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This comprehensive volume, written by experts in the field, emphasizes the most recent advances on the Hepatitis C virus infection (HCV) moving from basic research to clinical application. In spite of the numerous studies on HCV infection, its pathogenesis and medical treatment have not been fully explained. The first chapters of this volume analyize the full spectrum of immune responses to HCV taking into account either innate or adoptive immunity involvement. The volume also includes a series of contributions which explain the state of art of IFN-alpha treatment in HCV patients and the effectiveness of therapy also in relation to HCV genotypes. The use and applications of pegylated IFNs will also be discussed as well as the complicated HCV disease and its treatment. Hepatitis C Virus Disease: Immunobiology and Clinical Applications is an ideal volume for researchers, scientists, professionals, clinicians, physicians and graduate students in the fields of infectious disease, immunology, virology, microbiology, pharmacology and medicine.

Hepatitis C --- Interferon --- Treatment. --- Therapeutic use. --- Medicine. --- Immunology. --- Virology. --- Biomedicine. --- Microbiology --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Hepatitis, Non-A, non-B --- Non-A, non-B hepatitis, Parenterally-transmitted --- Parenterally-transmitted non-A, non-B hepatitis --- Flaviviral diseases --- Hepatitis, Viral --- Medical virology. --- Medical microbiology --- Virology --- Virus diseases

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The Agreement on Trade Related Aspects of Intellectual Property rights (TRIPS) requires all WTO members to adopt certain minimum standards for the protection of intellectual property rights including the rights of holders of patents for pharmaceutical products. The adoption of the standards delineated by the TRIPS Agreement appears to have resulted in significant loss of public health policy flexibilities for developing country members with respect to regulating the grant and use of pharmaceutical patents and controlling the cost of medicines. The Agreement, however, provides inherent flexibil

