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The LNCS journal Transactions on Large-Scale Data- and Knowledge-Centered Systems focuses on data management, knowledge discovery, and knowledge processing, which are core and hot topics in computer science. Since the 1990s, the Internet has become the main driving force behind application development in all domains. An increase in the demand for resource sharing across different sites connected through networks has led to an evolution of data- and knowledge-management systems from centralized systems to decentralized systems enabling large-scale distributed applications providing high scalability. Current decentralized systems still focus on data and knowledge as their main resource. Feasibility of these systems relies basically on P2P (peer-to-peer) techniques and the support of agent systems with scaling and decentralized control. Synergy between Grids, P2P systems, and agent technologies is the key to data- and knowledge-centered systems in large-scale environments. This, the third issue of Transactions on Large-Scale Data- and Knowledge-Centered Systems, contains two kinds of papers: Firstly, a selection of the best papers from the third International Conference on Data Management in Grid and Peer-to-Peer Systems, Globe 2010, and secondly, a selection of 6 papers from the 18 papers submitted in response to the call for papers for this issue. The topics covered by this special issue include replication, the semantic web, information retrieval, data storage, source selection, and large-scale distributed applications.

Transaction systems (Computer systems) --- Database management --- Expert systems (Computer science) --- Peer-to-peer architecture (Computer networks) --- Engineering & Applied Sciences --- Computer Science --- Database management. --- P2P (Computer network architecture) --- Knowledge-based systems (Computer science) --- Systems, Expert (Computer science) --- Data base management --- Data services (Database management) --- Database management services --- DBMS (Computer science) --- Generalized data management systems --- Services, Database management --- Systems, Database management --- Systems, Generalized database management --- Computer science. --- Data structures (Computer science). --- Data mining. --- Information storage and retrieval. --- Computer Science. --- Database Management. --- Data Mining and Knowledge Discovery. --- Information Storage and Retrieval. --- Information Systems Applications (incl. Internet). --- Data Structures. --- Data Storage Representation. --- Electronic data processing --- Algorithmic knowledge discovery --- Factual data analysis --- KDD (Information retrieval) --- Knowledge discovery in data --- Knowledge discovery in databases --- Mining, Data --- Database searching --- Information structures (Computer science) --- Structures, Data (Computer science) --- Structures, Information (Computer science) --- File organization (Computer science) --- Abstract data types (Computer science) --- Informatics --- Science --- Computer network architectures --- Artificial intelligence --- Computer systems --- Soft computing --- Information storage and retrieva. --- Data structures (Computer scienc. --- Information storage and retrieval systems. --- Automatic data storage --- Automatic information retrieval --- Automation in documentation --- Computer-based information systems --- Data processing systems --- Data storage and retrieval systems --- Discovery systems, Information --- Information discovery systems --- Information processing systems --- Information retrieval systems --- Machine data storage and retrieval --- Mechanized information storage and retrieval systems --- Electronic information resources --- Data libraries --- Digital libraries --- Information organization --- Information retrieval --- Data structures (Computer science) --- Application software. --- Application computer programs --- Application computer software --- Applications software --- Apps (Computer software) --- Computer software --- Information retrieval. --- Computer architecture. --- Computer and Information Systems Applications. --- Data Science. --- Data processing. --- Architecture, Computer --- Data retrieval --- Data storage --- Discovery, Information --- Information discovery --- Information storage and retrieval --- Retrieval of information --- Documentation --- Information science --- Information storage and retrieval systems --- Data centers