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The role of free radicals and oxidative stress in neurological disorders has only recently been recognized, leaving clinical neurologists to seek in vain for information on the subject even in major textbooks. What published information there is may consist of brief reminders of the possible association of superoxidase dismutase with familial amyotrophic lateral sclerosis and nitrous oxide with migraine. With luck they may also find information on the purported role of free radicals in the pathogenesis of traumatic brain injury. Oxidative Stress and Free Radical Damage in Neurology sets the record straight, focusing on clinical and research issues regarding the interplay of free radicals and the human nervous system. Crucially, the chapters cover numerous antioxidants and their possible therapeutic role in neurological disorders. Key illnesses such as epilepsy, multiple sclerosis and Parkinson’s are analyzed, and chapters also examine more general issues such as the link between free radicals and inflammation of the central nervous system. Clinicians and laboratory researchers alike will find that this book augments their understanding not only of the widespread involvement of free radicals in the central nervous system but also of some uncertainties surrounding whether free radical damage in neurology plays a primary or secondary role.

Free radicals (Chemistry) -- Pathophysiology. --- Nervous system -- Diseases -- Etiology. --- Oxidative stress. --- Oxidative stress --- Free radicals (Chemistry) --- Nervous system --- Organic Chemicals --- Diseases --- Stress, Physiological --- Central Nervous System Diseases --- Metabolism --- Inorganic Chemicals --- Metabolic Phenomena --- Chemicals and Drugs --- Physiological Processes --- Nervous System Diseases --- Brain Diseases --- Oxidative Stress --- Free Radicals --- Physiological Phenomena --- Phenomena and Processes --- Medicine --- Health & Biological Sciences --- Neurology --- Pathology --- Pathophysiology --- Etiology --- Neurology. --- Medicine. --- Molecular biology. --- Neurosciences. --- Cell biology. --- Biomedicine. --- Cell Biology. --- Molecular Medicine. --- Neuropsychiatry --- Oxidation-reduction reaction --- Stress (Physiology) --- Cytology. --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Physicians --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Neural sciences --- Neurological sciences --- Neuroscience --- Health Workforce --- Molecular biochemistry --- Molecular biophysics --- Biochemistry --- Biophysics --- Biomolecules --- Systems biology

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The book pertains to unique phenomenological features of a potentially runaway polymerization reaction process that is apparently brought under control through a mass and energy confining mechanism. It integrates the combination of various concepts in order to explain a collection of experimental observations, which includes entrapment of reactive intermediates as well as their energy contents, nucleated thermal hot spots beyond adiabatic rise temperatures, and nanoscale confinement behavior that has been used for fine patterning of polymers. Toward the end, the author of the book will try to

Free radical reactions. --- Polymerization. --- Chemistry --- Physical & Theoretical Chemistry --- Organic Chemistry --- Physical Sciences & Mathematics --- Free radicals (Chemistry) --- Polymerisation --- Polymers --- Polymers and polymerization --- Synthesis of polymers --- Synthesis --- Chemistry. --- Renewable energy resources. --- Physical chemistry. --- Polymers. --- Chemical engineering. --- Industrial engineering. --- Production engineering. --- Renewable energy sources. --- Alternate energy sources. --- Green energy industries. --- Nanotechnology. --- Polymer Sciences. --- Industrial and Production Engineering. --- Physical Chemistry. --- Renewable and Green Energy. --- Industrial Chemistry/Chemical Engineering. --- Radicals (Chemistry) --- Free radical reactions --- Chemical reactions --- Chemistry, Physical organic. --- Chemistry, Industrial --- Engineering, Chemical --- Industrial chemistry --- Engineering --- Chemistry, Technical --- Metallurgy --- Alternate energy sources --- Alternative energy sources --- Energy sources, Renewable --- Sustainable energy sources --- Power resources --- Renewable natural resources --- Agriculture and energy --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Molecular technology --- Nanoscale technology --- High technology --- Management engineering --- Simplification in industry --- Value analysis (Cost control) --- Polymere --- Polymeride --- Macromolecules --- Polymers  . --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Manufacturing engineering --- Process engineering --- Industrial engineering --- Mechanical engineering