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Since the publication of the first edition of "The Mycota Vol. V - Plant Relationships" in 1997, tremendous advances in fungal molecular biology and biochemistry have taken place; and both light and electron microscopical techniques have improved considerably. These new insights led to a better understanding of the relationships between fungi and plants; and a completely revised new edition of Plant Relationships could be produced, providing an up-to-date overview on mutualistic and pathogenic interactions. In 18 chapters internationally acknowledged authors present reviews on fungal lifestyles, mechanisms of their interactions with their host plants, signal perception and transduction, and plant defense responses directed against attack by fungal pathogens. Highlighting the recent developments in fungus-plant interactions, this volume is indispensable for researchers, lecturers and students in microbiology, mycology and plant sciences, including plant pathology.

Genetics --- General microbiology --- genomen (geneeskunde) --- systematische plantkunde --- Plant physiology. Plant biophysics --- microbiologie --- medische genetica --- fungi

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Handbook of Behavior Genetics Edited by Yong-Kyu Kim With the mapping of the human genome, behavior genetics attracted interest as a new lens for studying complex behavior patterns and disorders. This specialty has evolved into an emergent common ground for scientists of diverse fields, including psychology, psychiatry, neurology, biochemistry, and endocrinology as well as genetics. The Handbook of Behavior Genetics provides psychology, psychiatry, and genetics students with a solid research framework on the role of genes and other factors in a variety of intricate behaviors. Internationally-known experts begin each chapter with an overview of a subject and discuss its latest issues, advances, and controversies, and emerging areas of importance. The genetics of personality, pathology, and cognition are examined, with topics as diverse as childhood temperament, Down syndrome, exercise behavior, handedness, and speech disorders. Through these findings, contributors identify clear directions for the field in its next decade. A sampling of the Handbook's coverage: Methods and models: biometrical, QTL, animal models. Twin studies of mental ability. Genetic and environmental influences on sexual orientation. The genetics of pathological conditions, including ADHD, antisocial behavior, childhood depression, schizophrenia, and autism. Attention and working memory. Substance use and abuse disorders. Cognitive aging. The Handbook of Behavior Genetics brings new clarity to the ongoing study of nature and nurture, and is a suitable text for graduate and doctoral students in this robust field.

Affective and dynamic functions --- Human genetics --- Psychiatry --- biopsychologie --- medische genetica --- psychiatrie --- genetica

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Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer's disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: Neuropsychological Endophenotypes and Biomarkers  (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers , Metabolic and Peripheral Biomarkers  and Molecular Genetic and Genomic Markers . The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.

Human biochemistry --- Human genetics --- Psychiatry --- Neuropathology --- medische biochemie --- neurologie --- medische genetica --- psychiatrie --- biochemie --- hersenen --- genetica

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The availability of new molecular approaches to the selection of drug therapy is an emerging need, as the traditional approach based on the evaluation of patient and tumor characteristics is clearly far from optimal. Many, and in most cases the majority of treated patients do not have significant benefits from the treatment while they often experience moderate to severe toxicities. In "Pharmacogenomics, Anticancer Drug Discovery, and Response," edited by Federico Innocenti, readers will find a series of chapters addressing the role of genomic information in cancer therapy and in drug development representing a unique source, as it describes experimental approaches, statistical strategies, and clinical examples of the application of genomic medicine in oncology. This book provides the most comprehensive body of knowledge on the role of genetic and genomic variation in the individualization of drug therapies in cancer patients.

Pharmacology. Therapy --- Oncology. Neoplasms --- Human genetics --- medische genetica --- farmacie --- farmacologie --- genomics --- genetica --- toxicologie --- oncologie

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Epidermolysis bullosa (EB) is a heterogenous group of genodermatoses characterized by the formation of blisters and erosions on skin and mucous membrans from birth on. The cause are mutations in the genes of structural proteins of the junction between epidermis and dermis. This book deals with the treatment of this skin disease itself and its many extracutaneous complications. There is no previous book which has been focused on the therapy and it will be based on evidence-based data derived from the world´s largest cohort of inherited EB-patients, the American EB Registry. An important chapter will discuss gene therapy in hereditary EB which has been recently successfully performed within a localized skin site on a single EB patient as a proof-of-principle test. Given its unique collective contents, the monograph will provide the primary source for clinical informations of this oftentimes severe multiorgan disease.

Paediatrics --- Human genetics --- Pathological dermatology --- Surgery --- Human medicine --- medische genetica --- geneeskunde --- dermatologie --- genetica --- pediatrie --- chirurgie