal stem cells --- Stem cells --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells
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This is a comprehensive review of the current state of stem cell bioengineering from authorities in the field. The first part of the book includes the basic research work on stem cells and bioengineering carried out by various laboratories. The second part consists of a review of the current development of various microcapsules in stem cell therapy. The last part will summarize the overall clinical trials on stem cell therapy and myocardial regeneration as well as the most updated personal experience recently completed by well-known experts in this field.
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For many years, the ethical discussion surrounding human embryonic stem cell research has focused on the moral status of the embryo. This text takes a wider moral berth and focuses on numerous ethical, legal and social aspects involved in translating the results of stem cell research into diagnostic and therapeutic applications. "Translational Stem Cell Research" is broken into ten sections. It opens with an overview of the latest in stem cell research, focusing on specific diseases and the treatment of burn victims. Part II discusses the issues involved in the many steps from bench to bedside, ranging from first research in vitro to clinical trials. Part III covers scientific, regulatory and ethical challenges to basic research, and Part IV details issues regarding stem cell banks. Part V explores ethical, economic and strategic issues involved in collaboration between universities and industry, and Part VI addresses legal problems raised by patents on human stem-cell based inventions plus the extent to which there can be technological solutions to a moral dilemma.Part VII presents imaginative ways of communicating research to the general public and how to create conditions for a constructive dialogue. Part VIII probes psychosocial and cultural factors affecting judgment and decisions about translational stem cell research, and Part IX explores problems and procedures raised by an examination of the evaluation of stem cell research projects in research ethics committees. The book closes with a look into the future of translational stem cell research and stem cell-based therapeutic applications.
Stem cells --- Stem cells --- Stem cells --- Stem cells --- Government policy --- Moral and ethical aspects --- Research --- Therapeutic use
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Pluripotent stem cells have the potential to revolutionise medicine, providing treatment options for a wide range of diseases and conditions that currently lack therapies or cures. This book describes methodological advances in the culture and manipulation of embryonic stem cells that will serve to bring this promise to practice.
Embryonic stem cells. --- Embryonal stem cells --- Stem cells --- Cellular biology (cytology)
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Stem cells --- Stem cells. --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- stamcellen --- Cytology
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Stem cells. --- Stem cells --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Cells --- Therapeutic use.
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