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With so many major advances over the past two decades coming through the application of molecular biology and nanotechnology, it is essential that dental research, education, and practice keep pace with the rapid progress of science. In Oral Biology: Molecular Techniques and Applications, expert researchers in the field have provided a selection of in depth methods and techniques optimized for particular applications, which can be readily adapted to particular organisms or areas of interest. Divided into three convenient sections, the book covers the study of saliva, as it is a rich source of biomolecules for study at the molecular level, which may lead to the identification of susceptibility to particular diseases, the study of the microbial inhabitants that share the oral cavity with us, as well as a range of protocols that facilitate assessment of the molecular behavior of oral cells and tissues in health and during disease progression. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Oral Biology: Molecular Techniques and Applications is an ideal resource not only to the new researcher but also to the seasoned laboratory veteran including cell biologists, microbiologists, and any researchers intent on delving into the vital world of oral biology.

Microbiology. --- Pathology. --- Microbial biology --- Biology --- Microorganisms --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive

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Pathology --- Pathology. --- Disease (Pathology) --- Pathologies --- Disease --- pathology --- histopathology --- hematology --- parasitology --- pathology --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- haematology

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Biological interactions of visible light with photosensitizers have been studied for over a century while controlled clinical applications of light and photosensitizers to treat solid tumors, known as photodynamic therapy, have been evolving since the mid 1970’s. In Photodynamic Therapy: Methods and Protocols, leading PDT scientists and clinicians provide the first comprehensive collection of methods and protocols specifically related to relevant mechanistic, dosimetric, preclinical, and clinical procedures used in current PDT research. Reflecting the growing number of studies demonstrating that immunological, tumor microenvironmental, and vascular responses are all contributing to PDT treatment outcomes, the contents of this volume move beyond the more traditional PDT concepts in order to investigate the numerous signal transduction and cell death pathways involved. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes which highlight tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Photodynamic Therapy: Methods and Protocols is an ideal guide for new investigators just starting out in PDT research as well as seasoned investigators changing the direction of their research with the intention of exploring this vital field of study.

Medicine. --- Pathology. --- Molecular Medicine. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Health Workforce --- Biology --- Biomedical Research. --- Biological research --- Biomedical research --- Research.

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Molecular Pathology of Hematolymphoid Diseases The Molecular Pathology Library Series fills the gap between basic science and clinical application. Each user-friendly reference brings together diverse topics about molecular pathogenesis, diagnosis and treatment in one volume. The series serves physicians and healthcare providers in multiple disciplines who need to understand and apply molecular diagnostics and therapy to patient care; residents and fellows who integrate molecular medicine into their curricula and future practice; and basic and translational researchers who must define the impact of their research on clinical medicine.

Blood -- Diseases -- Diagnosis. --- Blood -- Diseases -- Genetic aspects. --- Blood -- Diseases -- Molecular aspects. --- Pathology, Molecular. --- Blood --- Hemic and Lymphatic Diseases --- Hematologic Diseases --- Neoplasms by Site --- Hematologic Neoplasms --- Lymphatic Diseases --- Diseases --- Neoplasms --- Medicine --- Pathology --- Health & Biological Sciences --- Molecular aspects --- Molecular aspects. --- Medicine. --- Pathology. --- Medicine & Public Health. --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Physicians --- Body fluids --- Fear of blood

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Essentials in Bone and Soft-Tissue Pathology is a concise and well-illustrated handbook that captures the salient points of the most common problems in bone and soft-tissue pathology. The volume includes the most important diagnostic features of common musculoskeletal lesions. This book is a short text directed primarily at residents in pathology and other individuals interested in the field of orthopedic pathology, including medical students, orthopedic surgeons, radiologists, and practicing pathologists who do not see these cases on a day to day basis. Jasvir S. Khurana, MD has trained in orthopedic surgery as well as pathology. He trained in Boston at the Massachusetts General Hospital and Tufts New England Medical Center and did a fellowship at the Mayo Clinic. He was on faculty at the University of Pennsylvania and is currently an associate professor in pathology and a surgical pathologist at Temple University in Philadelphia, with a special interest in bone. His research interests include bone tumors and bone biology. He has authored several papers and text books in the field of orthopedic pathology. Edward McCarthy, MD has trained in orthopedic surgery as well as pathology. He trained in Iowa and Maryland where he also did his fellowship in orthopedic pathology. He has been on faculty at Johns Hopkins Hospital for several years where he is currently a professor of pathology. He has received several awards for clinical work and teaching. His clinical and research interests include bone and joint diseases including the use of undecalcified sections for the study of metabolic bone disease. He has authored several papers and text books in the field of orthopedic pathology. Paul J. Zhang, MD trained at the New York University and did a fellowship at the Memorial Sloan-Kettering Cancer Center. He has worked at the Roswell Park Cancer Institute and is currently an associate professor of pathology at the University of Pennsylvania, where he is the director of Bone and Soft-tissue service. His main research interest is in soft-tissue sarcoma where he has authored numerous papers.

Bones -- Diseases -- Diagnosis. --- Bones -- Diseases -- Pathogenesis. --- Soft tissue tumors -- Diagnosis. --- Soft tissue tumors -- Pathogenesis. --- Bones --- Soft tissue tumors --- Musculoskeletal Diseases --- Neoplasms by Site --- Neoplasms --- Diseases --- Bone Diseases --- Soft Tissue Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Musculoskeletal System Diseases --- Pathology --- Pathogenesis --- Diagnosis --- Pathogenesis. --- Diagnosis. --- Soft tissue neoplasms --- Osteology --- Medicine. --- Pathology. --- Medicine & Public Health. --- Tumors --- Musculoskeletal system --- Bone --- Skeleton --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive