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2008 (2)

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Toll-like receptors (TLRs) and innate immunity
Authors: --- ---
ISBN: 1281138096 9786611138097 3540721673 3540721665 Year: 2008 Volume: 183 Publisher: Berlin : Springer,

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Abstract

Overall recent research on TLRs has led to tremendous increase in our understanding of early steps in pathogen recognition and will presumably lead to potent TLR targeting therapeutics in the future. This book reviews and highlights our recent understanding on the function and ligands of TLRs as well as their role in autoimmunity, dendritic cell activation and target structures for therapeutic intervention.


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Multichain immune recognition receptor signaling : from spatiotemporal organization to human disease
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ISBN: 1281953849 9786611953843 0387097899 0387097880 1441918876 Year: 2008 Publisher: New York, N.Y. : Austin, Tex. : Springer Science+Business Media ; Landes Bioscience,

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Abstract

Shows that the structural similarity of the Multichain Immune Recognition Receptors (MIRRs) determines the general principles underlying MIRR-mediated transmembrane signaling mechanisms. This book provides the basis for existing and future therapeutic strategies targeting MIRRs.

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