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Autoimmune Diseases: Acute and Complex Situations provides a detailed overview of conditions associated with autoimmune diseases that are considered either life-threatening or requiring complex management. These include abdominal pain, arthritis, cutaneous ulcers, gastrointestinal hemorrhage, epilepsy, pancreatitis, stroke and white-matter CNS lesions. Autoimmune Diseases: Acute and Complex Situations addresses the latest clinical and immunological prognostic factors that may help to identify patients at higher risk of developing potentially life-threatening involvement. This book comprehensively helps the reader to diagnose these patients, in whom an early therapeutic approach is essential. Autoimmune Diseases: Acute and Complex Situations is a valuable reference tool for rheumatologists, internists, immunologists, and all the specialists involved in the multidisciplinary care of patient with rheumatic and systemic autoimmune diseases.

Autoimmune diseases -- Juvenile literature. --- Autoimmune diseases. --- Immunologic diseases. --- Autoimmune diseases --- Comorbidity --- Critical care medicine --- Epidemiologic Factors --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Immune System Diseases --- Patient Care --- Quality of Health Care --- Therapeutics --- Public Health --- Health Services --- Diseases --- Health Care Facilities, Manpower, and Services --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Health Care --- Autoimmune Diseases --- Early Diagnosis --- Critical Care --- Diagnosis --- Medicine --- Health & Biological Sciences --- Clinical Immunology --- Musculoskeletal System Diseases --- Complications --- Early detection --- Autoimmunologic diseases --- Medicine. --- Internal medicine. --- Rheumatology. --- Medicine & Public Health. --- Internal Medicine. --- Autoimmunity --- Immunologic diseases --- Medicine, Internal --- Internal medicine --- Connective tissues --- Joints

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Sex matters!  Are there differences between the sexes when it comes to brain function and the behaviours that result? This volume attempts to answer this fundamental question. If the answer is ‘yes’ then this should impact upon our approach to treating mental illness in humans, and to modelling it in animals, as we look for aetiological and pharmacological solutions. This volume covers two main aspects of research into sex differences in psychopharmacology: preclinical research, and clinical work in this area. The first part of the volume deals with the preclinical research, and explains how male and female animals differ in their sexual behaviour, drug dependence, cognition, genetics and stress reactivity, with an introductory chapter explaining basic mechanisms of sex steroid action in the body and brain. The second part focuses on the importance of improved understanding of sex differences in our approach to the treatment of psychiatric illness. This includes illnesses such as autism, anorexia, depression, schizophrenia, and bipolar disorder. This volume will be of considerable interest to mental health professionals, including psychiatrists , nurses , allied health clinicians and pharmacists. It will also be helpful and important for preclinical researchers working in neuroscience, psychopharmacology and reproductive endocrinology.      .

Developmental neurobiology. --- Neurons -- physiology. --- Psychopharmacology. --- Psychophysiology. --- Mental illness --- Psychiatry and Psychology --- Central Nervous System --- Epidemiologic Factors --- Gonadal Hormones --- Therapeutics --- Nervous System --- Quality of Health Care --- Hormones --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Public Health --- Hormones, Hormone Substitutes, and Hormone Antagonists --- Environment and Public Health --- Health Care Quality, Access, and Evaluation --- Anatomy --- Health Care --- Chemicals and Drugs --- Sex Factors --- Brain --- Mental Disorders --- Drug Therapy --- Gonadal Steroid Hormones --- Medicine --- Psychiatry --- Health & Biological Sciences --- Psychiatry - General --- Neurology --- Physiological aspects --- Psychopharmacology --- Reproductive health. --- Sex differences. --- Human reproduction --- Human reproductive health --- Human reproductive medicine --- Reproductive medicine --- Behavioral pharmacology --- Drugs --- Health aspects --- Psychotropic effects --- Medicine. --- Pharmacy. --- Neurosciences. --- Endocrinology. --- Psychiatry. --- Reproductive medicine. --- Biomedicine. --- Reproductive Medicine. --- Health --- Chemotherapy --- Pharmacology --- Psychotropic drugs --- Chemistry --- Materia medica --- Internal medicine --- Medicine and psychology --- Mental health --- Psychology, Pathological --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Endocrinology .

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That precursors of adult coronary artery disease, hypertension, and type II diabetes begin in childhood have been clearly established by the Bogalusa Heart Study. This unique research program has been able to follow a biracial (black/white) population over 35 years from childhood through mid-adulthood to provide perspectives on the natural history of adult heart diseases. Not only do these observations describe trajectories of cardio-metabolic risk variables leading to these diseases but provide a rationale for the need to begin prevention beginning in childhood. The trajectories of the burden of cardio-metabolic risk variables in the context of their fetal origin and chromosome telomere dynamics provide some insight into the metabolic imprinting in utero and aging process. The observed racial contrasts on cardio-metabolic risk variables implicate various biologic pathways interacting with environment contributing to the high morbidity and mortality from related diseases in our population. To address the seriousness of the onset of cardiovascular disease in youth, approaches to primordial prevention are described focussing on childhood health education as an important aspect of Preventive Cardiology.

