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Breast Cancer is the most common tumor in women and it is the second leading cause of cancer deaths worldwide. Due to breakthroughs in gene profiling, the knowledge of the pathophysiology of the mammary gland had greatly increased over the last decade. In Breast Cancer in the Post Genomic Era, Antonio Giordano, Nicola Normanno, and a panel of international authorities in their field provide a comprehensive approach to the biology, diagnosis, prevention, and treatment of human breast carcinoma. The book provides a comprehensive approach to breast cancer, describing the use of gene profiling techniques to distinguish specific features of individual carcinomas, as well as emerging novel therapeutic approaches to treatment. Additional chapters cover the use of transgenic mice to model human breast cancer and the role of the EGF-CFC family in mammary gland development and neoplasia. Breast Cancer in the Post Genomic-Era succeeds in looking at breast cancer pathogenesis, diagnosis, and treatment under a more comprehensive light, and is a valuable resource for any Radiation or Surgical Oncologist, Cancer Biologist or Pathologist.
Breast -- Cancer -- Diagnosis. --- Breast -- Cancer -- Etiology. --- Breast -- Cancer -- Genetic aspects. --- Breast -- Cancer -- Treatment. --- Breast --- Breast Diseases --- Neoplasms by Site --- Neoplasms --- Skin Diseases --- Skin and Connective Tissue Diseases --- Diseases --- Breast Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Cancer --- Etiology --- Diagnosis --- Treatment --- Genetic aspects --- Diagnosis. --- Etiology. --- Genetic aspects. --- Treatment. --- Medicine. --- Oncology. --- Pathology. --- Surgical oncology. --- Medicine & Public Health. --- Surgical Oncology. --- Oncology . --- Disease (Pathology) --- Medical sciences --- Medicine, Preventive --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Tumors --- Excision
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Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable. "The adjuvant treatment of breast cancer has become standard of care. A spectrum of biologic and prognostic factors are considered before a therapeutic strategy is implemented. In this text leading investigators in the field discuss current management and critical investigative issues." Steven T. Rosen, M.D. Series Editor.
Breast -- Cancer -- Adjuvant treatment. --- Breast -- Cancer -- Treatment. --- Breast -- Cancer. --- Cancer. --- Breast --- Breast Diseases --- Combined Modality Therapy --- Radiotherapy --- Neoplasms by Site --- Pharmaceutic Aids --- Drug Therapy --- Therapeutics --- Neoplasms --- Skin Diseases --- Specialty Uses of Chemicals --- Pharmaceutical Preparations --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Diseases --- Skin and Connective Tissue Diseases --- Chemical Actions and Uses --- Chemicals and Drugs --- Adjuvants, Pharmaceutic --- Chemotherapy, Adjuvant --- Radiotherapy, Adjuvant --- Breast Neoplasms --- Medicine --- Health & Biological Sciences --- Oncology --- Adjuvant treatment --- Cancer --- Adjuvant treatment. --- Treatment. --- Medicine. --- Cancer research. --- Oncology. --- Surgical oncology. --- Medicine & Public Health. --- Surgical Oncology. --- Cancer Research. --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Tumors --- Cancer research --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Excision --- Treatment
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Breast --- Sein --- Cancer --- Periodicals --- Treatment --- Périodiques --- Traitement --- Breast Neoplasms. --- Cancer. --- Breast Cancer. --- Breast Carcinoma --- Cancer of the Breast --- Human Mammary Carcinoma --- Malignant Neoplasm of Breast --- Malignant Tumor of Breast --- Mammary Cancer --- Mammary Carcinoma, Human --- Mammary Neoplasm, Human --- Mammary Neoplasms, Human --- Neoplasms, Breast --- Tumors, Breast --- Breast Cancer --- Breast Tumors --- Cancer of Breast --- Breast Carcinomas --- Breast Malignant Neoplasm --- Breast Malignant Neoplasms --- Breast Malignant Tumor --- Breast Malignant Tumors --- Breast Neoplasm --- Breast Tumor --- Cancer, Breast --- Cancer, Mammary --- Cancers, Mammary --- Carcinoma, Breast --- Carcinoma, Human Mammary --- Carcinomas, Breast --- Carcinomas, Human Mammary --- Human Mammary Carcinomas --- Human Mammary Neoplasm --- Human Mammary Neoplasms --- Mammary Cancers --- Mammary Carcinomas, Human --- Neoplasm, Breast --- Neoplasm, Human Mammary --- Neoplasms, Human Mammary --- Tumor, Breast --- Breasts --- breast cancer --- anticancer agents --- screening --- therapy --- palliative care --- Breast Cancer Lymphedema --- Chest --- Large-breasted women --- cancer screening --- Oncology. Neoplasms
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Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.
