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Macromolecular drugs hold the promise of becoming new therapeutics for several major disorders, including cancer and cardiovascular disease. This incredible potential is explored in Macromolecular Drug Delivery, a volume which gives a wide-ranging overview of contemporary methods used in the field, and which addresses the limitations presented by a lack of safe and efficient drug delivery strategies. Chapters offer information on both in vitro and in vivo methods of macromolecular delivery, thus appealing to a broad scientific audience. Composed in the highly successful Methods in Molecular Biology™ series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and cutting-edge, Macromolecular Drug Delivery offers a platform for interdisciplinary collaboration, which should provide opportunities for new discoveries at the interface between disciplines. Ultimately, this cooperation will lead to the use of macromolecular drugs as novel diagnostic tools and, even more importantly, as a means to revolutionize the way we view and treat diseases.

Toxicology. --- Biochemical engineering. --- Pharmacy. --- Pharmacology/Toxicology. --- Biochemical Engineering. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Chemistry --- Drugs --- Materia medica --- Toxicology

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Through the study and application of bioluminescence, scientists have painstakingly harnessed a powerful tool that enables us to seek a deeper understanding of the complex mechanisms underpinning so many vital biologic systems. In this fully revised and updated second edition of Bioluminescence: Methods and Protocols, expert researchers contribute a readable and utilitarian compilation of the newest and most innovative techniques that have emerged in this rapidly expanding and progressively diverse field including methods to assess cell trafficking, protein-protein interactions, intracellular signaling, and apoptosis. Also opening up the possibility to visualize and quantify biological mechanisms in real-time and in in vivo settings, the volume also describes the in vivo study of bacterial or viral infections, transplanted cells, stem cells proliferation, vascular flow, and tumors. Written in the highly successful Methods in Molecular Biology™ series format, chapters include brief introductions to their respective topics, lists of the necessary materials, equipment, and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Bioluminescence: Methods and Protocols, Second Edition provides protocols that are detailed enough to be followed and adapted by scientific teams who have no previous expertise in bioluminescence in order to foster the potentially numerous breakthroughs and new applications from basic to applied science and medicine that must continue to be developed.

Biochemistry. --- Biochemical engineering. --- Biochemistry, general. --- Biological and Medical Physics, Biophysics. --- Biochemical Engineering. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Composition

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Even though there is no generally accepted definition of nanotechnologies to be defined as distinct discipline there is an emerging consensus that their advent and development is a growing in importance factor of the contemporary and future technological civilization. One of these most fundamental issues we are confronted with is the compatibility with life itself. From single cell organisms to humans, carbon is a key building block of all molecular structures of life. In contrast the man created electronic industry to build on other elements, of which silicon is the most common. Both carbon and silicon create molecular chains, although different in their internal structure. All life is built from carbon-based chains. As long as the man built technological products do not directly interfere with the physiology of life the associated risks from them are relatively easy to identify. They are primarily in the environmental pollution and the possibility of upsetting the natural balance of biocoenosis, on a planetary scale. The basic life functions are still not directly subverted. We can use TV, computers, drive cars and use other technological utilities without fear of direct interference with our cellular functions. This is in particular because all these technological utilities are many orders of magnitude larger than typical scales of biological activity. Most of biological activity, from fermentative catalysis to DNA replication takes place on nanoscale. The situation is radically different when the technological goals are building nanoscale size products. All biological processes take place on nanoscale.

Nanotechnology -- Environmental aspects -- Congresses. --- Nanotechnology -- Social aspects -- Congresses. --- Nanotechnology --- Environmental aspects. --- Social aspects. --- Molecular technology --- Nanoscale technology --- Chemistry. --- Biotechnology. --- Biochemical engineering. --- Chemistry, Physical and theoretical. --- Nanochemistry. --- Philosophy. --- Biochemical Engineering. --- Philosophy of Technology. --- Theoretical and Computational Chemistry. --- Mental philosophy --- Humanities --- Nanoscale chemistry --- Chemistry, Analytic --- Nanoscience --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Chemistry --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Genetic engineering --- Physical sciences --- High technology --- Analytical chemistry --- Social aspects --- Environmental aspects

