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Vibrio cholerae, the causative organism of the disease Cholera, colonizes the small intestine and produces several different toxins among which the enterotoxin, or more widely known as cholera toxin (CT), happens to be the major virulence determinant that is responsible for the diarrheal syndrome. This book provides for the first time comprehensive and up-to-date information about all the toxins of Vibrio cholerae, their physical and chemical structures, their biosynthesis and its genetic regulation, their physiology, the molecular biology of their interactions with the host as well as their role in the development of an appropriate and effective cholera vaccine. It also offers relevant and necessary background information on the basic biology of the Vibrio cholerae cell and cholera bacteriophages.

Cholera toxin. --- Cholera toxin --- Bacterial Toxins --- ADP Ribose Transferases --- Enterotoxins --- Toxins, Biological --- Pentosyltransferases --- Biological Factors --- Glycosyltransferases --- Chemicals and Drugs --- Transferases --- Enzymes --- Enzymes and Coenzymes --- Cholera Toxin --- Biology --- Medicine --- Health & Biological Sciences --- Microbiology & Immunology --- Infectious Diseases --- Enterotoxins. --- Enterotoxin --- Cholera enterotoxin --- Cholera exotoxin --- Choleragen --- Choleragenoid --- CT (Cholera toxin) --- CTX (Cholera toxin) --- Procholeragenoid --- Vibrio cholerae enterotoxin --- Medicine. --- Medical microbiology. --- Pharmacology. --- Food --- Biochemistry. --- Cell biology. --- Microbiology. --- Biomedicine. --- Medical Microbiology. --- Food Science. --- Biochemistry, general. --- Cell Biology. --- Pharmacology/Toxicology. --- Biotechnology. --- Bacterial toxins --- NAD-ADP-ribosyltransferase --- Food science. --- Cytology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Science --- Microbial biology --- Microorganisms --- Toxicology --- Composition --- Food—Biotechnology. --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Physiological effect

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Gastroenterology. --- Gastrointestinal Diseases. --- Gastrointestinal system --- Diseases. --- Functional Gastrointestinal Disorders --- Gastrointestinal Disorders, Functional --- Cholera Infantum --- Disease, Gastrointestinal --- Diseases, Gastrointestinal --- Disorder, Functional Gastrointestinal --- Disorders, Functional Gastrointestinal --- Functional Gastrointestinal Disorder --- Gastrointestinal Disease --- Gastrointestinal Disorder, Functional --- Infantum, Cholera --- Gastroenterology --- Gastroentérologie --- Tractus gastro-intestinal --- Maladies --- Gastrointestinal Diseases --- Internal medicine --- Digestive organs --- Diseases --- Gastrointestinal Disorders --- Gastrointestinal Disorder

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Nature Reviews Gastroenterology & Hepatology is a peer-reviewed journal for gastroenterologists, hepatologists and affiliated health-care professionals. The journal delivers timely interpretations of key developments in gastroenterology, hepatology and related areas of study. Nature Reviews Gastroenterology & Hepatology is published monthly in print and online and includes commissioned news, commentary and opinion pieces and comprehensive reviews. Articles are subject to rigorous peer-review and/or review by in-house editors. Topics covered include the pathology, diagnosis and treatment of diseases of the gastrointestinal tract, liver, pancreas, gall bladder and biliary tract, such as functional gastrointestinal disorders, inflammatory diseases, cancer, infection and nutritional disorders.

Gastroenterology --- Digestive organs --- Gastroenterology. --- Gastrointestinal Diseases. --- Diseases --- Diseases. --- Functional Gastrointestinal Disorders --- Gastrointestinal Disorders, Functional --- Cholera Infantum --- Disease, Gastrointestinal --- Diseases, Gastrointestinal --- Disorder, Functional Gastrointestinal --- Disorders, Functional Gastrointestinal --- Functional Gastrointestinal Disorder --- Gastrointestinal Disease --- Gastrointestinal Disorder, Functional --- Infantum, Cholera --- Alimentary canal --- Digestive system diseases --- Alimentary system --- Digestive system --- Organs (Anatomy) --- Internal medicine --- Gastrointestinal Disorders --- Gastrointestinal Disorder --- Medicine --- Hepatology --- Medicine/Public Health, general --- Biomedicine, general --- Health Workforce --- Gastrointestinal Diseases

