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Apoptosis: Involvement of Oxidative Stress and Intracellular Ca2+ Homeostasis, presents a concise synthesis of the current knowledge and recent advances in the mechanisms of apoptosis in different cells and the role of oxidative stress and Ca2+ signalling. Particular attention is given to the different features of apoptosis in distinct cell types, ranging from hepatocytes to cardiovascular and blood cells, nervous cells or spermatozoa. Cutting-edge and user-friendly, this volume serves as a comprehensive resource for those interested in the fascinating biological processes associated to programmed cell death or apoptosis. The book is divided in two major chapter sections: general mechanisms of the apoptotic pathways and the role of oxidative stress and intracellular Ca2+ homeostasis and a more specific section dedicated to the specificities of apoptosis in a number of excitable and non-excitable cells. All of the contributions are from specialists in the field and the reviews presented, systemically examine the most exciting and innovative aspects of the apoptotic pathways in their particular areas of expertise.

Apoptosis. --- Cellular signal transduction. --- Homeostasis. --- Intracellular calcium. --- Oxidative stress. --- Apoptosis --- Oxidative stress --- Intracellular calcium --- Cellular signal transduction --- Homeostasis --- Cell Death --- Second Messenger Systems --- Ion Transport --- Physiological Processes --- Stress, Physiological --- Metabolism --- Metabolic Phenomena --- Cell Physiological Processes --- Biological Transport --- Physiological Phenomena --- Signal Transduction --- Phenomena and Processes --- Biochemical Processes --- Cell Physiological Phenomena --- Biochemical Phenomena --- Chemical Processes --- Chemical Phenomena --- Oxidative Stress --- Calcium Signaling --- Biology --- Health & Biological Sciences --- Cytology --- Cell metabolism. --- Cells --- Medicine. --- Cancer research. --- Oncology. --- Cell biology. --- Cell physiology. --- Biomedicine. --- Cancer Research. --- Cell Biology. --- Cell Physiology. --- Cell death --- Cellular control mechanisms --- Oncology  . --- Cytology. --- Cell function --- Physiology --- Cell biology --- Cellular biology --- Cytologists --- Tumors --- Cancer research

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Recent experimental research advances have led to increasingly detailed descriptions of how networks of interacting neurons process information. With these developments, it has become clear that dynamic network behaviors underlie information processing, and that the observed activity patterns cannot be fully explained by simple concepts such as synchrony and phase locking. These new insights raise significant challenges and offer exciting opportunities for experimental and theoretical neuroscientists. Coherent Behavior in Neuronal Networks features a review of recent research in this area from some of the world’s foremost experts on systems neuroscience. The book presents novel methodologies and interdisciplinary perspectives, and will serve as an invaluable resource to the research community. Highlights include the results of interdisciplinary collaborations and approaches as well as topics, such as the interplay of intrinsic and synaptic dynamics in producing coherent neuronal network activity and the roles of globally coherent rhythms and oscillations in the coordination of distributed processing, that are of significant research interest but have been underrepresented in the review literature. With its cutting-edge mathematical, statistical, and computational techniques, this volume will be of interest to all researchers and students in the field of systems neuroscience. About the Editors: Krešimir Josic works in different areas of mathematical biology and applied dynamics, with a particular interest in understanding how information is represented in neuronal networks. He is an associate professor at the University of Houston and a member of the steering committees of the Gulf Coast Consortium for Theoretical and Computational Neuroscience, and the Center for the Mathematical Biosciences in Houston. Jonathan Rubin is a Professor of Mathematics at the University of Pittsburgh, with research interests in nonlinear dynamics and mathematical biology, particularly neuroscience. He is affiliated with the Center for Neuroscience at University of Pittsburgh, the Pitt/Carnegie Mellon University Center for the Neural Basis of Cognition and Computational Biology program, and the McGowan Institute for Regenerative Medicine. Manuel Matías is a Senior Faculty Research Scientist of the Spanish National Research Council (CSIC) working at the Institute for Cross-Disciplinary Physics and Complex Systems (IFISC) in Palma de Mallorca, Spain. Ranulfo Romo is Professor of Neuroscience at the Instituto de Fisiología Celular-Neurociencias, National Autonomous University of Mexico (UNAM). He is a member of the Neurosciencies Research Program, and a foreign associate of the U.S. National Academy of Sciences.

Computational neuroscience. --- Neurosciences. --- Neurosciences --- Computational neuroscience --- Nervous System --- Feedback --- Cells --- Homeostasis --- Nervous System Physiological Processes --- Models, Biological --- Anatomy --- Models, Theoretical --- Physiological Processes --- Cybernetics --- Nervous System Physiological Phenomena --- Physiological Phenomena --- Musculoskeletal and Neural Physiological Phenomena --- Investigative Techniques --- Communication --- Phenomena and Processes --- Information Science --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Feedback, Physiological --- Neuronal Plasticity --- Nerve Net --- Neurons --- Models, Neurological --- Human Anatomy & Physiology --- Health & Biological Sciences --- Neuroscience --- Neural networks (Neurobiology) --- Cognitive neuroscience. --- Cognitive neuropsychology --- Biological neural networks --- Nets, Neural (Neurobiology) --- Networks, Neural (Neurobiology) --- Neural nets (Neurobiology) --- Medicine. --- Neurology. --- Bioinformatics. --- Computational biology. --- Neurobiology. --- Biomedicine. --- Computer Appl. in Life Sciences. --- Cognitive neuroscience --- Neurobiology --- Neural circuitry --- Cognitive science --- Neuropsychology --- Biology --- Data processing. --- Medicine --- Nervous system --- Neuropsychiatry --- Neural sciences --- Neurological sciences --- Medical sciences --- Diseases --- Neurology . --- Bioinformatics . --- Computational biology . --- Bioinformatics --- Bio-informatics --- Biological informatics --- Information science --- Computational biology --- Systems biology --- Data processing