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**Comparative Genomics, Volume 2**, provides a collection of robust protocols for molecular biologists beginning to use comparative genomic analysis tools in a variety of areas. Volume 2 contains the last three of seven sections. In the second volume, the fifth section describes a number of tools for comparative analysis of domain and gene families. These tools are particularly useful for predicting protein function as well as potential protein-protein interactions. In the sixth section, methods for comparing groups of genes and gene order are discussed, as are several tools for analyzing genome evolution. Finally, the seventh section deals with experimental comparative genomics. This section includes methods for comparing gene copy number across an entire genome, comparative genomic hybridization, SNP analysis, as well as genome-wide mapping and typing systems for bacterial genomes.

Molecular biology --- genomics

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The Human Genome Project has spawned a Renaissance of research faced with the daunting expectation of personalized medicine for individuals with sickle cell disease in the Genome Era. This book offers a comprehensive and timeless account of emerging concepts in clinical and basic science research, and community concerns of health disparity to educate professionals, students and the general public about meeting this challenging expectation. Contributions from physicians, research scientists, scientific administrators and community workers make Renaissance of Sickle Cell Disease Research in the

Sickle cell anemia. --- Genomics.

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Molecular biology --- Genetics --- Genomics --- Genomics. --- Genetica --- Moleculaire biologie

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Aging has long been ascribed to the gradual accumulation of mutations in the genome. However, it is only recently that the necessary sophisticated technology has been developed to begin testing this theory and its consequences. This book reviews the concept of genomic instability as a possible universal cause of aging in complex organisms resulting from recent advances in functional genomics and systems biology. - ;Aging has long since been ascribed to the gradual accumulation of DNA mutations in the genome of somatic cells. However, it is only recently that the necessary sophisticated technol

Aging --- Genomes. --- Genetics --- Genomics --- Haploidy --- Genetic aspects.

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Genetics --- Genetics. --- Biology --- Embryology --- Mendel's law --- Adaptation (Biology) --- Breeding --- Chromosomes --- Heredity --- Mutation (Biology) --- Variation (Biology) --- Genomics --- Genetic Structures --- Genetic Phenomena --- Human Genome Project --- Genome --- Comparative Genomics --- Comparative Genomic --- Genomic, Comparative --- Genomics, Comparative --- Genomics. --- Life Sciences --- Human genetics --- genomics