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Acute myelogenous leukemia (AML), is the most common form of leukemia in adults. AML is a deadly form of malignancy, the prognosis for which has not improved in the last two decades. More importantly, it is a malignancy that is seen in older adults, therefore the number of cases is likely to rise as the population ages. Over the past 15 years, genetic mechanisms underlying AML have begun to unfold. Additional research in this area has helped identify key components and characteristics. Consequently, targeted therapy of AML is receiving much attention. It is the hope of researchers that as with chronic myelogenous leukemia (CML), and the drug, Gleevec, a targeted therapy for AML will be discovered. "The effective treatment of acute myelogenous leukemia remains a great challenge. This text reviews our understanding of the molecular and biologic basis of the disease. Leading investigators address advances in prognostication and therapeutic strategies that have significant promise." Steven T. Rosen, M.D. Series Editor.
Acute myeloid leukemia -- Genetic aspects. --- Acute myeloid leukemia. --- Leukemia, Myeloid, Acute -- genetics. --- MEDICAL -- Oncology. --- Acute myeloid leukemia --- Leukemia, Myeloid --- Biology --- Genetics --- Leukemia, Myeloid, Acute --- Biological Science Disciplines --- Leukemia --- Natural Science Disciplines --- Neoplasms by Histologic Type --- Neoplasms --- Disciplines and Occupations --- Diseases --- Medicine --- Hematologic Diseases --- Oncology --- Health & Biological Sciences --- Genetic aspects. --- Gene therapy. --- Acute myelogenous leukemia --- Acute myeloid granulocytic leukemia --- Acute myelocytic leukemia --- AML (Disease) --- Medicine. --- Hematology. --- Oncology. --- System theory. --- Medicine & Public Health. --- Systems Theory, Control. --- Systems, Theory of --- Systems science --- Science --- Tumors --- Haematology --- Internal medicine --- Blood --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Philosophy --- Acute leukemia --- Myeloid leukemia
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Provides a visual presentation of myeloproliferative neoplasms and myeloid leukaemia, meeting the needs of haematologists and clinical chemists. Covers clinical presentation, haematological and pathological features, immunophenotyping and cytogenetic and genetic abnormalities. Heavily illustrated throughout with colour photographs and diagrams, this resource fills a gap in the literature and is an essential reference for all haematologists.
Bone marrow -- Diseases -- Diagnosis. --- Bone marrow -- Diseases. --- Bone Marrow -- Pathology. --- Bone Marrow Diseases -- Diagnosis. --- Myeloid leukemia -- Atlases. --- Myeloproliferative disorders -- Atlases. --- Tumors -- Atlases. --- Leukemia --- Bone Marrow Diseases --- Hematologic Diseases --- Neoplasms by Histologic Type --- Myeloproliferative Disorders --- Leukemia, Myeloid --- Neoplasms --- Hemic and Lymphatic Diseases --- Diseases --- Medicine --- Health & Biological Sciences --- Hematological Diseases --- Blood Diseases --- Blood Disease --- Disease, Blood --- Disease, Hematologic --- Disease, Hematological --- Diseases, Blood --- Diseases, Hematologic --- Diseases, Hematological --- Hematologic Disease --- Hematological Disease --- Bone Marrow Disease --- Disease, Bone Marrow --- Diseases, Bone Marrow --- Marrow Disease, Bone --- Marrow Diseases, Bone --- Leucocythaemia --- Leucocythemia --- Leucocythaemias --- Leucocythemias --- Leukemias --- Benign Neoplasms --- Malignancy --- Neoplasia --- Neoplasm --- Neoplasms, Benign --- Cancer --- Tumors --- Benign Neoplasm --- Cancers --- Malignancies --- Neoplasias --- Neoplasm, Benign --- Tumor --- Leukemia, Monocytic, Chronic --- Monocytic Leukemia, Chronic --- Granulocytic Leukemia --- Leukemia, Granulocytic --- Leukemia, Myelocytic --- Leukemia, Myelogenous --- Myelocytic Leukemia --- Myelogenous Leukemia --- Myeloid Leukemia --- Chronic Monocytic Leukemia --- Chronic Monocytic Leukemias --- Granulocytic Leukemias --- Leukemia, Chronic Monocytic --- Leukemias, Chronic Monocytic --- Leukemias, Granulocytic --- Leukemias, Myelocytic --- Leukemias, Myelogenous --- Leukemias, Myeloid --- Monocytic Leukemias, Chronic --- Myelocytic Leukemias --- Myelogenous Leukemias --- Myeloid Leukemias --- Disorder, Myeloproliferative --- Disorders, Myeloproliferative --- Myeloproliferative Disorder --- Histological Type of Neoplasm --- Histological Types of Neoplasms --- Neoplasms by Histological Type --- Neoplasm Histological Type --- Neoplasm Histological Types --- Neoplasms Histological Type --- Neoplasms Histological Types --- Hematology --- Hematologic Neoplasms --- Malignant Neoplasms --- Malignant Neoplasm --- Neoplasm, Malignant --- Neoplasms, Malignant --- Medical Oncology --- Blood and Lymphatic System Disorders
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