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The information presented in the Handbook of Brain Microcircuits was previously dispersed across the literature. In fact, some microcircuits were previously brought together for selected regions in The Synaptic Organization of the Brain edited by Gordon Shepherd (2003) and Microcircuits edited by Sten Grillner and Ann Graybiel (2006). This handbook greatly extends that coverage to over 40 regions of the vertebrate and invertebrate nervous system becoming the go-to source for key circuits within the neurosciences. In order to focus on principles, each chapter is brief, organized around 1-3 wiri
Brain. --- Neural circuitry. --- Neurophysiology. --- Brain --- Neurons --- Nerve Net. --- Synaptic Transmission. --- physiology.
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"Computational neuroscience is the theoretical study of the brain to uncover the principles and mechanisms that guide the development, organization, information processing, and mental functions of the nervous system. Although not a new area, it is only recently that enough knowledge has been gathered to establish computational neuroscience as a scientific discipline in its own right. Given the complexity of the field, and its increasing importance in progressing our understanding of how the brain works, there has long been a need for an introductory text on what is often assumed to be an impenetrable topic. The new edition of Fundamentals of Computational Neuroscience build on the success and strengths of the first edition. It introduces the theoretical foundations of neuroscience with a focus on the nature of information processing in the brain. The book covers the introduction and motivation of simplified models of neurons that are suitable for exploring information processing in large brain-like networks. Additionally, it introduces several fundamental network architectures and discusses their relevance for information processing in the brain, giving some examples of models of higher-order cognitive functions to demonstrate the advanced insight that can be gained with such studies. Each chapter starts by introducing its topic with experimental facts and conceptual questions related to the study of brain function. An additional feature is the inclusion of simple Matlab programs that can be used to explore many of the mechanisms explained in the book. An accompanying webpage includes programs for download. The book is aimed at those within the brain and cognitive sciences, from graduate level and upwards"--Provided by publisher.
Computational neuroscience. --- Computational neurosciences --- Computational biology --- Neurosciences --- Neurosciences informatiques --- Brain --- Computational Biology --- Models, Neurological. --- Nerve Net. --- Neurons --- Physiology. --- Methods.
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Virtually all scientific problems in neuroscience require mathematical analysis, and all neuroscientists are increasingly required to have a significant understanding of mathematical methods. There is currently no comprehensive, integrated introductory book on the use of mathematics in neuroscience; existing books either concentrate solely on theoretical modeling or discuss mathematical concepts for the treatment of very specific problems. This book fills this need by systematically introducing mathematical and computational tools in precisely the contexts that first established their important
Computational biology -- Methods. --- Models, Neurological. --- Nerve net. --- Neurons -- Physiology. --- Electrophysiological Processes --- Signal Transduction --- Models, Biological --- Nervous System Physiological Processes --- Cells --- Biological Science Disciplines --- Phenomena and Processes --- Nervous System --- Biology --- Nervous System Physiological Phenomena --- Cell Physiological Processes --- Models, Theoretical --- Electrophysiological Phenomena --- Anatomy --- Natural Science Disciplines --- Biochemical Processes --- Physiological Processes --- Nerve Net --- Synaptic Transmission --- Mathematical Concepts --- Neurosciences --- Computational Biology --- Neurons --- Models, Neurological --- Investigative Techniques --- Cell Physiological Phenomena --- Musculoskeletal and Neural Physiological Phenomena --- Biochemical Phenomena --- Physiological Phenomena --- Chemical Processes --- Disciplines and Occupations --- Chemical Phenomena --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Neurosciences. --- Mathematics. --- Medical mathematics --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Health Workforce
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In this engaging, even lyrical, book, Jan Lauwereyns examines the neural underpinnings of decision-making, using 'bias' as his core concept rather than the more common but noncommittal terms 'selection' and 'attention'.
