Narrow your search
Listing 1 - 8 of 8
Sort by

Book
Hyaluronan in cancer biology
Author:
ISBN: 9780123741783 0123741785 9780080921082 0080921086 1282168576 9781282168572 9786612168574 6612168579 Year: 2009 Publisher: San Diego, Calif. : Academic Press,

Loading...
Export citation

Choose an application

Bookmark

Abstract

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered


Digital
Hyaluronan in cancer biology
Author:
ISBN: 9780123741783 0123741785 9780080921082 0080921086 1282168576 9781282168572 9786612168574 6612168579 Year: 2009 Publisher: San Diego, CA Academic Press/Elsevier

Loading...
Export citation

Choose an application

Bookmark

Abstract

Hyaluronan biology is being recognized as an important regulator of cancer progression. Paradoxically, both hyaluronan (HA) and hyaluronidases, the enzymes that eliminate HA, have also been correlated with cancer progression. Hyaluronan, a long-chain polymer of the extracellular matrix, opens up tissue spaces through which cancer cells move and metastasize. It also confers motility upon cells through interactions of cell-surface HA with the cytoskeleton. Embryonic cells in the process of movement and proliferation use the same strategy. It is an example of how cancer cells have commandeered normal cellular processes for their own survival and spread. There are also parallels between cancer and wound healing, cancer occasionally being defined as a wound that does not heal. The growing body of literature regarding this topic has recently progressed from describing the association of hyaluronan and hyaluronidase expression associated with different cancers, to understanding the mechanisms that drive tumor cell activation, proliferation, drug resistance, etc. No one source, however, discusses hyaluronan synthesis and catabolism, as well as the factors that regulate the balance. This book offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer. Offers a comprehensive summary and cutting-edge insight into Hyaluronan biology, the role of the HA receptors, the hyaluronidase enzymes that degrade HA, as well as HA synthesis enzymes and their relationship to cancer. Chapters are written by the leading international authorities on this subject, from laboratories that focus on the investigation of hyaluronan in cancer initiation, progression, and dissemination.

Keywords


Book
Globalization and international trade policies
Author:
ISBN: 9812700137 9786612760259 1282760254 9812798099 9789812798091 9789812700131 Year: 2009 Publisher: Hackensack, New Jersey : World Scientific,

Loading...
Export citation

Choose an application

Bookmark

Abstract

This book brings together a collection of papers that Robert M Stern and his co-authors have written in recent years. The collection addresses a variety of issues pertinent to the global trading system. One group of papers deals with globalization in terms of what the public needs to know about this phenomenon and the role of the World Trade Organization (WTO), whether some countries may be hurt by globalization, how global market integration relates to national sovereignty, and how and whether considerations of fairness are and should be dealt with in the global trading system and WTO negotiation


Book
Architecture on the edge of postmodernism : collected essays, 1964-1988
Authors: ---
ISBN: 9780300153972 Year: 2009 Publisher: New Haven : Yale University Press,

Loading...
Export citation

Choose an application

Bookmark

Abstract


Periodical
European journal of philosophy books series
Authors: --- ---
Year: 2009 Publisher: Oxford Wiley-Blackwell

Loading...
Export citation

Choose an application

Bookmark

Abstract

Keywords


Book
New York 1930 : architecture between the two World Wars.
Authors: --- ---
ISBN: 9780847830961 Year: 2009 Publisher: New York Rizzoli

Loading...
Export citation

Choose an application

Bookmark

Abstract

Listing 1 - 8 of 8
Sort by