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The genetics science is less than 150 years old, but its accomplishments have been astonishing. Genetics has become an indispensable component of almost all research in modern biology and medicine. Human genetic variation is associated with many, if not all, human diseases and disabilities. Nowadays, studies investigating any biological process, from the molecular level to the population level, use the "genetic approach" to gain understanding of that process. This book contains many diverse chapters, dealing with human genetic diseases, methods to diagnose them, novel approaches to treat them and molecular approaches and concepts to understand them. Although this book does not give a comprehensive overview of human genetic diseases, I believe that the sixteen book chapters will be a valuable resource for researchers and students in different life and medical sciences.
Genetic disorders. --- Congenital diseases --- Disorders, Genetic --- Disorders, Inherited --- Genetic diseases --- Hereditary diseases --- Inherited diseases --- Diseases --- Medical genetics
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Nervous System Diseases --- genetics --- Nervous System Diseases - genetics --- Neurosciences --- Nervous system diseases --- Neurodegenerative diseases --- Genetic predisposition to disease --- Hereditary diseases --- Genetics, Medical --- Genetic techniques
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The studies on genetic disorders have been rapidly advancing in recent years as to be able to understand the reasons why genetic disorders are caused. The first Section of this volume provides readers with background and several methodologies for understanding genetic disorders. Genetic defects, diagnoses and treatments of the respective unifactorial and multifactorial genetic disorders are reviewed in the second and third Sections. Certainly, it is quite difficult or almost impossible to cure a genetic disorder fundamentally at the present time. However, our knowledge of genetic functions has rapidly accumulated since the double-stranded structure of DNA was discovered by Watson and Crick in 1956. Therefore, nowadays it is possible to understand the reasons why genetic disorders are caused. It is probable that the knowledge of genetic disorders described in this book will lead to the discovery of an epoch of new medical treatment and relieve human beings from the genetic disorders of the future.
Medical genetics. --- Genetic disorders. --- Congenital diseases --- Disorders, Genetic --- Disorders, Inherited --- Genetic diseases --- Hereditary diseases --- Inherited diseases --- Diseases --- Medical genetics --- Clinical genetics --- Heredity of disease --- Human genetics --- Medical sciences --- Pathology --- Genetic disorders --- Genetic aspects
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In the 1980's, a research team led by Parisian scientists identified several unique DNA sequences, or haplotypes, linked to sickle cell anemia in African populations. After casual observations of how patients managed this painful blood disorder, the researchers in question postulated that the Senegalese type was less severe. The Enculturated Gene traces how this genetic discourse has blotted from view the roles that Senegalese patients and doctors have played in making sickle cell ""mild"" in a social setting where public health priorities and economic austerity programs have forced people to
Kinship --- Genetic disorders --- Sickle cell anemia --- Ethnology --- Clans --- Consanguinity --- Families --- Kin recognition --- Congenital diseases --- Disorders, Genetic --- Disorders, Inherited --- Genetic diseases --- Hereditary diseases --- Inherited diseases --- Diseases --- Medical genetics --- Drepanocytic anemia --- Meniscocytosis --- Sickle cell disease --- Blood hyperviscosity syndrome --- Hemoglobinopathy --- Hemolytic anemia --- Health aspects --- Social aspects --- Patients --- Services for --- Genetic aspects. --- Africa. --- African anthropology. --- African genetics. --- African sicklers. --- Albert Royer Children's Hospital. --- CNTS. --- Centre nationale de transfusion sanguine. --- DNA haplotypes. --- DNA sequences. --- HbAS. --- International Organization for the Fight against Sickle Cell. --- National Blood Transfusion Center. --- OILD. --- RFLP. --- Restriction Fragment Length Polymorphism. --- Senegal. --- Senegalese attitudes. --- Senegalese sickle cell. --- alternative care. --- biological expressions. --- biosocial politics. --- culture. --- disease experiences. --- disease expression. --- economic austerity. --- economically triaged care. --- ethnic population purity. --- fagara. --- genetic difference. --- genetic sequence. --- geneticists. --- global health problems. --- global health. --- healing practices. --- health intervention. --- health. --- healthy sicklers. --- heterozygous sickle cell. --- low-tech strategy. --- multilateral institutions. --- normalization techniques. --- patient advocacy. --- political apathy. --- population. --- public health. --- public neglect. --- self-care. --- sickle cell DNA markers. --- sickle cell anemia. --- sickle cell gene. --- sickle cell research. --- sickle cell trait. --- sicklers. --- social networks. --- traditional plants. --- vitality.
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