Mathematical statistics --- Physiology of nerves and sense organs --- Neural circuitry --- Decision making --- Bayesian statistical decision theory. --- Neural networks (Neurobiology) --- Nerve Net --- Judgment --- Models, Theoretical. --- Mathematical models. --- Physiological aspects. --- physiology. --- Bayesian statistical decision theory --- Physiology --- Models, Theoretical --- Thinking --- Nervous System --- Investigative Techniques --- Biological Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Natural Science Disciplines --- Mental Processes --- Anatomy --- Disciplines and Occupations --- Psychological Phenomena and Processes --- Psychiatry and Psychology --- Neuroscience --- Human Anatomy & Physiology --- Health & Biological Sciences --- Mathematical models --- Physiological aspects --- Biological neural networks --- Nets, Neural (Neurobiology) --- Networks, Neural (Neurobiology) --- Neural nets (Neurobiology) --- Bayes' solution --- Bayesian analysis --- Deciding --- Decision (Psychology) --- Decision analysis --- Decision processes --- Making decisions --- Management --- Management decisions --- Circuitry, Neural --- Circuits, Neural --- Nerve net --- Nerve network --- Neural circuits --- Neurocircuitry --- Neuronal circuitry --- Cognitive neuroscience --- Neurobiology --- Statistical decision --- Choice (Psychology) --- Problem solving --- Electrophysiology --- Nervous system --- Reflexes --- NEUROSCIENCE/General --- COGNITIVE SCIENCES/General --- Physiology.
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Neuroscience has long been focused on understanding neural plasticity in both development and adulthood. However, experimental work in this area has focused almost entirely on plasticity at excitatory synapses. A growing body of evidence suggests that plasticity at inhibitory GABAergic and glycinergic synapses is of critical importance during both development and aging. Only a few investigators have been engaged in research on how inhibitory circuits are formed during development or how they are involved in plasticity of developing sensory and motor circuitry. Developmental Plasticity of Inhibitory Circuitry approaches the subject of inhibitory plasticity from several levels of analysis, from synapses to circuits to systems to clinical, summarizing several possible mechanisms and collecting some of the most fascinating work in this under-studied area. It is meant to provide an overview for basic and clinical researchers and students interested in neural plasticity and to stimulate further research. About the Editor: Dr. Sarah L. Pallas is a Professor of Neuroscience and Biology at Georgia State University. She earned her Ph.D. in Neurobiology and Behavior at Cornell University, under the tutelage of Dr. Barbara Finlay. Her postdoctoral training was received at M.I.T. in the laboratory of Dr. Mriganka Sur. Her research concerns developmental neurobiology and sensory physiology, and in particular the role of sensory experience in the development and plasticity of neural circuits.
Cognitive neuroscience. --- Developmental neurobiology. --- Posner, Michael I. --- Neural circuitry --- Neuroplasticity --- Developmental neurobiology --- Biological Science Disciplines --- Physiological Processes --- Cells --- Nervous System Physiological Processes --- Anatomy --- Growth and Development --- Nervous System --- Neurons --- Neuronal Plasticity --- Physiology --- Physiological Phenomena --- Natural Science Disciplines --- Nervous System Physiological Phenomena --- Phenomena and Processes --- Disciplines and Occupations --- Musculoskeletal and Neural Physiological Phenomena --- Medicine --- Human Anatomy & Physiology --- Neuroscience --- Neurology --- Health & Biological Sciences --- Neural circuitry. --- Adaptation. --- Adaptation of neural circuitry --- Circuitry, Neural --- Circuits, Neural --- Nerve net --- Nerve network --- Neural circuits --- Neurocircuitry --- Neuronal circuitry --- Medicine. --- Neurosciences. --- Neurology. --- Rehabilitation medicine. --- Developmental biology. --- Neurobiology. --- Biomedicine. --- Developmental Biology. --- Rehabilitation Medicine. --- Adaptation (Physiology) --- Electrophysiology --- Nervous system --- Neural networks (Neurobiology) --- Reflexes --- Rehabilitation. --- Neurosciences --- Development (Biology) --- Biology --- Growth --- Ontogeny --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Medical sciences --- Diseases --- Neurology . --- Medicine, Rehabilitation --- Rehabilitation medicine --- Rehabilitation --- Medicine, Physical
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The hippocampus plays an indispensable role in the formation of new memories in the mammalian brain. It is the focus of intense research and our understanding of its physiology, anatomy, and molecular structure has rapidly expanded in recent years. Yet, still much needs to be done to decipher how hippocampal microcircuits are built and function. Here, we present an overview of our current knowledge and a snapshot of ongoing research into these microcircuits. Rich in detail, Hippocampal Microcircuits: A Computational Modeler’s Resource Book provides focused and easily accessible reviews on various aspects of the theme. It is an unparalleled resource of information, including both data and techniques that will be an invaluable companion to all those wishing to develop computational models of hippocampal neurons and neuronal networks. The book is divided into two main parts. In the first part, leading experimental neuroscientists discuss data on the electrophysiological, neuroanatomical, and molecular characteristics of hippocampal circuits. The various types of excitatory and inhibitory neurons are reviewed along with their connectivity and synaptic properties. Single cell and ensemble activity patterns are presented from in vitro models, as well as anesthetized and freely moving animals. In the second part, computational neuroscientists describe models of hippocampal microcircuits at various levels of complexity, from single neurons to large-scale networks. Additionally, a chapter is devoted to simulation environments currently used by computational neuroscientists in developing their models. In addition to providing concise reviews and a wealth of data, the chapters also identify central questions and unexplored areas that will define future research in computational neuroscience. About the Editors: Dr. Vassilis Cutsuridis is a Research Fellow in the Department of Computing Science and Mathematics at the University of Stirling, Scotland, UK. Dr. Bruce P. Graham is a Reader in Computing Science in the Department of Computing Science and Mathematics at the University of Stirling. Dr. Stuart Cobb and Dr. Imre Vida are Senior Lecturers in the Neuroscience and Molecular Pharmacology Department at the University of Glasgow, Scotland, UK.
Hippocampus (Brain) -- Computer simulation. --- Neural networks (Neurobiology) -- Computer simulation. --- Hippocampus (Brain) --- Neural networks (Neurobiology) --- Nervous System --- Electrophysiological Processes --- Signal Transduction --- Computing Methodologies --- Limbic System --- Biological Science Disciplines --- Cerebral Cortex --- Models, Biological --- Nervous System Physiological Processes --- Synaptic Transmission --- Physiology --- Computer Simulation --- Nerve Net --- Models, Neurological --- Hippocampus --- Neural Pathways --- Biochemical Processes --- Nervous System Physiological Phenomena --- Cerebrum --- Electrophysiological Phenomena --- Physiological Processes --- Anatomy --- Models, Theoretical --- Cell Physiological Processes --- Brain --- Information Science --- Natural Science Disciplines --- Chemical Processes --- Physiological Phenomena --- Disciplines and Occupations --- Biochemical Phenomena --- Central Nervous System --- Cell Physiological Phenomena --- Investigative Techniques --- Telencephalon --- Musculoskeletal and Neural Physiological Phenomena --- Chemical Phenomena --- Phenomena and Processes --- Prosencephalon --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Human Anatomy & Physiology --- Medicine --- Neurology --- Neuroscience --- Health & Biological Sciences --- Computer simulation --- Computer simulation. --- Biological neural networks --- Nets, Neural (Neurobiology) --- Networks, Neural (Neurobiology) --- Neural nets (Neurobiology) --- Ammon's horn --- Cornu ammonis --- Medicine. --- Neurosciences. --- Bioinformatics. --- Computational biology. --- Neurobiology. --- Biomedicine. --- Computer Appl. in Life Sciences. --- Neurosciences --- Biology --- Bioinformatics --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology --- Neural sciences --- Neurological sciences --- Medical sciences --- Nervous system --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Pathology --- Physicians --- Data processing --- Cognitive neuroscience --- Neurobiology --- Neural circuitry --- Cerebral cortex --- Limbic system --- Data processing. --- Bioinformatics . --- Computational biology .