Breast -- Cancer -- Radiotherapy. --- Breast -- Cancer -- Treatment. --- Breast --- Radiotherapy, Conformal --- Breast Neoplasms --- Radiotherapy, Computer-Assisted --- Neoplasms by Site --- Breast Diseases --- Therapy, Computer-Assisted --- Neoplasms --- Radiotherapy --- Skin Diseases --- Decision Making, Computer-Assisted --- Diseases --- Skin and Connective Tissue Diseases --- Therapeutics --- Medical Informatics Applications --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medical Informatics --- Information Science --- Radiology, MRI, Ultrasonography & Medical Physics --- Oncology --- Medicine --- Health & Biological Sciences --- Cancer --- Radiotherapy. --- Medicine. --- Radiology. --- Oncology. --- Medicine & Public Health. --- Diagnostic Radiology. --- Treatment --- Oncology . --- Radiology, Medical. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Tumors --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Medical radiology --- Therapeutics, Physiological --- Phototherapy --- Radiological services --- Radiological physics --- Physics --- Radiation
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Sociology of culture --- Zoology --- Human physiology --- Oncology. Neoplasms --- Human medicine --- Engineering sciences. Technology --- Artificial intelligence. Robotics. Simulation. Graphics --- Art --- Film --- Theatrical science --- Fiction --- Essays --- Movies --- Body --- Literature --- Medical sciences --- Popular culture --- Dying --- Comic strips --- Technology --- Theatre --- Theory --- Appearance --- Book --- Breast cancer --- Cyborgs --- Animals --- Imaging
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Although there is broad agreement that the way that health care providers are paid affects their performance, the empirical literature on the impacts of provider payment reforms is surprisingly thin. During the 1990s and early 2000s, many European and Central Asian countries shifted from paying hospitals through historical budgets to fee-for-service or patient-based-payment methods (mostly variants of diagnosis-related groups). Using panel data on 28 countries over the period 1990-2004, the authors of this study exploit the phased shift from historical budgets to explore aggregate impacts on hospital throughput, national health spending, and mortality from causes amenable to medical care. They use a regression version of difference-in-differences and two variants that relax the difference-in-differences parallel trends assumption. The results show that fee-for-service and patient-based-payment methods both increased national health spending, including private (out-of-pocket) spending. However, they had different effects on inpatient admissions (fee-for-service increased them; patient-based-payment had no effect), and average length of stay (fee-for-service had no effect; patient-based-payment reduced it). Of the two methods, only patient-based-payment appears to have had any beneficial effect on "amenable mortality," but there were significant impacts for only a couple of causes of death, and not in all model specifications.
Aged --- Breast cancer --- Death rate --- Diabetes --- Digestive system --- Exercises --- Health care --- Health Economics and Finance --- Health for all --- Health Monitoring and Evaluation --- Health outcomes --- Health Systems Development and Reform --- Health, Nutrition and Population --- Hospital admission --- Hospitalization --- Hospitals --- Mortality --- Patient --- Patients --- Physicians --- Primary health care --- Public health --- Quality of life --- Screening
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During the Vietnam War, more than 70 million liters of military herbicide were sprayed over the combat zone. This study uses self and proxy-reported data on cancer status obtained from a nationally representative health survey of the Vietnamese population (N=158,019), combined with measures of military herbicide exposure computed from detailed information on US and allied wartime military activities. No significant difference in the prevalence of reported cancer is detected between communes with some degree of exposure and those with none. When restricting the analysis to exposed communes and adopting a continuous measure of herbicide exposure, there is evidence of a dose-response relationship; among communes that were exposed, increasing exposure to past military spraying is associated with increasing prevalence of reported cancer in 2001-2002. There is mixed evidence as to whether cohorts born before or after the end of the spraying campaigns are equally affected.
