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This proceedings volume contains a selection of papers presented at the Third International Conference on High Performance Scientific Computing held at the Hanoi Institute of Mathematics, Vietnamese Academy of Science and Technology (VAST), March 6-10, 2006. The conference has been organized by the Hanoi Institute of Mathematics, Interdisciplinary Center for Scientific Computing (IWR), Heidelberg, and its International PhD Program ``Complex Processes: Modeling, Simulation and Optimization'', and Ho Chi Minh City University of Technology. The contributions cover the broad interdisciplinary spectrum of scientific computing and present recent advances in theory, development of methods, and applications in practice. Subjects covered are mathematical modelling, numerical simulation, methods for optimization and control, parallel computing, software development, applications of scientific computing in physics, chemistry, biology and mechanics, environmental and hydrology problems, transport, logistics and site location, communication networks, production scheduling, industrial and commercial problems.

High performance computing --- Science --- Mathematical models. --- Data processing --- Models, Mathematical --- Simulation methods --- Computer science. --- Mathematical optimization. --- Engineering mathematics. --- Computational Science and Engineering. --- Mathematical Modeling and Industrial Mathematics. --- Optimization. --- Theoretical, Mathematical and Computational Physics. --- Mathematical and Computational Engineering. --- Engineering --- Engineering analysis --- Mathematical analysis --- Optimization (Mathematics) --- Optimization techniques --- Optimization theory --- Systems optimization --- Maxima and minima --- Operations research --- System analysis --- Informatics --- Mathematics --- Computer mathematics. --- Mathematical physics. --- Applied mathematics. --- Physical mathematics --- Physics --- Computer mathematics --- Electronic data processing