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This is the first comprehensive book on human/animal gene responses to RNA viral infections, including prevalent, emerging and re-emerging RNA viruses such as HIV, SARS-CoV, West Nile virus, influenza virus and many others. Human gene responses are reviewed by leading virologists worldwide in the following aspects: (i) the altered gene expression profiles at the transcriptional and translational levels detected with cutting-edge technologies such as cDNA microarray and proteomics; (ii) host innate and adapted immune responses to viral replication in target organs; (iii) virus-activated signal

RNA viruses. --- Viral genetics.

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Divided into two major sections, this volume synthesizes recent findings in this fast-moving field while also reviewing accepted knowledge. The first part focuses on the antiviral signaling pathways in the host, including specific pattern recognition receptors (PRRs) and how these cellular alarms signal the innate immune response. The second section examines the ways in which specific major RNA virus families interact with, activate, and elude these signaling pathways and responses.

RNA viruses. --- Natural immunity. --- Cellular signal transduction. --- Virus diseases --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Cellular control mechanisms --- Information theory in biology --- Disease resistance --- Host resistance --- Innate immunity --- Innate resistance --- Native immunity --- Natural resistance --- Nonspecific immunity --- Resistance to disease --- Immunity --- Riboviruses --- Viruses, RNA --- Viruses --- Immunological aspects. --- RNA Viruses --- Immunity, Innate --- Signal Transduction --- Virus à ARN --- Immunité naturelle --- Transduction du signal cellulaire --- Maladies à virus --- immunology. --- Immunologie

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In West Nile Encephalitis Virus Infection, leading scientists and researchers discuss the West Nile virus, a neurotropic flavivirus that has emerged globally as a primary cause of viral encephalitis. Its appearance in the Western Hemisphere in 1999, and the corresponding increase in global disease burden over the last decade has been accompanied by intensive study, including the entry of many scientists into the field. Breakthroughs have been made in understanding the unique transmission pattern between the vector and the multiple avian and mammalian hosts and targets. While the topics in this book are focused on the West Nile virus, they are broad in scope ranging from understanding vector transmission patterns to the dynamics of structural transitions of proteins on the surface of the virion. The editor and contributors of West Nile Encephalitis Virus Infection offer their expertise in this up-to-date and cutting-edge anthology, which will be of broad use to readers from a variety of backgrounds including clinical infectious disease, epidemiology, virology, immunology, and vector biology.

Emerging infectious diseases. --- Immune response. --- Medicine. --- Microbiology. --- West Nile fever -- Pathogenesis. --- West Nile virus. --- West Nile virus --- West Nile fever --- Immune response --- West Nile Fever --- Encephalitis, Arbovirus --- Encephalitis Viruses, Japanese --- Flavivirus Infections --- Flavivirus --- Encephalitis, Viral --- Arbovirus Infections --- RNA Virus Infections --- Encephalitis Viruses --- Flaviviridae Infections --- Encephalitis --- Virus Diseases --- RNA Viruses --- Flaviviridae --- Central Nervous System Infections --- Central Nervous System Viral Diseases --- Diseases --- Vertebrate Viruses --- Viruses --- Central Nervous System Diseases --- Organisms --- Nervous System Diseases --- Communicable Diseases --- Microbiology & Immunology --- Public Health --- Biology --- Health & Biological Sciences --- Pathogenesis --- Pathogenesis. --- West Nile encephalitis --- West Nile virus disease --- West Nile virus infection --- Egypt 101 virus --- Kunjin virus --- Immunology. --- Virology. --- Infectious diseases. --- Epidemiology. --- Biomedicine. --- Infectious Diseases. --- Biomedicine general. --- Flaviviruses --- Epidemic encephalitis --- Flaviviral diseases --- Immunology --- Medical virology. --- Microbial biology --- Microorganisms --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Immunobiology --- Life sciences --- Serology --- Medical microbiology --- Virology --- Virus diseases --- Public health --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Biomedicine, general. --- Microbiology

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This book contains comprehensive and updated information on how to perform Avian Influenza and Newcastle Disease diagnosis from the suspicion in the field to the characterisation of isolates. It provides guidelines to outbreak management, field investigation, necropsy techniques, sampling methods and complete laboratory diagnosis, including molecular methods. The outstanding images collected from field outbreaks, including clinical and pathological findings, and the selection of laboratory protocols make this publication unique. It will therefore be an invaluable tool for all veterinarians, scientists, animal health professionals, and public health officials involved in the management of these infections.                           .

Avian influenza. --- Avian influenza --- Newcastle disease --- Poultry --- Influenza in Birds --- Influenza A virus --- Newcastle Disease --- Disease Outbreaks --- Influenzavirus A --- Bird Diseases --- Meat --- Avulavirus Infections --- Animals, Domestic --- Orthomyxoviridae Infections --- Public Health --- Poultry Diseases --- Birds --- Animal Diseases --- RNA Virus Infections --- Orthomyxoviridae --- Vertebrates --- Animal Population Groups --- Food --- Environment and Public Health --- Paramyxoviridae Infections --- Animals --- RNA Viruses --- Health Care --- Mononegavirales Infections --- Chordata --- Virus Diseases --- Diseases --- Food and Beverages --- Eukaryota --- Vertebrate Viruses --- Technology, Industry, Agriculture --- Viruses --- Organisms --- Medicine - General --- Veterinary Medicine --- Health & Biological Sciences --- Medicine --- Diagnosis --- Epidemiology --- Virus diseases --- Diagnosis. --- Epidemiology. --- Virus diseases. --- Virus diseases in poultry --- Avian pneumoencephalitis --- Fowl pest --- Avian flu --- Bird flu --- Fowl plague --- Influenza in birds --- Medicine. --- Laboratory medicine. --- Virology. --- Health promotion. --- Infectious diseases. --- Veterinary medicine. --- Biomedicine. --- Laboratory Medicine. --- Veterinary Medicine. --- Health Promotion and Disease Prevention. --- Infectious Diseases. --- Influenza --- Medical laboratories. --- Emerging infectious diseases. --- Medical virology. --- Veterinary Medicine/Veterinary Science. --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Farriery --- Large animal medicine --- Large animal veterinary medicine --- Livestock medicine --- Veterinary science --- Animal health --- Domestic animals --- Livestock --- Medical microbiology --- Virology --- Diagnosis, Laboratory --- Health facilities --- Laboratories --- Losses --- Health Workforce --- Microbiology --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education --- Clinical medicine --- Clinical pathology --- Diagnostic laboratory tests --- Laboratory diagnosis --- Laboratory medicine --- Medical laboratory diagnosis