Alcohol consumption --- Breast cancer --- Brown Issues and Health --- Conflict and Development --- Disease Control and Prevention --- Environment --- Epidemiology --- Epilepsy --- Gender --- Gender and Health --- Hazard Risk Management --- Health care --- Health effects --- Health Monitoring and Evaluation --- Health outcomes --- Health, Nutrition and Population --- Leukemia --- Mental health --- Migration --- Morbidity --- Mortality --- Outpatient care --- Peace and Peacekeeping --- Pollution --- Population Policies --- Prostate cancer --- Risk factors --- Screening --- Smoking --- Urban Development --- Victims --- Violence
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During the Vietnam War, more than 70 million liters of military herbicide were sprayed over the combat zone. This study uses self and proxy-reported data on cancer status obtained from a nationally representative health survey of the Vietnamese population (N=158,019), combined with measures of military herbicide exposure computed from detailed information on US and allied wartime military activities. No significant difference in the prevalence of reported cancer is detected between communes with some degree of exposure and those with none. When restricting the analysis to exposed communes and adopting a continuous measure of herbicide exposure, there is evidence of a dose-response relationship; among communes that were exposed, increasing exposure to past military spraying is associated with increasing prevalence of reported cancer in 2001-2002. There is mixed evidence as to whether cohorts born before or after the end of the spraying campaigns are equally affected.
Alcohol consumption --- Breast cancer --- Brown Issues and Health --- Conflict and Development --- Disease Control and Prevention --- Environment --- Epidemiology --- Epilepsy --- Gender --- Gender and Health --- Hazard Risk Management --- Health care --- Health effects --- Health Monitoring and Evaluation --- Health outcomes --- Health, Nutrition and Population --- Leukemia --- Mental health --- Migration --- Morbidity --- Mortality --- Outpatient care --- Peace and Peacekeeping --- Pollution --- Population Policies --- Prostate cancer --- Risk factors --- Screening --- Smoking --- Urban Development --- Victims --- Violence
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Although there is broad agreement that the way that health care providers are paid affects their performance, the empirical literature on the impacts of provider payment reforms is surprisingly thin. During the 1990s and early 2000s, many European and Central Asian countries shifted from paying hospitals through historical budgets to fee-for-service or patient-based-payment methods (mostly variants of diagnosis-related groups). Using panel data on 28 countries over the period 1990-2004, the authors of this study exploit the phased shift from historical budgets to explore aggregate impacts on hospital throughput, national health spending, and mortality from causes amenable to medical care. They use a regression version of difference-in-differences and two variants that relax the difference-in-differences parallel trends assumption. The results show that fee-for-service and patient-based-payment methods both increased national health spending, including private (out-of-pocket) spending. However, they had different effects on inpatient admissions (fee-for-service increased them; patient-based-payment had no effect), and average length of stay (fee-for-service had no effect; patient-based-payment reduced it). Of the two methods, only patient-based-payment appears to have had any beneficial effect on "amenable mortality," but there were significant impacts for only a couple of causes of death, and not in all model specifications.
Aged --- Breast cancer --- Death rate --- Diabetes --- Digestive system --- Exercises --- Health care --- Health Economics and Finance --- Health for all --- Health Monitoring and Evaluation --- Health outcomes --- Health Systems Development and Reform --- Health, Nutrition and Population --- Hospital admission --- Hospitalization --- Hospitals --- Mortality --- Patient --- Patients --- Physicians --- Primary health care --- Public health --- Quality of life --- Screening
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Breast --- Breast Neoplasms. --- Cancer --- Cancer. --- Breast Carcinoma --- Cancer of the Breast --- Human Mammary Carcinoma --- Malignant Neoplasm of Breast --- Malignant Tumor of Breast --- Mammary Cancer --- Mammary Carcinoma, Human --- Mammary Neoplasm, Human --- Mammary Neoplasms, Human --- Neoplasms, Breast --- Tumors, Breast --- Breast Cancer --- Breast Tumors --- Cancer of Breast --- Breast Carcinomas --- Breast Malignant Neoplasm --- Breast Malignant Neoplasms --- Breast Malignant Tumor --- Breast Malignant Tumors --- Breast Neoplasm --- Breast Tumor --- Cancer, Breast --- Cancer, Mammary --- Cancers, Mammary --- Carcinoma, Breast --- Carcinoma, Human Mammary --- Carcinomas, Breast --- Carcinomas, Human Mammary --- Human Mammary Carcinomas --- Human Mammary Neoplasm --- Human Mammary Neoplasms --- Mammary Cancers --- Mammary Carcinomas, Human --- Neoplasm, Breast --- Neoplasm, Human Mammary --- Neoplasms, Human Mammary --- Tumor, Breast --- Breasts --- Breast Cancer Lymphedema --- Chest --- Large-breasted women --- Oncology --- Health Sciences --- Clinical Medicine --- Càncer de mama --- Oncologia --- Càncer de mama. --- Oncologia.
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