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Myelodysplasic Syndromes --- Bone Marrow Diseases --- Adult --- Myelodysplastic Syndromes. --- Bone Marrow Diseases. --- Syndrome myélodysplasique --- Moelle osseuse --- Maladies --- Syndrome myélodysplasique. --- Maladies. --- Maladies de la moelle osseuse.
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Blood -- Diseases. --- Bone marrow -- Diseases. --- Pathology. --- Hemic and Lymphatic Diseases --- Immune System --- Diseases --- Hemic and Immune Systems --- Anatomy --- Hematologic Diseases --- Bone Marrow --- Blood --- Bone marrow --- Diseases. --- Disease (Pathology) --- Medical sciences --- Medicine --- Medicine, Preventive --- Clinical hematology --- Hematologic diseases --- Hematology
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Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias. MDS was previously named as “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia. According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged 70 or older. It is believed that the true incidence of MDS have been underestimated however it seems to be comparable to that for multiple myeloma and chronic lymphocytic leukemia. In the past decade much progress had been made; we know more on the disease pathology, there is more emphasis on the care and more targeted therapy had been invested. Authors provide updated knowledge in this book on all clinically important aspects of the disease. Hot topics of our days are discussed in chapters by outstanding and well known scientists from all over the world. We would offer this product both for medical students and postgraduates as well as for all who are interested in this very exciting and fast progressing field of hematology. With this work authors should call attention on the disease for decision makers in health care systems as well. .
Bone marrow -- Transplantation. --- Bone marrow. --- Myelodysplastic syndromes. --- Myelodysplastic syndromes --- Bone Marrow Diseases --- Hematologic Diseases --- Hemic and Lymphatic Diseases --- Diseases --- Myelodysplastic Syndromes --- Medicine --- Health & Biological Sciences --- Bone marrow --- Dysmyelopoietic syndromes --- Dysplasia --- Medicine. --- Hematology. --- Biomedicine. --- Biomedicine general. --- Medicine/Public Health, general. --- Syndromes --- Preleukemia --- Haematology --- Internal medicine --- Blood --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Biomedicine, general.
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This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.
Blood -- Diseases. --- Leukemia. --- Myeloproliferative disorders -- Pathophysiology. --- Myeloproliferative disorders -- Treatment. --- Myeloproliferative disorders. --- Myeloproliferative disorders --- Bone marrow --- Hematologic Neoplasms --- Bone Marrow Diseases --- Hematologic Diseases --- Neoplasms by Site --- Myelodysplastic-Myeloproliferative Diseases --- Bone Marrow Neoplasms --- Hemic and Lymphatic Diseases --- Neoplasms --- Diseases --- Medicine --- Health & Biological Sciences --- Pathology --- Tumors --- Myeloproliferative syndromes --- Tumors. --- Molecular aspects. --- Treatment. --- Tumours --- Myeloproliferative syndrome --- Medicine. --- Angiology. --- Hematology. --- Oncology. --- Medical biochemistry. --- Medicine & Public Health. --- Medical Biochemistry. --- Cysts (Pathology) --- Oncology --- Oncology . --- Angiography. --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Blood-vessels --- Diagnosis, Radioscopic --- Radiography, Medical --- Haematology --- Internal medicine --- Blood --- Composition --- Radiography --- Medical biochemistry --- Pathobiochemistry --- Pathological biochemistry --- Biochemistry
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