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Medical personnel --- Deglutition disorders --- Evidence, Expert --- Medical jurisprudence --- Jurisprudence --- Pharyngeal Diseases --- Esophageal Diseases --- Otorhinolaryngologic Diseases --- Social Control, Formal --- Gastrointestinal Diseases --- Sociology --- Health Care Economics and Organizations --- Diseases --- Digestive System Diseases --- Social Sciences --- Health Care --- Anthropology, Education, Sociology and Social Phenomena --- Expert Testimony --- Deglutition Disorders --- Malpractice --- Law - U.S. --- Law, Politics & Government --- Law - U.S. - General --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Science, Social --- Sciences, Social --- Social Science --- Digestive System Disorders --- Hepatobiliary Diseases --- Hepatobiliary Disorders --- Digestive System Disease --- Digestive System Disorder --- Hepatobiliary Disease --- Hepatobiliary Disorder --- System Disorders, Digestive --- Healthcare Economics and Organizations --- Health Care Economics --- Health Economics --- Healthcare Economics --- Care Economic, Health --- Economic, Health --- Economic, Health Care --- Economic, Healthcare --- Economics, Health Care --- Health Care Economic --- Health Economic --- Healthcare Economic --- General Social Development and Population --- Functional Gastrointestinal Disorders --- Gastrointestinal Disorders, Functional --- Cholera Infantum --- Gastrointestinal Disorders --- Disease, Gastrointestinal --- Diseases, Gastrointestinal --- Functional Gastrointestinal Disorder --- Gastrointestinal Disease --- Gastrointestinal Disorder --- Gastrointestinal Disorder, Functional --- Gastroenterology --- Regulation --- Social Control --- Control, Social --- Controls, Social --- Formal Social Control --- Formal Social Controls --- Regulations --- Social Controls --- Public Policy --- ENT Diseases --- Otolaryngological Diseases --- Otorhinolaryngologic Disease --- Otorhinolaryngological Disease --- Otolaryngologic Diseases --- Disease, ENT --- Disease, Otolaryngologic --- Disease, Otolaryngological --- Disease, Otorhinolaryngologic --- Disease, Otorhinolaryngological --- Diseases, ENT --- Diseases, Otolaryngologic --- Diseases, Otolaryngological --- Diseases, Otorhinolaryngologic --- Diseases, Otorhinolaryngological --- ENT Disease --- Otolaryngologic Disease --- Otolaryngological Disease --- Otorhinolaryngological Diseases --- Otolaryngology --- Disease, Esophageal --- Diseases, Esophageal --- Esophageal Disease --- Diseases of Pharynx --- Pharynx Diseases --- Disease, Pharyngeal --- Disease, Pharynx --- Diseases, Pharyngeal --- Diseases, Pharynx --- Pharyngeal Disease --- Pharynx Disease --- Constitutional Law --- Court Decision --- Law --- Legal Aspects --- Legal Obligations --- Legal Status --- State Interest --- Litigation --- Medical Jurisprudence --- Aspect, Legal --- Aspects, Legal --- Constitutional Laws --- Court Decisions --- Decision, Court --- Decisions, Court --- Interest, State --- Interests, State --- Jurisprudence, Medical --- Law, Constitutional --- Laws --- Laws, Constitutional --- Legal Aspect --- Legal Obligation --- Litigations --- Obligation, Legal --- Obligations, Legal --- State Interests --- Status, Legal --- Defamation --- Lawyers --- Forensic medicine --- Injuries (Law) --- Legal medicine --- Forensic sciences --- Medicine --- Medical laws and legislation --- Dysphagia --- Dysphagy --- Esophagus --- Ingestion disorders --- Health care personnel --- Health care professionals --- Health manpower --- Health personnel --- Health professions --- Health sciences personnel --- Health services personnel --- Healthcare professionals --- Medical manpower --- Professional employees --- Negligence --- Negligence, Professional --- Liability, Legal --- Medical Errors --- Professional Misconduct --- Esophageal Dysphagia --- Oropharyngeal Dysphagia --- Swallowing Disorders --- Deglutition Disorder --- Disorders, Deglutition --- Dysphagia, Esophageal --- Dysphagia, Oropharyngeal --- Swallowing Disorder --- Expert Opinion --- Expert Witness --- Expert Opinions --- Expert Testimonies --- Expert Witnesses --- Opinion, Expert --- Testimony, Expert --- Witness, Expert --- Witnesses, Expert