Antiretroviral agents. --- Antiretroviral agents --- Delivery of Health Care --- Anti-Retroviral Agents --- Africa --- Intellectual Property --- Industry --- Patient Care Management --- Geographic Locations --- Antiviral Agents --- Technology, Industry, and Agriculture --- Jurisprudence --- Health Care Quality, Access, and Evaluation --- Geographicals --- Social Control, Formal --- Health Services Administration --- Technology, Industry, Agriculture --- Health Care --- Anti-Infective Agents --- Therapeutic Uses --- Health Care Economics and Organizations --- Sociology --- Pharmacologic Actions --- Social Sciences --- Chemical Actions and Uses --- Anthropology, Education, Sociology and Social Phenomena --- Chemicals and Drugs --- Africa South of the Sahara --- Health Services Accessibility --- Drug Industry --- Anti-HIV Agents --- Patents as Topic --- Medicine --- Health & Biological Sciences --- Clinical Immunology --- Trademarks --- Patents as Topics --- Trademark --- Anti-AIDS Drugs --- Anti-HIV Drugs --- AIDS Drugs --- Anti-AIDS Agents --- Agents, Anti-AIDS --- Agents, Anti-HIV --- Anti AIDS Agents --- Anti AIDS Drugs --- Anti HIV Agents --- Anti HIV Drugs --- Drugs, AIDS --- Drugs, Anti-AIDS --- Drugs, Anti-HIV --- Industries, Pharmaceutic --- Industry, Drug --- Industry, Pharmaceutic --- Industry, Pharmaceutical --- Pharmaceutical Industry --- Drug Industries --- Industries, Drug --- Industries, Pharmaceutical --- Pharmaceutic Industries --- Pharmaceutic Industry --- Pharmaceutical Industries --- Accessibility, Health Services --- Contraceptive Availability --- Health Services Geographic Accessibility --- Program Accessibility --- Access to Health Care --- Accessibility of Health Services --- Availability of Health Services --- Accessibility, Program --- Availability, Contraceptive --- Health Services Availability --- Chemical Actions --- Actions, Chemical --- Actions, Pharmacologic --- General Social Development and Population --- Healthcare Economics and Organizations --- Therapeutic Effects --- Effects, Therapeutic --- Uses, Therapeutic --- Anti-Microbial Agents --- Antiinfective Agents --- Antimicrobial Agents --- Microbicides --- Agents, Anti-Infective --- Agents, Anti-Microbial --- Agents, Antiinfective --- Agents, Antimicrobial --- Anti Infective Agents --- Anti Microbial Agents --- Community-Based Distribution --- Contraceptive Distribution --- Delivery of Healthcare --- Dental Care Delivery --- Distribution, Non-Clinical --- Distribution, Nonclinical --- Distributional Activities --- Healthcare --- Healthcare Delivery --- Healthcare Systems --- Non-Clinical Distribution --- Nonclinical Distribution --- Delivery of Dental Care --- Health Care Delivery --- Health Care Systems --- Activities, Distributional --- Activity, Distributional --- Care, Health --- Community Based Distribution --- Community-Based Distributions --- Contraceptive Distributions --- Deliveries, Healthcare --- Delivery, Dental Care --- Delivery, Health Care --- Delivery, Healthcare --- Distribution, Community-Based --- Distribution, Contraceptive --- Distribution, Non Clinical --- Distributional Activity --- Distributions, Community-Based --- Distributions, Contraceptive --- Distributions, Non-Clinical --- Distributions, Nonclinical --- Health Care System --- Healthcare Deliveries --- Healthcare System --- Non Clinical Distribution --- Non-Clinical Distributions --- Nonclinical Distributions --- System, Health Care --- System, Healthcare --- Systems, Health Care --- Systems, Healthcare --- Science, Social --- Sciences, Social --- Social Science --- Administration, Health Services --- Health Services --- Regulation --- Social Control --- Control, Social --- Controls, Social --- Formal Social Control --- Formal Social Controls --- Regulations --- Social Controls --- Healthcare Quality, Access, and Evaluation --- Constitutional Law --- Court Decision --- Law --- Legal Aspects --- Legal Obligations --- Legal Status --- State Interest --- Litigation --- Medical Jurisprudence --- Aspect, Legal --- Aspects, Legal --- Constitutional Laws --- Court Decisions --- Decision, Court --- Decisions, Court --- Interest, State --- Interests, State --- Jurisprudence, Medical --- Law, Constitutional --- Laws --- Laws, Constitutional --- Legal Aspect --- Legal Obligation --- Litigations --- Obligation, Legal --- Obligations, Legal --- State Interests --- Status, Legal --- Antiviral Drugs --- Antivirals --- Agents, Antiviral --- Drugs, Antiviral --- Care Management, Patient --- Management, Patient Care --- Tertiary Sector --- Industries --- Sector, Tertiary --- Sectors, Tertiary --- Tertiary Sectors --- Intellectual Properties --- Properties, Intellectual --- Property, Intellectual --- Antiretroviral Agents --- Agents, Anti-Retroviral --- Agents, Antiretroviral --- Anti Retroviral Agents --- Anti-retroviral agents --- Antiretroviral drugs --- Antiretrovirals --- organization & administration --- Antiretroviral Therapy, Highly Active --- Medically Underserved Area --- Pharmacological and Toxicological Phenomena --- Drug Therapy --- Infection --- Parasites --- Public Policy --- Defamation --- Lawyers --- Interferon Inducers --- Virus Diseases --- Viruses --- Virus Inactivation --- Commerce --- Ethics, Business --- Ownership --- Inventions --- Antiviral agents --- Infections --- Access To Medicines --- Access to Contraception --- Access to Health Services --- Access to Medications --- Access to Therapy --- Access to Treatment --- Contraception Access --- Contraceptive Access --- Medication Access --- Access To Medicine --- Access to Contraceptions --- Access to Medication --- Access to Therapies --- Access to Treatments --- Access, Contraception --- Access, Contraceptive --- Access, Medication --- Contraception, Access to --- Contraceptive Accesses --- Medication Accesses --- Medication, Access to --- Therapy, Access to --- Treatment, Access to --- Health Care Economics --- Health Economics --- Healthcare Economics --- Care Economic, Health --- Economic, Health --- Economic, Health Care --- Economic, Healthcare --- Economics, Health Care --- Health Care Economic --- Health Economic --- Healthcare Economic --- Therapeutic Effect --- Therapeutic Use --- Effect, Therapeutic --- Use, Therapeutic --- Anti-Infective Agent --- Anti-Microbial Agent --- Antimicrobial Agent --- Microbicide --- Agent, Anti-Infective --- Agent, Anti-Microbial --- Agent, Antimicrobial --- Anti Infective Agent --- Anti Microbial Agent --- Antiviral --- Antiviral Agent --- Antiviral Drug --- Agent, Antiviral --- Drug, Antiviral --- Subsaharan Africa --- Africa, Sub-Saharan --- Sub-Saharan Africa --- Access To Care, Health --- Access to Care --- Access to Medicines --- Access to Cares --- Access to Medicine --- Care, Access to --- Cares, Access to --- Medicine, Access to --- Medicines, Access to --- Accessibilities, Health Services --- Agreement on Trade-Related Aspects of Intellectual Property Rights