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Artificial neural networks are used to model systems that receive inputs and produce outputs. The relationships between the inputs and outputs and the representation parameters are critical issues in the design of related engineering systems, and sensitivity analysis concerns methods for analyzing these relationships. Perturbations of neural networks are caused by machine imprecision, and they can be simulated by embedding disturbances in the original inputs or connection weights, allowing us to study the characteristics of a function under small perturbations of its parameters. This is the first book to present a systematic description of sensitivity analysis methods for artificial neural networks. It covers sensitivity analysis of multilayer perceptron neural networks and radial basis function neural networks, two widely used models in the machine learning field. The authors examine the applications of such analysis in tasks such as feature selection, sample reduction, and network optimization. The book will be useful for engineers applying neural network sensitivity analysis to solve practical problems, and for researchers interested in foundational problems in neural networks.
Neural networks (Computer science). --- Sensitivity theory (Mathematics). --- Neural networks (Computer science) --- Sensitivity theory (Mathematics) --- Mechanical Engineering --- Engineering & Applied Sciences --- Computer Science --- Mechanical Engineering - General --- Information Technology --- Artificial Intelligence --- Neural circuitry. --- Circuitry, Neural --- Circuits, Neural --- Nerve net --- Nerve network --- Neural circuits --- Neurocircuitry --- Neuronal circuitry --- Artificial neural networks --- Nets, Neural (Computer science) --- Networks, Neural (Computer science) --- Neural nets (Computer science) --- Computer science. --- Artificial intelligence. --- Computer simulation. --- Pattern recognition. --- Statistical physics. --- Dynamical systems. --- Engineering design. --- Control engineering. --- Robotics. --- Mechatronics. --- Computer Science. --- Artificial Intelligence (incl. Robotics). --- Control, Robotics, Mechatronics. --- Statistical Physics, Dynamical Systems and Complexity. --- Pattern Recognition. --- Simulation and Modeling. --- Engineering Design. --- Mechanical engineering --- Microelectronics --- Microelectromechanical systems --- Automation --- Machine theory --- Control engineering --- Control equipment --- Control theory --- Engineering instruments --- Programmable controllers --- Design, Engineering --- Engineering --- Industrial design --- Strains and stresses --- Dynamical systems --- Kinetics --- Mathematics --- Mechanics, Analytic --- Force and energy --- Mechanics --- Physics --- Statics --- Mathematical statistics --- Design perception --- Pattern recognition --- Form perception --- Perception --- Figure-ground perception --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- AI (Artificial intelligence) --- Artificial thinking --- Electronic brains --- Intellectronics --- Intelligence, Artificial --- Intelligent machines --- Machine intelligence --- Thinking, Artificial --- Bionics --- Cognitive science --- Digital computer simulation --- Electronic data processing --- Logic machines --- Self-organizing systems --- Fifth generation computers --- Neural computers --- Informatics --- Science --- Design --- Statistical methods --- Electrophysiology --- Nervous system --- Neural networks (Neurobiology) --- Reflexes --- Artificial intelligence --- Natural computation --- Soft computing --- Optical pattern recognition. --- Artificial Intelligence. --- Complex Systems. --- Optical data processing --- Pattern perception --- Perceptrons --- Visual discrimination --- Automation. --- System theory. --- Pattern recognition systems. --- Control, Robotics, Automation. --- Automated Pattern Recognition. --- Computer Modelling. --- Pattern classification systems --- Pattern recognition computers --- Computer vision --- Systems, Theory of --- Systems science --- Automatic factories --- Automatic production --- Computer control --- Engineering cybernetics --- Factories --- Industrial engineering --- Mechanization --- Assembly-line methods --- Automatic control --- Automatic machinery --- CAD/CAM systems --- Robotics --- Philosophy
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