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This textbook will be an invaluable resource whether you are a gastroenterologist, internist, surgeon, or other clinician who sees patients with gastrointestinal and liver disorders. It should be kept close at hand for frequent consultation.

Gastrointestinal Diseases --- Gastroenterology. --- Gastroenterology --- Gastrointestinal system --- Liver --- Liver Diseases --- Diseases --- Gastrointestinal Diseases. --- Liver diseases. --- Diseases. --- Gastrointestinal system - Diseases --- Liver - Diseases

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Biliary tract --- Liver --- Pediatric gastroenterology --- Child --- Infant --- Liver Diseases --- Diseases --- Diseases

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Over the past 2 decades, there has been a steady increase in knowledge associated with the clinical manifestations of cholestatic liver disease. In addition to a growing amount of information on the well-studied disorders of primary biliary cirrhosis and primary sclerosing cholangitis, there has been a rapid accumulation of data on less well-known but important topics such as overlap syndromes with autoimmune hepatitis, cholestatic variants of alcohol and viral disease, and cholestasis following liver transplantation. These emerging insights are complemented by further improvements of the diagnosis and management of cholestasis. Based on these clinical situations, Cholestatic Liver Disease provides essential information for individuals involved in the care of patients affected by cholestatic liver disease. This groundbreaking text also supplies scientific updates from leading experts which relate to the clinical evaluation and management of cholestatic liver disorders, useful for both novice and practitioners alike. Among the topics discussed in this volume are PBC, PSC, overlap syndrome with autoimmune hepatits, sarcoid, lymphoma, cystic fibrosis, rheumatologic disease, and osteoporosis. Comprehensive and timely, Cholestatic Liver Disease is sure to be an indispensable reference for all those who work with cholestatic liver.

Medicine & Public Health. --- Gastroenterology. --- Internal Medicine. --- Surgery. --- General Practice / Family Medicine. --- Medicine. --- Family medicine. --- Internal medicine. --- Médecine --- Médecine familiale --- Médecine interne --- Gastroentérologie --- Chirurgie --- Cholestasis, Intrahepatic. --- Cholestasis. --- Liver -- Diseases. --- Liver --- Cholestasis --- Cholestasis, Intrahepatic --- Liver Diseases --- Bile Duct Diseases --- Digestive System Diseases --- Diseases --- Biliary Tract Diseases --- Gastroenterology --- Medicine --- Health & Biological Sciences --- Diseases. --- Biliary stasis --- Stasis, Biliary --- General practice (Medicine). --- Surgery, Primitive --- Internal medicine --- Digestive organs --- Medicine, Internal --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Jaundice, Obstructive

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This book provides an in-depth account of all aspects of radioembolization, a relatively novel technique based on the efficacy of radiotherapy for the treatment of liver tumors. In the past, the therapeutic radiation dose needed to treat a tumoral area has been sufficiently high to produce permanent damage to the nontumoral liver parenchyma. Radioembolization attempts to overcome this problem by combining embolization (intravascular deployment of particles) and brachytherapy (local administration of radiotherapy with the aid of a device, namely the particles themselves). The technique is based on improvements in percutaneous endovascular procedures which have allowed the deployment of small (25-35 µm) microspheres loaded with yttrium-90 that deliver high doses of beta-radiation specifically to the tumoral area. Performance of the procedure demands close familiarity with the hepatic vascular anatomy in order to ensure avoidance of vessels going to other territories. Furthermore, detailed knowledge of liver function, tumor volume, and liver vascular shunting is needed in order to calculate the appropriate therapeutic dose in each particular case. All of these topics are addressed in depth in this book, and initial clinical results are presented, showing that constant local control can be achieved with a reasonably low rate of complications. These promising results may lead to a progressive change in the therapeutic indication for radioembolization, and in some cases it could even become the therapy of choice.

Medicine & Public Health. --- Imaging / Radiology. --- Interventional Radiology. --- Nuclear Medicine. --- Hepatology. --- Oncology. --- Radiotherapy. --- Medicine. --- Medical radiology --- Interventional radiology. --- Nuclear medicine. --- Clinical medicine. --- Médecine --- Radiologie médicale --- Radiologie interventionnelle --- Médecine nucléaire --- Radiothérapie --- Médecine clinique --- Cancérologie --- Brachytherapy -- Methods. --- Embolization, Therapeutic -- Methods. --- Liver -- Cancer -- Treatment. --- Liver Neoplasms -- Radiotherapy. --- Radioisotope brachytherapy. --- Therapeutic embolization. --- Brachytherapy --- Liver Neoplasms --- Embolization, Therapeutic --- Digestive System Neoplasms --- Radiotherapy --- Hemostatic Techniques --- Liver Diseases --- Digestive System Diseases --- Neoplasms by Site --- Therapeutics --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Neoplasms --- Radiology, MRI, Ultrasonography & Medical Physics --- Oncology --- Medicine --- Health & Biological Sciences --- Liver --- Cancer --- Treatment. --- Embolotherapy --- Afterloading radiotherapy --- Brachyisotope therapy --- Brachytherapy, Radioisotope --- Implant radiotherapy --- Interstitial radiotherapy --- Radiology. --- Hemostasis, Surgical --- Interventional radiology --- Implants, Artificial --- Radioisotopes --- Therapeutic use --- Radiology, Medical. --- Oncology  . --- Radiation therapy --- Electrotherapeutics --- Hospitals --- Medical electronics --- Therapeutics, Physiological --- Phototherapy --- Tumors --- Medicine, Clinical --- Atomic medicine --- Radioisotopes in medicine --- Radioactive tracers --- Radioactivity --- Radiology, Interventional --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Radiological services --- Physiological effect --- Interventional radiology . --- Gastroenterology --- Radiological physics --- Physics --- Radiation