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Angiotensins. --- Angiotensins --- Receptors.
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Angiotensins. --- Angiotensins --- Receptors.
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Angiotensins. --- Angiotensins --- Receptors.
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The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlighted the novel roles of a local renin-angiotensin system (RAS) in the pancreas and its clinical relevances; its inapprporiate activation leads to pancreatic endocrine and exocrine disease, notably type 2 diabetes. As such, manipulation of the overactive RAS may improve pancreatic islet cell function, cell mass and insulin sensitivity, as well as enhancing the growth and differentiation of pancreatic stem cells. Blockade of the RAS may be protective against pancreatitis and pancreatic cancer. The research outcome of current progress on the RAS in the pancreas should provide an alternative approach to preventing and treating, as well as curing pancreatic disease. This book discusses the progress of research on the renin-angiotensin system in the pancreas from the science to the bedside, providing a timely review of this expanding area. It consists of ten interrelated chapters covering subjects as: – Structure, physiology and disease of the pancreas – Biochemistry and physiology of the pancreatic renin-angiotensin system – RAS in diabetes, stem cells and pancreatitis This book is of special value to basic and clinical scientists, clinicians, graduate students, as well as novices in this field. .
Pancreas. --- Renin-angiotensin system. --- Renin-angiotensin system --- Pancreas --- Research --- Digestive System --- Digestive System Diseases --- Hemodynamics --- Metabolism --- Diseases --- Science --- Anatomy --- Cardiovascular Physiological Processes --- Metabolic Phenomena --- Biomedical Research --- Renin-Angiotensin System --- Pancreatic Diseases --- Natural Science Disciplines --- Cardiovascular Physiological Phenomena --- Phenomena and Processes --- Disciplines and Occupations --- Circulatory and Respiratory Physiological Phenomena --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Angiotensins --- Renin --- Kidneys --- Physiology. --- Pathophysiology. --- Angiotensin --- Medicine. --- Human physiology. --- Diabetes. --- Gastroenterology. --- Biomedicine. --- Biomedicine general. --- Human Physiology. --- Internal medicine --- Digestive organs --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Human biology --- Medical sciences --- Physiology --- Human body --- Clinical sciences --- Medical profession --- Life sciences --- Pathology --- Physicians --- Aspartic proteinases --- Juxtaglomerular apparatus --- Neuropeptides --- Oligopeptides --- Peptide hormones --- Health Workforce --- Gastroenterology . --- Biomedicine, general.
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The renin angiotensin system plays an essential role on cardiac and vascular functions and their connection in the generation of cardiovascular diseases. Renin Angiotensin System and Cardiovascular Disease covers indispensable aspects such as intracellular signaling, regulation of cell volume in the failing heart, the presence of an intracrine renin angiotensin system, and the influence of prorenin/renin, angiotensin II, angiotensin (1-7) and aldosterone. Furthermore, the role of the mineralocorticoid receptor as an imperative component of the intracrine renin angiotensin system and as a regulator of extracellular action of angiotensin II is described, reinforcing the view that aldosterone inhibitors are helpful in the treatment of heart failure and hypertension. Renin Angiotensin System and Cardiovascular Disease provides readers with an outstanding review of the major topics involving the renin angiotensin system and cardiovascular disease. With contributions by an international panel of experts, Renin Angiotensin System and Cardiovascular Disease presents the most relevant aspects of the role of the renin angiotensin aldosterone system on cardiovascular diseases including hypertension, congestive heart failure, atherosclerosis and diabetes. The volume Editors, Dr. Walmor C. DeMello and Dr. Edward Frohlich, both established specialists in their respective fields, team up to discuss a range of topics from Renin Angiotensin Aldosterone System and Pathobiology of Hypertension to Inhibiting the Renin Angiotensin Aldosterone System in Patients with Heart Failure and Myocardial Infarction.
Angiotensin converting enzyme -- Inhibitors. --- Cardiovascular system -- Diseases -- Prevention. --- Cardiovascular system -- Diseases. --- Renin-angiotensin system --- Cardiovascular system --- Receptors, Angiotensin --- Renin-Angiotensin System --- Physiology --- Cardiovascular Diseases --- Receptors, Peptide --- Receptors, Neuropeptide --- Biological Science Disciplines --- Diseases --- Receptors, G-Protein-Coupled --- Metabolism --- Hemodynamics --- Metabolic Phenomena --- Cardiovascular Physiological Processes --- Receptors, Cell Surface --- Natural Science Disciplines --- Receptors, Neurotransmitter --- Membrane Proteins --- Cardiovascular Physiological Phenomena --- Disciplines and Occupations --- Phenomena and Processes --- Proteins --- Circulatory and Respiratory Physiological Phenomena --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Animal Biochemistry --- Human Anatomy & Physiology --- Medicine --- Health & Biological Sciences --- Renin-angiotensin system. --- Angiography. --- Cardiology. --- Internal medicine. --- Medicine. --- Medicine, Internal --- Blood-vessels --- RA system --- RAA system --- RAAS (Physiology) --- RAS (Physiology) --- Renin-angiotensin-aldosterone axis --- Renin-angiotensin-aldosterone system --- Clinical sciences --- Medical profession --- Radiography --- Angiology. --- Medicine & Public Health. --- Internal Medicine. --- Heart --- Internal medicine --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Diagnosis, Radioscopic --- Radiography, Medical --- Aldosterone --- Angiotensins --- Renin --- Water-electrolyte balance (Physiology) --- Blood pressure --- Regulation --- Diseases. --- Angiology --- Vascular diseases
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