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Climate change, environmental impact and declining natural resources are driving scientific research and novel technical solutions. Green Energy and Technology serves as a publishing platform for scientific and technological approaches to "green" - i.e., environmentally friendly and sustainable - technologies. While the main focus lies on energy and power supply, the series also covers green solutions in industrial engineering and engineering design. Green Energy and Technology is a monograph series addressing researchers, advanced students and technical consultants, as well as decision makers in industry and politics. The level presentation ranges from instructional to highly technical. The modern world is facing three critical problems: high fuel prices, climate change, and air pollution. Biohydrogen: For Future Engine Fuel Demands covers the production, purification, storage, pipeline transport, usage, and safety of biohydrogen. Hydrogen promises to be the most significant fuel source of the future, due to its global availability and the fact that water is its only by-product. Biofuels such as bioethanol, biodiesel, bio-oil, and biohydrogen are produced using technologies for thermochemically and biologically converting biomass. Hydrogen fuel production technologies can make use of either non-renewable sources, or renewable sources such as wind, solar, and biorenewable resources. Biohydrogen: For Future Engine Fuel Demands reviews all of the modern biomass-based transportation fuels, including bioethanol, biodiesel, biogas, biohydrogen, and fuel cells. The book also discusses issues of biohydrogen economy, policy and environmental impact. Biohydrogen looks set to be the fuel of choice in the future, replacing both fossil fuels and biorenewable liquid fuels.

Hydrogen --Biotechnology. --- Hydrogen --- Health & Biological Sciences --- Biomedical Engineering --- Biotechnology --- Biotechnology. --- Chemistry. --- Renewable energy resources. --- Biochemical engineering. --- Renewable energy sources. --- Alternate energy sources. --- Green energy industries. --- Environmental engineering. --- Biochemical Engineering. --- Renewable and Green Energy. --- Environmental Engineering/Biotechnology. --- Chemical engineering --- Genetic engineering --- Environmental control --- Environmental effects --- Environmental stresses --- Engineering --- Environmental health --- Environmental protection --- Pollution --- Sustainable engineering --- Green energy industries --- Energy industries --- Alternate energy sources --- Alternative energy sources --- Energy sources, Renewable --- Sustainable energy sources --- Power resources --- Renewable natural resources --- Agriculture and energy --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Physical sciences

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As one of the eighteen field-specific reports comprising the comprehensive scope of the strategic general report of the Chinese Academy of Sciences, this sub-report addresses long-range planning for developing science and technology in the field of bio-hylic and biomass resources. They each craft a roadmap for their sphere of development to 2050. In their entirety, the general and sub-group reports analyze the evolution and laws governing the development of science and technology, describe the decisive impact of science and technology on the modernization process, predict that the world is on the eve of an impending S&T revolution, and call for China to be fully prepared for this new round of S&T advancement. Based on the detailed study of the demands on S&T innovation in China's modernization, the reports draw a framework for eight basic and strategic systems of socio-economic development with the support of science and technology, work out China's S&T roadmaps for the relevant eight basic and strategic systems in line with China's reality, further detail S&T initiatives of strategic importance to China's modernization, and provide S&T decision-makers with comprehensive consultations for the development of S&T innovation consistent with China's reality. Supported by illustrations and tables of data, the reports provide researchers, government officials and entrepreneurs with guidance concerning research directions, the planning process, and investment. Founded in 1949, the Chinese Academy of Sciences is the nation's highest academic institution in natural sciences. Its major responsibilities are to conduct research in basic and technological sciences, to undertake nationwide integrated surveys on natural resources and ecological environment, to provide the country with scientific data and consultations for government's decision-making, to undertake government-assigned projects with regard to key S&T problems in the process of socio-economic development, to initiate personnel training, and to promote China's high-tech enterprises through its active engagement in these areas.

Biomass energy --- Renewable energy sources --- Renewable energy resources. --- Biochemical engineering. --- Renewable energy sources. --- Alternate energy sources. --- Green energy industries. --- Economic policy. --- Economics. --- R & D/Technology Policy. --- Biochemical Engineering. --- Renewable and Green Energy. --- Alternate energy sources --- Alternative energy sources --- Energy sources, Renewable --- Sustainable energy sources --- Power resources --- Renewable natural resources --- Agriculture and energy --- Bio-energy (Biomass energy) --- Bioenergy (Biomass energy) --- Biofuels --- Biological fuels --- Energy, Biomass --- Microbial energy conversion --- Energy conversion --- Fuel --- Energy crops --- Microbial fuel cells --- Refuse as fuel --- Waste products as fuel --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Economic nationalism --- Economic planning --- National planning --- State planning --- Economics --- Planning --- National security --- Social policy