Abstract | Keywords | Export | Availability | Bookmark

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

We have entered the era of molecular immunohematology in which DNA is analyzed to predict red blood cell and platelet phenotypes. Indeed, many laboratories and blood banks across the world have already adopted and implemented molecular techniques. Some fear that serology is now becoming outdated, but immunohematology techniques often supplement the work of serologists, and several leading serology laboratories are the very same ones that were early adopters of molecular immunohematology. This book is a thorough review of molecular immunohematology and is aimed at anyone interested in how it is changing blood bank and transfusion medicine. BeadChip Molecular Immunohematology opens with a history of serology before it provides an overview of gene expression, how genetic variations translate into antigenic differences on the surfaces of cells, and techniques that have been developed to detect genetic variations. It then describes in detail the BeadChip technology developed by BioArray Solutions, the molecular immunohematology system that has been most widely adopted in blood blank laboratories. The remainder of the book focuses on analyses and case studies from around the world to describe how molecular immunohematology is being used in various settings for various purposes. It includes a discussion of the significant advances that have been made to incorporate Rh testing on the BeadChip platform as well as the potential use of that system.

Blood banks -- Congresses. --- Blood banks. --- Blood Group Antigens. --- Blood Grouping and Crossmatching. --- Blood Transfusion -- methods. --- Gene Expression Profiling. --- Hematologic Diseases -- immunology. --- Immunohematology. --- Blood --- Immunology --- Medical laboratories --- Medicine --- Monoclonal antibodies --- Nucleic Acid Hybridization --- Molecular Probe Techniques --- Genetic Techniques --- Isoantigens --- Investigative Techniques --- Microarray Analysis --- Sequence Analysis --- Biological Specimen Banks --- Antigens, Surface --- Histocompatibility Testing --- Hematologic Tests --- Immunologic Tests --- Antigens --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Microchip Analytical Procedures --- Laboratory Techniques and Procedures --- Health Facilities --- Blood Grouping and Crossmatching --- Oligonucleotide Array Sequence Analysis --- Methods --- Blood Group Antigens --- Gene Expression Profiling --- Blood Banks --- Biological Factors --- Health Care Facilities, Manpower, and Services --- Immunologic Techniques --- Chemistry Techniques, Analytical --- Diagnosis --- Chemicals and Drugs --- Health Care --- Health & Biological Sciences --- Hematologic Diseases --- Transfusion --- Immunology. --- Medical laboratories. --- Medicine. --- Monoclonal antibodies. --- Antibodies, Monoclonal --- Monoclonal immunoglobulins --- Clinical sciences --- Medical profession --- Immunobiology --- Blood transfusion --- Blood transfusion therapy --- Hemotherapy --- Transfusion medicine --- Transfusion of blood --- Transfusion therapy --- Transfusion therapy, Blood --- Transfusion. --- Antibodies. --- Laboratory medicine. --- Molecular biology. --- Blood transfusion. --- Biomedicine. --- Biomedicine general. --- Laboratory Medicine. --- Molecular Medicine. --- Blood Transfusion Medicine. --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Serology --- Immunoglobulins --- Molecular cloning --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Surgery --- Blood banks --- Blood groups --- Hospitals --- Transfusion-free surgery --- Transfusion committees --- Biomedicine, general. --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis --- Antibodies --- Immune globulins --- Immune serum globulin --- Blood proteins --- Globulins --- Plasma cells --- Antibody diversity --- Bacterial immunoglobulin-binding proteins