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Heart failure --- Cardiac failure --- Cardiac insufficiency --- Failure, Heart --- Insufficiency, Cardiac --- Heart --- Cardiac arrest --- Etiology. --- Diagnosis. --- Treatment. --- Diseases

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Heart Failure (HF) is the final and common pathway of all cardiovascular diseases. Heart Failure: Bench to Bedside helps address a significant need to develop new paradigms and to identify novel therapeutic targets for this pervasive disease. An authoritative contribution to the field, this book provides a detailed description of new findings and emerging methodologies, as well as a critical clinical evaluation of the complex HF syndrome and future therapies. Heart Failure: Bench to Bedside includes a primer on gene profiling and bioenergetics of the normal heart and a discussion of the molecular, genetic, biochemical and cellular techniques critical to understanding HF. Further chapters discuss cardiac remodeling, oxidative stress, and alterations in other organs and systems that are often associated with HF. Heart Failure: Bench to Bedside thoughtfully evaluates current and forthcoming diagnostic techniques and therapies, pharmaceutical and pharmacogenomic-based individualized medicine, gene and cell-based therapies, and the search for new frontiers. Heart Failure: Bench to Bedside presents a clear view of up-to-date approaches to clinical diagnosis and treatment, as well as offering insightful critiques of original and creative scientific thoughts on post-genomic HF research.

Heart Failure -- Physiopathology. --- Heart Failure -- Therapy. --- Heart failure. --- Translational research. --- Heart failure --- Heart Failure --- Heart Diseases --- Cardiovascular Diseases --- Diseases --- Medicine --- Health & Biological Sciences --- Cardiac failure --- Cardiac insufficiency --- Failure, Heart --- Insufficiency, Cardiac --- Medicine. --- Internal medicine. --- Angiology. --- Cardiology. --- Medicine & Public Health. --- Internal Medicine. --- Heart --- Cardiac arrest --- Angiography. --- Medicine, Internal --- Blood-vessels --- Diagnosis, Radioscopic --- Radiography, Medical --- Internal medicine --- Radiography --- Diseases. --- Angiology --- Vascular diseases

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Over the years, there has been considerable progress in the diagnosis and management of the syndrome of heart failure, the end-stage of most cardiac diseases. While the outlook for heart failure patients is significantly improved, little has yet been achieved in prevention of the condition and much remains to be done to delay disease progression and alleviate symptoms. This cannot be achieved without further high quality research, particularly into the causes of heart failure itself and its progression from other less serious conditions. As heart failure is commonly increasing, there is a need for all medical practitioners to be aware of the early signs and symptoms so early diagnosis and appropriate management can be offered. Heart Failure in Clinical Practice provides a toolkit for clinicians to guide them in the diagnosis and treatment of patients with suspected heart failure. Algorithms and flow diagrams are included to give the reader an illustrated snapshot of the decisions involved in the management of these patients. The more controversial issues mentioned in the chapters of this book aim to stimulate clinicians to progress these ideas.

Cardiac Output, Low. --- Heart Failure -- Etiology. --- Heart Failure -- Physiopathology. --- Heart Failure -- Therapy. --- Heart failure. --- Cardiovascular Diseases --- Heart Diseases --- Heart Failure --- Diseases --- Medicine --- Health & Biological Sciences --- Heart --- Diseases. --- Cardiac diseases --- Heart diseases --- Cardiac failure --- Cardiac insufficiency --- Failure, Heart --- Insufficiency, Cardiac --- Medicine. --- Emergency medicine. --- Public health. --- Health promotion. --- Internal medicine. --- Cardiology. --- Diabetes. --- Medicine & Public Health. --- Internal Medicine. --- Emergency Medicine. --- Health Promotion and Disease Prevention. --- Public Health. --- Cardiology --- Cardiac arrest --- Brittle diabetes --- Diabetes mellitus --- IDDM (Disease) --- Insulin-dependent diabetes --- Ketosis prone diabetes --- Type 1 diabetes --- Carbohydrate intolerance --- Endocrine glands --- Diabetic acidosis --- Glycosylated hemoglobin --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Medicine, Emergency --- Critical care medicine --- Disaster medicine --- Medical emergencies --- Medicine, Internal --- Internal medicine --- Health Workforce --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education

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Heart failure affects over 5 million patients in the United States alone, and is a chronic and debilitating disease. While a number of pharmacologic therapies have shown varying degrees of effectiveness, many recent advances in the treatment of heart failure has focused on device based therapies. In Device Therapy in Heart Failure, William H. Maisel and a panel of authorities on the use and implementation of device based therapies provide a comprehensive overview of the current and developing technologies that are used to treat heart failure. Individual chapters provide an in-depth analysis of devices such as CRT’s and ICD’s, while broader topics such as the pathophysiology of heart failure and its current medical therapies are also discussed. Additional topics include Pacing and Defibrillation for Atrial Arrhythmias, Atrial Fibrillation Ablation, and Percutaneous Treatment of Coronary Artery Disease.

Arrhythmia -- Treatment. --- Cardiac Pacing, Artificial. --- Defibrillators, Implantable. --- Electric countershock. --- Heart Failure -- therapy. --- Heart failure -- Treatment. --- Heart Failure, Congestive -- therapy. --- Pacemaker, Artificial. --- Ventricular Dysfunction -- therapy. --- Heart failure --- Electric Stimulation Therapy --- Electrodes --- Cardiac Pacing, Artificial --- Artificial Organs --- Heart Diseases --- Prostheses and Implants --- Pacemaker, Artificial --- Cardiac Resynchronization Therapy Devices --- Electric Countershock --- Cardiac Resynchronization Therapy --- Heart, Artificial --- Defibrillators --- Heart Failure --- Equipment and Supplies --- Cardiovascular Diseases --- Therapeutics --- Surgical Equipment --- Electrical Equipment and Supplies --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diseases --- Medicine --- Health & Biological Sciences --- Treatment --- Medical instruments and apparatus. --- Apparatus, Medical --- Instruments, Medical --- Medical apparatus --- Medical devices --- Medical products --- Cardiac failure --- Cardiac insufficiency --- Failure, Heart --- Insufficiency, Cardiac --- Treatment. --- Apparatus --- Equipment and supplies --- Instruments --- Medicine. --- Cardiology. --- Medicine & Public Health. --- Biomedical engineering --- Medical supplies --- Scientific apparatus and instruments --- Heart --- Cardiac arrest