Coronary artery -- Stenosis -- Relapse. --- Coronary artery bypass -- Decision-making. --- Coronary artery bypass. --- Coronary artery. --- Coronary heart disease. --- Coronary heart disease --- Hypertension in children --- Non-insulin-dependent diabetes --- Health surveys --- Vascular Diseases --- Causality --- Risk --- Preventive Health Services --- Diabetes Mellitus --- Myocardial Ischemia --- Health Care Facilities, Manpower, and Services --- Epidemiologic Factors --- Health Care --- Glucose Metabolism Disorders --- Probability --- Heart Diseases --- Health Services --- Endocrine System Diseases --- Cardiovascular Diseases --- Statistics as Topic --- Metabolic Diseases --- Diseases --- Quality of Health Care --- Public Health --- Environment and Public Health --- Epidemiologic Methods --- Health Care Evaluation Mechanisms --- Health Care Quality, Access, and Evaluation --- Nutritional and Metabolic Diseases --- Investigative Techniques --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Health Promotion --- Risk Factors --- Coronary Disease --- Diabetes Mellitus, Type 2 --- Hypertension --- Medicine --- Health & Biological Sciences --- Public Health - General --- Prevention --- Risk factors --- Cardiovascular system --- Metabolic syndrome. --- Risk factors. --- Circulatory system --- Vascular system --- Cardiovascular syndrome, Metabolic --- Dysmetabolic syndrome X --- Insulin resistance syndrome --- Metabolic cardiovascular syndrome --- Metabolic syndrome X --- Medicine. --- Human physiology. --- Public health. --- Health promotion. --- Geriatrics. --- Biomedicine. --- Biomedicine general. --- Medicine/Public Health, general. --- Human Physiology. --- Geriatrics/Gerontology. --- Public Health. --- Health Promotion and Disease Prevention. --- Blood --- Insulin resistance --- Metabolism --- Syndromes --- Circulation --- Disorders --- Gerontology --- Older people --- Human biology --- Medical sciences --- Physiology --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Health and hygiene --- Health Workforce --- Biomedicine, general. --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation

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The scenario is all too common, patients presenting with medical conditions who have co-occurring psychological disorders, and vice versa. Clinical challenges include poor treatment outcome, low adherence, and impaired quality of life. Yet as a common clinical phenomenon, these co-morbidities tend to be understudied by researchers and undertreated by practitioners. Psychological Co-Morbidities of Physical Illness is the first comprehensive reference addressing the topic from a behavioral medicine perspective and focusing on evidence-based practice. This accessible volume explains the physiological and behavioral mechanisms underlying co-morbid physical and psychological disorders, addresses treatment approaches and challenges with this population, and synthesizes findings across the disciplines. Each chapter focuses on a chronic medical condition and the most prevalent co-morbid psychological disorders for each, such as depression, anxiety, and psychotic disorders. For each condition, contributors review the treatment outcome literature and provide detailed information about effective psychological and pharmacological interventions, assessment instruments, treatment considerations (e.g., sequencing, contraindications), and, where relevant, cultural issues. Among the medical conditions covered:Obesity Type 2 diabetes Cardiovascular disease Tobacco dependence Chronic pain CancerDementia Chronic obstructive pulmonary disease Irritable bowel syndrome Multiple sclerosis Psychological Co-Morbidities of Physical Illness is an invaluable decision-making resource for practitioners and trainees working with co-morbid patients in clinical, public health, and academic settings, including psychologists and other mental health professionals, primary care and specialist physicians, nurses, and allied health care providers. Researchers and epidemiologists will find it a highly useful source of current data as well as a springboard for future research.

Behavior therapy. --- Comorbidity. --- Dual diagnosis -- Patients -- Rehabilitation. --- Dual diagnosis -- Treatment. --- Comorbidity --- Behavior therapy --- Dual diagnosis --- Evidence-Based Practice --- Medicine --- Epidemiologic Factors --- Behavioral Sciences --- Pathologic Processes --- Clinical Medicine --- Psychiatry and Psychology --- Behavioral Disciplines and Activities --- Quality of Health Care --- Public Health --- Health Occupations --- Pathological Conditions, Signs and Symptoms --- Health Care Quality, Access, and Evaluation --- Disciplines and Occupations --- Diseases --- Environment and Public Health --- Health Care --- Mental Disorders --- Evidence-Based Medicine --- Behavioral Medicine --- Disease --- Psychiatry --- Health & Biological Sciences --- Public Health - General --- Substance Abuse Disorders --- Psychotherapy --- Treatment --- Rehabilitation --- Patients --- Dual diagnosis. --- Coexisting disease --- Coexisting illness --- Alcoholism and mental illness --- Dual disorders --- Mental illness and alcoholism --- Mental illness and substance abuse --- Behavioral therapy --- Medicine. --- Public health. --- Clinical psychology. --- Health psychology. --- Medicine & Public Health. --- Public Health. --- Health Psychology. --- Clinical Psychology. --- Epidemiology --- Mental illness --- Substance abuse --- Behavior modification --- Psychology, clinical. --- Psychology, Applied --- Psychological tests --- Health psychology --- Health psychology, Clinical --- Psychology, Clinical health --- Psychology, Health --- Salutogenesis --- Clinical psychology --- Medicine and psychology --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation