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Book
Regulatory Networks in Stem Cells
Author:
ISBN: 1603272267 9786612036347 1282036343 1603272275 Year: 2009 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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Abstract

This book ambitiously incorporates all the latest and essential subjects on molecular regulation in embryonic, tissue, and cancer stem cells. The chapter on pathology and therapy is also fairly informative. I highly appreciate rigorous effort by all the editors and contributors, and strongly recommend this book to experts as well as students - Dr. Shinya Yamanaka, Kyoto University, Japan This new volume provides a broad overview of the regulation of stem cell renewal and differentiation from a diverse panel of expert authors. The chapters cover a remarkable range of topics, from molecular biology and model systems to translational and clinical implications of stem cell research. The book will be useful to both students and experienced researchers in the field. - Dr. Martin Pera, University of Southern California, Los Angeles, CA. USA. The application of stem cell 'thinking' and stem cell science to the biology of development, to tissue homeostasis, and to the generation of cancers has resulted in the explosion of new experiments and new models over the past several years. The rate of knowledge accumulation exceeds the abilities of most scientists, and especially aging scientists, to digest by reading the primary literature. Here Rajasekhar and Vemuri have brought together essays and reviews by world leaders in all areas of stem cell research--tissue and organ [adult] stem and progenitor cells, cancer stem cells, classical embryonic pluripotent stem cells, and pluripotent stem cells derived by nuclear reprogramming of adult somatic mature cell nuclei. It even covers the fast breaking field of induced pluripotent stem [iPS] cells, somatic cells that were reprogrammed by the transfection of as little as 3 genes whose gene products can re-set the genome of a mature cell to that of a pluripotent cell. The potentials of all of these areas to study and begin to understand human developmental biology, to produce from patients with genetic diseases pluripotent stem cells that can make all of the cell types affected in the disease, and the obvious translational attempts with tissue and organ stem cells promises to make these approaches, and the reviews in this book, the center of research in regenerative medicine. The identification of cancer stem cell in those cancers that have them [not cancers of stem cells, but the intratumoral cell subset that regenerates the entire tumor while self-renewing] will certainly help provide targets for drug therapies and novel imaging agents in the identified signal transduction pathways they use; and immunotherapy targets by the novel proteins and peptides [at least]that are created by mutations, translocations, and splicing anomalies central to the oncogenic progression in these cancer stem cells. The book is an essential addition to the libraries of scientists and institutions that do and teach stem cell research. I commend the editors and authors for an excellent and exciting book. - Irv Weissman MD, Stanford University.

Keywords

Cell metabolism --Regulation. --- Stem cells. --- Stem cells --- Cell metabolism --- Physiology --- Cell Physiological Processes --- Stem Cells --- Cell Physiological Phenomena --- Biological Science Disciplines --- Cells --- Anatomy --- Phenomena and Processes --- Natural Science Disciplines --- Disciplines and Occupations --- Cytology --- Biology --- Health & Biological Sciences --- Regulation --- Natural Sciences --- Physical Sciences --- Discipline, Natural Science --- Disciplines, Natural Science --- Natural Science --- Natural Science Discipline --- Physical Science --- Science, Natural --- Science, Physical --- Sciences, Natural --- Sciences, Physical --- Anatomies --- Cell --- Biologic Sciences --- Biological Science --- Science, Biological --- Sciences, Biological --- Biological Sciences --- Life Sciences --- Biologic Science --- Biological Science Discipline --- Discipline, Biological Science --- Disciplines, Biological Science --- Life Science --- Science Discipline, Biological --- Science Disciplines, Biological --- Science, Biologic --- Science, Life --- Sciences, Biologic --- Sciences, Life --- Cell Physiological Phenomenon --- Cell Physiological Process --- Physiology, Cell --- Cell Physiology --- Phenomena, Cell Physiological --- Phenomenon, Cell Physiological --- Physiological Process, Cell --- Physiological Processes, Cell --- Process, Cell Physiological --- Processes, Cell Physiological --- Colony-Forming Unit --- Colony-Forming Units --- Mother Cells --- Progenitor Cells --- Cell, Mother --- Cell, Progenitor --- Cell, Stem --- Cells, Mother --- Cells, Progenitor --- Cells, Stem --- Colony Forming Unit --- Colony Forming Units --- Mother Cell --- Progenitor Cell --- Stem Cell --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- physiology --- Metabolism --- Medicine. --- Human genetics. --- Cell biology. --- Developmental biology. --- Neurobiology. --- Biomedicine. --- Human Genetics. --- Cell Biology. --- Developmental Biology. --- Cytology. --- Cell biology --- Cellular biology --- Cytologists --- Neurosciences --- Development (Biology) --- Growth --- Ontogeny --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology

First Signals
Author:
ISBN: 1282458469 9786612458460 1400830583 9781400830589 9780691070377 0691070377 0691070377 0691070385 9780691070384 Year: 2009 Publisher: Princeton, NJ

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Abstract

The enormous recent success of molecular developmental biology has yielded a vast amount of new information on the details of development. So much so that we risk losing sight of the underlying principles that apply to all development. To cut through this thicket, John Tyler Bonner ponders a moment in evolution when development was at its most basic--the moment when signaling between cells began. Although multicellularity arose numerous times, most of those events happened many millions of years ago. Many of the details of development that we see today, even in simple organisms, accrued over a long evolutionary timeline, and the initial events are obscured. The relatively uncomplicated and easy-to-grow cellular slime molds offer a unique opportunity to analyze development at a primitive stage and perhaps gain insight into how early multicellular development might have started. Through slime molds, Bonner seeks a picture of the first elements of communication between cells. He asks what we have learned by looking at their developmental biology, including recent advances in our molecular understanding of the process. He then asks what is the most elementary way that polarity and pattern formation can be achieved. To find the answer, he uses models, including mathematical ones, to generate insights into how cell-to-cell cooperation might have originated. Students and scholars in the blossoming field of the evolution of development, as well as evolutionary biologists generally, will be interested in what Bonner has to say about the origins of multicellular development--and thus of the astounding biological complexity we now observe--and how best to study it.

Keywords

Cell interaction. --- Cells -- Evolution. --- Developmental biology. --- Developmental cytology. --- Cell Differentiation --- Signal Transduction --- Biological Evolution --- Genetic Processes --- Cell Physiological Processes --- Biochemical Processes --- Biological Processes --- Biochemical Phenomena --- Biological Phenomena --- Cell Physiological Phenomena --- Chemical Processes --- Genetic Phenomena --- Phenomena and Processes --- Chemical Phenomena --- Biophysics --- Biology --- Health & Biological Sciences --- Biologic Phenomena --- Biological Phenomenon --- Biological Process --- Phenomena, Biological --- Phenomena, Biologic --- Phenomenon, Biological --- Process, Biological --- Processes, Biological --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Molecular Biology --- Cell Physiological Phenomenon --- Cell Physiological Process --- Physiology, Cell --- Cell Physiology --- Phenomena, Cell Physiological --- Phenomenon, Cell Physiological --- Physiological Process, Cell --- Physiological Processes, Cell --- Process, Cell Physiological --- Processes, Cell Physiological --- Cells --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Evolution, Biological --- Sociobiology --- Receptor Mediated Signal Transduction --- Signal Transduction Pathways --- Signal Transduction Systems --- Cell Signaling --- Receptor-Mediated Signal Transduction --- Signal Pathways --- Pathway, Signal --- Pathway, Signal Transduction --- Pathways, Signal --- Pathways, Signal Transduction --- Receptor-Mediated Signal Transductions --- Signal Pathway --- Signal Transduction Pathway --- Signal Transduction System --- Signal Transduction, Receptor-Mediated --- Signal Transductions --- Signal Transductions, Receptor-Mediated --- System, Signal Transduction --- Systems, Signal Transduction --- Transduction, Signal --- Transductions, Signal --- Cell Communication --- Receptor-CD3 Complex, Antigen, T-Cell --- Receptor Cross-Talk --- Feedback, Physiological --- Gasotransmitters --- Differentiation, Cell --- Cell Differentiations --- Differentiations, Cell --- Embryo, Mammalian --- Gene Expression Regulation --- Cell Lineage --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- physiology --- Cell interaction --- Developmental biology --- Developmental cytology --- 57.017.22 --- 575.853 --- Cell evolution --- Cellular evolution --- Evolution (Biology) --- Evolution --- 575.853 The cell and subcellular structure --- The cell and subcellular structure --- 57.017.22 Origin. Formation. Precursors --- Origin. Formation. Precursors --- Cytology --- Development (Biology) --- Growth --- Ontogeny --- Cell-cell interaction --- Cell communication --- Cellular communication (Biology) --- Cellular interaction --- Intercellular communication --- Cellular control mechanisms --- Signal Transduction. --- Biological Evolution. --- Cell Differentiation. --- Origin of Life. --- Genesis of Life --- Life Geneses --- Life Genesis --- Life Origin --- Life Origins --- Organelle Biogenesis --- Prebiotic Chemical Evolution --- Chemical Evolution, Prebiotic --- Evolution, Prebiotic Chemical --- Prebiotic Chemical Evolutions --- Evolution.


Book
Plant Signal Transduction : Methods and Protocols
Author:
ISBN: 1588299430 9781588299437 9781597452892 1597452890 Year: 2009 Publisher: Totowa, NJ : Humana Press : Imprint: Humana,

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Abstract

During recent years, research has greatly expanded our understanding of the sophisticated molecular network of responses which enable plants to develop, survive and propagate under a wide range of conditions. In Plant Signal Transduction: Methods and Protocols, an international panel of experts provide well-established methods vital to analyzing plant signal transduction on the molecular level. Featuring experimental procedures on several of the most popular model organisms, the volume focuses on in planta analyses and the proteins involved in signal transduction in order to aid with the establishment of laboratory techniques or the modification of the protocols for other plants. As part of the highly successful Methods in Molecular Biology™ series, the chapters include brief introductions to the subject, lists of necessary materials, readily reproducible laboratory protocols, and tips on trouble-shooting and avoiding known pitfalls. Comprehensive and cutting-edge, Plant Signal Transduction: Methods and Protocols will benefit plant scientists wishing to improve their experimental approaches and delve further into this exciting and important field of study.

Keywords

Plant cellular signal transduction --- Plant molecular biology --- Growth and Development --- Signal Transduction --- Gene Expression Regulation, Plant --- Plant Physiological Phenomena --- Plants --- Gene Expression Regulation --- Physiological Processes --- Cell Physiological Processes --- Biochemical Processes --- Phenomena and Processes --- Eukaryota --- Chemical Processes --- Genetic Processes --- Physiological Phenomena --- Organisms --- Cell Physiological Phenomena --- Biochemical Phenomena --- Chemical Phenomena --- Genetic Phenomena --- Plant Physiology --- Botany --- Earth & Environmental Sciences --- Plant cellular signal transduction. --- Plant molecular biology. --- Transduction du signal cellulaire chez les plantes. --- Transduction du signal. --- Gene Expression Regulation, Plant. --- Plant Physiological Phenomena. --- Signal Transduction. --- growth & development. --- Genetic Concepts --- Genetic Phenomenon --- Genetic Process --- Concept, Genetic --- Concepts, Genetic --- Genetic Concept --- Phenomena, Genetic --- Phenomenon, Genetic --- Process, Genetic --- Processes, Genetic --- Chemical Phenomenon --- Chemical Process --- Physical Chemistry Phenomena --- Physical Chemistry Process --- Physicochemical Phenomenon --- Physicochemical Process --- Chemical Concepts --- Physical Chemistry Concepts --- Physical Chemistry Processes --- Physicochemical Concepts --- Physicochemical Phenomena --- Physicochemical Processes --- Chemical Concept --- Chemistry Process, Physical --- Chemistry Processes, Physical --- Concept, Chemical --- Concept, Physical Chemistry --- Concept, Physicochemical --- Concepts, Chemical --- Concepts, Physical Chemistry --- Concepts, Physicochemical --- Phenomena, Chemical --- Phenomena, Physical Chemistry --- Phenomena, Physicochemical --- Phenomenon, Chemical --- Phenomenon, Physicochemical --- Physical Chemistry Concept --- Physicochemical Concept --- Process, Chemical --- Process, Physical Chemistry --- Process, Physicochemical --- Processes, Chemical --- Processes, Physical Chemistry --- Processes, Physicochemical --- Biochemical Concepts --- Biochemical Phenomenon --- Biochemical Process --- Phenomena, Biochemical --- Biochemical Concept --- Concept, Biochemical --- Concepts, Biochemical --- Phenomenon, Biochemical --- Process, Biochemical --- Processes, Biochemical --- Cell Physiological Phenomenon --- Cell Physiological Process --- Physiology, Cell --- Cell Physiology --- Phenomena, Cell Physiological --- Phenomenon, Cell Physiological --- Physiological Process, Cell --- Physiological Processes, Cell --- Process, Cell Physiological --- Processes, Cell Physiological --- Cells --- Physiological Concepts --- Physiological Phenomenon --- Physiological Process --- Concept, Physiological --- Concepts, Physiological --- Phenomena, Physiological --- Phenomenas, Physiological --- Phenomenon, Physiological --- Physiological Concept --- Process, Physiological --- Processes, Physiological --- Eucarya --- Eukarya --- Eukaryotes --- Eukaryotas --- Eukaryote --- Expression Regulation, Gene --- Regulation, Gene Action --- Regulation, Gene Expression --- Gene Action Regulation --- Regulation of Gene Expression --- Plant --- Physiology, Plant --- Plant Physiologic Phenomena --- Plant Physiologic Phenomenon --- Plant Physiological Phenomenon --- Plant Physiological Process --- Plant Physiological Processes --- Phenomena, Plant Physiologic --- Phenomena, Plant Physiological --- Phenomenon, Plant Physiologic --- Phenomenon, Plant Physiological --- Phenomenons, Plant Physiological --- Physiologic Phenomena, Plant --- Physiologic Phenomenon, Plant --- Physiological Phenomena, Plant --- Physiological Phenomenon, Plant --- Physiological Phenomenons, Plant --- Physiological Process, Plant --- Physiological Processes, Plant --- Plant Physiological Phenomenons --- Process, Plant Physiological --- Processes, Plant Physiological --- Regulation, Gene Expression, Plant --- Plant Gene Expression Regulation --- Regulation of Gene Expression, Plant --- Receptor Mediated Signal Transduction --- Signal Transduction Pathways --- Signal Transduction Systems --- Receptor-Mediated Signal Transduction --- Signal Pathways --- Pathway, Signal --- Pathway, Signal Transduction --- Pathways, Signal --- Pathways, Signal Transduction --- Receptor-Mediated Signal Transductions --- Signal Pathway --- Signal Transduction Pathway --- Signal Transduction System --- Signal Transduction, Receptor-Mediated --- Signal Transductions --- Signal Transductions, Receptor-Mediated --- System, Signal Transduction --- Systems, Signal Transduction --- Transduction, Signal --- Transductions, Signal --- Development and Growth --- Molecular phytobiology --- Phytobiology, Molecular --- physiology --- Life sciences. --- Plant biochemistry. --- Plant science. --- Botany. --- Plant physiology. --- Life Sciences. --- Plant Physiology. --- Plant Sciences. --- Plant Biochemistry. --- Physiology --- Botanical science --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Biology --- Natural history --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Phytochemicals --- Plant biochemical genetics --- Biosciences --- Sciences, Life --- Science --- Biochemistry. --- Biological chemistry --- Chemical composition of organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Composition --- Floristic botany --- Fisiologia vegetal --- Transducció de senyal cel·lular --- Fitoquímica --- Manuals de laboratori --- Tècniques de laboratori --- Bioquímica de les plantes --- Bioquímica vegetal --- Botànica química --- Química botànica --- Química de les plantes --- Química vegetal --- Bioquímica --- Hormones vegetals --- Pigments vegetals --- Proteïnes vegetals --- Biologia molecular vegetal --- Transducció de la informació cel·lular --- Regulació cel·lular --- Missatgers secundaris (Bioquímica) --- Botànica --- Absorció de l'aigua en les plantes --- Assimilació de les plantes --- Creixement (Plantes) --- Ecofisiologia vegetal --- Fecundació de les plantes --- Fisiologia postcollita --- Ritmes biològics en les plantes --- Floració --- Germinació --- Metabolisme de les plantes --- Moviments de les plantes --- Nutrició vegetal --- Reproducció de les plantes --- Respiració de les plantes --- Saprofitisme --- Tropisme

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