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"The Networking of Chaperones by Co-chaperones" updates the current understanding of how chaperones are regulated and networked, and is a resource for those in the specialized field of cell stress and chaperones. The book will also be of interest to those in broader cross-cutting field such as cellular networks and systems biology.
Life Sciences. --- Cell Biology. --- Medical Microbiology. --- Life sciences. --- Microbiology. --- Cytology. --- Sciences de la vie --- Microbiologie --- Cytologie --- Electronic books. -- local. --- Molecular chaperones. --- Proteins. --- Molecular chaperones --- Biophysical Processes --- Biochemical Processes --- Proteins --- Biophysical Phenomena --- Physical Processes --- Biochemical Phenomena --- Chemical Processes --- Amino Acids, Peptides, and Proteins --- Protein Folding --- Molecular Chaperones --- Physical Phenomena --- Chemical Phenomena --- Chemicals and Drugs --- Phenomena and Processes --- Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Animal Biochemistry --- Cytology --- Proteids --- Chaperone proteins --- Chaperones, Molecular --- Chaperonins --- Medical microbiology. --- Cell biology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biosciences --- Sciences, Life --- Science --- Biomolecules --- Polypeptides --- Proteomics --- Microbial biology --- Microorganisms
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We are extremely happy to present the reader this book containing a summary of a well-known research field, the phenomenon of cellular stress defense from two new angles: networks and membranes. The volume starts with an introduction to the concept of molecular chaperones in their original sense: R. John Ellis, the founder of the chaperone concept describes chaperones as mediators of correct assembly and/or misassembly of other macromolecular complexes. This sets the tone of the book, where later chapters give detailed examples of the richness of chaperone ac tion by hundreds of other proteins and membrane structures. The reader will learn the role of chaperone classes such as Hsp27 or Hsp90, the action of highly organized chaperone networks in various cellular compartments such as the ER or mitochondrial/ER networks as well as the molecular details of the signaling mechanisms leading to chaperone induction during stress. Various special stress defense mechanisms against oxidative stress or dryness will also be covered. Membranes comprise a surprising mixture of stability and dynamics in the cell. Their role in the regulation of the stress response has been accepted only slowly in the field. Two chapters summarize this important aspect of the stress response showing the importance of membrane hyperstructures, lipid species composition, protein/ membrane interactions and cold adaptation.
Stress (Physiology) --- Molecular chaperones. --- Protein folding. --- Heat shock proteins. --- Stress proteins --- Proteins --- Folding of proteins --- Chaperone proteins --- Chaperones, Molecular --- Chaperonins --- Physiological stress --- Tension (Physiology) --- Adaptation (Biology) --- Folding --- Conformation --- Biochemistry. --- Cytology. --- Immunology. --- Biochemistry, general. --- Cell Biology. --- Biological and Medical Physics, Biophysics. --- Immunobiology --- Life sciences --- Serology --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Composition --- Cell biology. --- Biophysics. --- Biological physics. --- Biological physics --- Physics
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This comprehensive volume, written by experts in the field, provides a current understanding of the molecular properties of the heat shock proteins and their roles in health and disease. Cell Stress Proteins includes advances in several aspects of stress protein research, with chapters ranging from basic studies of the role of heat shock proteins in protein folding to reviews examining the breakdown of stress protein regulation during disease. It also provides analysis of the biochemical and molecular properties of heat shock proteins which can be utilized in evaluating their role in human physiology and pathology. Cell Stress Proteins is an ideal book for researchers, clinicians, physicians, and graduate students in the fields of biochemistry, cell biology, microbiology, immunology, and genetics.
Life Sciences. --- Microbiology. --- Immunology. --- Biochemistry, general. --- Life sciences. --- Biochemistry. --- Sciences de la vie --- Immunologie --- Biochimie --- Microbiologie --- Heat shock proteins. --- Heat shock proteins --- Molecular Chaperones --- Heat-Shock Proteins --- Proteins --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Animal Biochemistry --- Microbiology & Immunology --- Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Stress proteins --- Proteins. --- Protein Science. --- Microbial biology --- Microorganisms --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Immunobiology --- Life sciences --- Serology --- Biosciences --- Sciences, Life --- Science --- Composition --- Proteins .
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