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Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.

Immunology. Immunopathology --- immunologie --- vaccinatie

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Mass immunization is the blitzkrieg of vaccination practice. It serves to rapidly protect populations, both because of the high coverage achieved and because of the herd immunity thereby induced. However, as in war, mass immunization campaigns must be conducted intelligently, with careful strategy and strong attention to logistics of supply and deployment. If conducted badly, mass immunization may fail or even be counter-productive. In this volume, some of the most successful practitioners of mass im- nization tell us about its art and science. David Heymann and Bruce Aylward of WHO begin the book with a theoretical and practical overview of mass immunization. Michael Lane, who participated in the successful effort to eradicate smallpox relates how this was done using mass vaccination and other strategies. Application of mass immunization by the US military is c- ered by John Grabenstein and Remington Nevin, who have a large experience in these matters. Karen Noakes and David Salisbury recount the striking s- cesses of mass immunization in the United Kingdom. The global control of the clostridia that produce diphtheria toxin is described by Charles Vitek. Hepa- tis A is decreasing dramatically under the impact of large-scale vaccination, as Francis André illustrates. The French experience with Hepatitis B vac- nation has been mixed, and François Denis and Daniel Levy-Bruhl explain the circumstances. In?uenza vaccination is an annual example of large-scale campaigns, the complexity of which is recounted by Benjamin Schwartz and Pascale Wortley.

Immunology. Immunopathology --- immunologie --- vaccinatie

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L'impact de l'infection à papillomavirus (HPV) est considérable. Plus d'une femme sur deux a été exposée aux HPV durant sa vie et 10 % environ feront une infection chronique. Parmi elles, 20 % développeront un cancer du col en l'absence ou par défaillance du dépistage. En France, l'infection à HPV à risque provoque 80 000 lésions précancéreuses, 3 400 cancers du col utérin et le décès de 1 000 femmes tous les ans. Le dépistage par frottis réalisé à un rythme régulier et selon des normes de qualité a entraîné une diminution significative de l'incidence et de la mortalité ces vingt dernières années. Cependant, malgré ce succès considérable, la maladie réputée évitable n'a pas été éradiquée; le dépistage est un processus complexe qui ne profite qu'à une partie de la population alors que ceux qui en bénéficient endurent ses faiblesses. L'optimisation du dépistage et de la prise en charge est aujourd'hui rendue possible par l'utilisation de techniques innovantes dans lesquelles s'inscrivent le frottis en suspension liquide, le test HPV, et bientôt le génotypage viral et les marqueurs moléculaires garantissant une protection maximum. Parce que le cancer du col utérin est la conséquence de l'infection chronique à HPV on dispose déjà de l'extraordinaire chance de le prévenir par un vaccin prophylactique. Ce progrès aura un impact majeur sur nos pratiques alors qu'il arrive dans un environnement médico-sociologique peu préparé. Cet ouvrage résolument pratique et didactique dresse un état des lieux des connaissances et des perspectives sur l'infection à HPV et ses pathologies associées tout en décryptant les nouveaux enjeux et les pratiques à l'ère vaccinale.

Oncology. Neoplasms --- Epidemiology --- Gynaecology. Obstetrics --- oncologie --- gynaecologie --- epidemiologie --- vaccinatie --- vroedkunde

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The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences. * Current and thorough 30 chapter reference reviewed by luminaries in the field * Unique single voice' ensures consistency of definitions and concepts * Comprehensive and elegant illustrations bring key concepts to life * Provides historical context to allow fuller understanding of key issues * Introductory chapters 1-4 serve as an Immunology Primer' before topics are discussed in more detail * Includes a CD-ROM containing all the figures and plates appearing in the book.

Immunology. Immunopathology --- immunologie --- HIV infecties --- tumoren --- allergieën --- vaccinatie

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The Immune Response is a unique reference work covering the basic and clinical principles of immunology in a modern and comprehensive fashion. Written in an engaging conversational style, the book conveys the broad scope and fascinating appeal of immunology. The book is beautifully illustrated with superb figures as well as many full color plates. This extraordinary work will be an invaluable resource for lecturers and graduate students in immunology, as well as a vital reference for research scientists and clinicians studying related areas in the life and medical sciences.* Cur

Immunology. Immunopathology --- immunologie --- HIV infecties --- tumoren --- allergieën --- vaccinatie --- Immunology. --- Immunity. --- Immunology --- Immunobiology --- Life sciences --- Serology --- Immunologie --- Immunité --- Immune System Diseases. --- Immune System. --- Immune System Diseases --- Immune System