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2011 (2)

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Book
Computational Mechanisms of Au and Pt Catalyzed Reactions
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ISBN: 3642210821 364221083X 9783642210822 Year: 2011 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Abstract

Structure, Bonding, and Reactivity of Reactant Complexes and Key Intermediates, by Elena Soriano and José Marco-Contelles.- Cycloisomerization of 1,n-Enynes Via Carbophilic Activation, by Patrick Yves Toullec and Véronique Michelet.- DFT-Based Mechanistic Insights into Noble Metal-Catalyzed Rearrangement of Propargylic Derivatives: Chirality Transfer Processes, by Olalla Nieto Faza and Angel R. de Lera.- N-Heterocyclic Carbene Complexes of Au, Pd, and Pt as Effective Catalysts in Organic Synthesis, by Andrea Correa, Steven P. Nolan and Luigi Cavallo.- Activation of Allenes by Gold Complexes: A Theoretical Standpoint, by Max Malacria, Louis Fensterbank and Vincent Gandon.- Heterocyclization of Allenes Catalyzed by Late Transition Metals: Mechanisms and Regioselectivity, by Benito Alcaide, Pedro Almendros, Teresa Martínez del Campo, Elena Soriano and José Marco-Contelles.- Gold-Catalyzed Cycloadditions Involving Allenes: Mechanistic Insights from Theoretical Studies, by Sergi Montserrat, Gregori Ujaque, Fernando López, José L. Mascareñas and Agustí Lledós.-     .


Book
Metallointercalators : Synthesis and Techniques to Probe Their Interactions with Biomolecules
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ISBN: 3709116694 321109427X 3211990798 Year: 2011 Publisher: Vienna : Springer Vienna : Imprint: Springer,

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Abstract

A comprehensive treatment of the characterisation techniques used in investigating inorganic and organic molecules that interact with biomolecules is presented to the reader in a clear fashion. The work consists of two parts: (i) synthetic aspects of metallointercalators along with targeting and improving transport and (ii) the various techniques that are used for probing their interactions, such as; DNA-NMR, PGSE-NMR, DNA ESI-MS, Linear and Circular Dichroism, Fluorescence Spectroscopy, Confocal Microscopy, Viscosity, TGA and dialysis, Microarrays, biological analysis. Chapters are devoted to the synthesis and the techniques used to study the interactions of inorganic complexes with biomolecules. Considerably detailed examples are used to help illustrate the application of these techniques. This book is a useful resource for an array of inorganic and organic advanced undergraduate and graduate courses and for researchers in drug discovery.

Keywords

Biochemistry. --- Chemistry, Inorganic. --- Chemistry, Organic. --- DNA replication. --- DNA-ligand interactions --- Clathrate compounds --- Transition metal complexes --- Genetic regulation --- Organic Chemicals --- Spectrum Analysis --- Indicators and Reagents --- Inorganic Chemicals --- Natural Science Disciplines --- Laboratory Chemicals --- Chemicals and Drugs --- Disciplines and Occupations --- Chemistry Techniques, Analytical --- Specialty Uses of Chemicals --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Chemical Actions and Uses --- Organometallic Compounds --- Chemistry --- Magnetic Resonance Spectroscopy --- Intercalating Agents --- Human Anatomy & Physiology --- Physical Sciences & Mathematics --- Health & Biological Sciences --- Inorganic Chemistry --- Animal Biochemistry --- Clathrate compounds. --- Cage inclusion compounds --- Clathrate inclusion compounds --- Clathrates --- Intercalation compounds --- Chemistry. --- Pharmacy. --- Spectroscopy. --- Inorganic chemistry. --- Physical chemistry. --- Inorganic Chemistry. --- Biochemistry, general. --- Physical Chemistry. --- Spectroscopy/Spectrometry. --- Complex compounds --- Molecular sieves --- Chemistry, inorganic. --- Chemistry, Physical organic. --- Analysis, Spectrum --- Spectra --- Spectrochemical analysis --- Spectrochemistry --- Spectroscopy --- Chemistry, Analytic --- Interferometry --- Optics --- Radiation --- Wave-motion, Theory of --- Absorption spectra --- Light --- Spectroscope --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Medicine --- Drugs --- Materia medica --- Pharmacology --- Inorganic chemistry --- Inorganic compounds --- Qualitative --- Composition --- Spectrometry --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Analytical chemistry

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