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2011 (4)

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Book
Les syndromes myélodysplasiques de l'adulte
Authors: --- ---
ISSN: 12951404 ISBN: 9782742007950 2742007954 Year: 2011 Publisher: Montrouge : J. Libbey Eurotext,


Book
Blood and bone marrow pathology
Authors: --- ---
ISBN: 0702045357 070203147X 1336255072 9780702031472 Year: 2011 Publisher: London : Churchill Livingstone,


Book
The myelodysplastic syndromes
Author:
ISBN: 940178390X 9400704399 9786613081322 9400704402 1283081326 Year: 2011 Publisher: Dordrecht : Springer,

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Abstract

Myelodysplastic syndromes (MDS) are the most common hematological malignancies involving mostly the elderly population. The major morbidity relates to patients’ symptomatic cytopenias. MDS was previously named as  “preleukemia “ or “ smoldering leukemia” as the lack of terminal cells in MDS and because about 25% of all cases progresses into acute myeloid leukemia. According to various reports the annual incidence of MDS ranges widely from 2-12 per 100.000, increasing to 30-50 cases per 100.000 among persons aged  70  or older. It is believed that the true incidence of MDS have been underestimated however it seems to be comparable to that for multiple myeloma and chronic lymphocytic leukemia.   In the past decade much progress had been made; we know more on the disease pathology, there is more emphasis on the care and more targeted therapy had been invested. Authors provide updated knowledge in this book on all clinically important aspects of the disease. Hot topics of our days are discussed in chapters by outstanding and well known scientists from all over the world. We would offer this product both for medical students and postgraduates as well as for all who are interested in this very exciting and fast progressing field of hematology. With this work authors should call attention on the disease for decision makers in health care systems as well.  .


Book
Myeloproliferative neoplasms : biology and therapy
Authors: ---
ISBN: 1607612658 9786612972140 1282972146 1607612666 1617797111 Year: 2011 Publisher: New York : Humana Press,

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Abstract

This succinct resource provides an ideal balance of the biology and practical therapeutic strategies for classic and non-classic BCR-ABL-negative myeloproliferative neoplasms. Utilizing current World Health Organization nomenclature, classification, and diagnostic criteria, international experts have assembled to convey the most up-to-date knowledge in this rapidly evolving field. The opening chapters cover the diagnosis and classification, genetics, cytogenetic findings, and prognostic factors of MPNs. Further chapters explore therapies specific to the different disease entities, including polycythemia vera, essential thrombocytopenia, myelofibrosis, and eosinophilic disorders, and mastocytosis. Unique areas of discussion include JAK2 inhibitor therapy, hematopoietic stem cell transplantation, and blastic transformation. A valuable reference for practicing hematologists, this forefront book enriches our understanding of recent discoveries and their impact on conventional and investigational treatments.

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