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Living organisms are open thermodynamic systems whose functional structure has developed and been kinetically frozen during the historical process of biological evolution. A thermodynamics of both nonequilibrium and complex systems is needed for their description. In this book, the foundations of such a thermodynamics are presented. Biological processes at the cellular level are considered as coupled chemical reactions and transport processes across internal and the cytoplasmic membrane. All these processes are catalyzed by specific enzymes hence the kinetics of enzymatic catalysis and its control are described here in detail. The coupling of several processes through a common enzyme is considered in the context of free energy or signal transduction. Special attention is paid to evidence for a rich stochastic internal dynamics of native proteins and its possible role in the control of enzyme activity and in the action of biological molecular machines.
Thermodynamics. --- Biophysics. --- Physics. --- Organic chemistry. --- Biochemistry. --- Cell biology. --- Biological physics. --- Biophysics and Biological Physics. --- Organic Chemistry. --- Cell Biology. --- Biochemistry, general. --- Biological physics --- Biology --- Medical sciences --- Physics --- Chemistry, Physical and theoretical --- Dynamics --- Mechanics --- Heat --- Heat-engines --- Quantum theory --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Organic chemistry --- Natural philosophy --- Philosophy, Natural --- Physical sciences --- Composition --- Chemistry, Organic. --- Cytology. --- Biological and Medical Physics, Biophysics. --- Biophysics --- Thermodynamics --- 577.32 --- 577.32 Molecular biophysics --- Molecular biophysics
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This book provides a review of image analysis techniques as they are applied in the field of diagnostic and therapeutic nuclear medicine. Driven in part by the remarkable sophistication of nuclear medicine instrumentation and - crease in computing power and its ready and inexpensive availability, this is a relatively new yet rapidly expanding field. Likewise, although the use of nuclear imaging for diagnosis and therapy has origins dating back almost to the pioneering work of Dr G. de Hevesy, quantitative imaging has only recently emerged as a promising approach for diagnosis and therapy of many diseases. An effort has, therefore, been made to place the reviews provided in this book in a broader context. The effort to do this is reflected by the inclusion of introductory chapters that address basic principles of nuclear medicine instrumentation and dual-modality imaging, followed by overview of issues that are closely related to quantitative nuclear imaging and its potential role in diagnostic and therapeutic applications. A brief overview of each chapter is provided below. Chapter 1 presents a general overview of nuclear medicine imaging physics and instrumentation including planar scintigraphy, single-photon emission computed tomography (SPECT) and positron emission tomography (PET). Nowadays, patients’ diagnosis and therapy is rarely done without the use of imaging technology. As such, imaging considerations are incorporated in almost every chapter of the book. The development of dual-modality - aging systems is an emerging research field, which is addressed in chapter 2.
Radioisotope scanning --- Image processing --- Data processing. --- Digital techniques. --- Digital image processing --- Radioisotope scintigraphy --- Radionuclide imaging --- Scintigraphy, Radioisotope --- Physics. --- Neurosciences. --- Pharmacology. --- Cardiology. --- Oncology. --- Biophysics. --- Biological physics. --- Biomedical engineering. --- Biophysics and Biological Physics. --- Pharmacology/Toxicology. --- Biomedical Engineering. --- Digital electronics --- Diagnostic imaging --- Radioactive tracers --- Radioactivity --- Radioisotopes in medical diagnosis --- Scanning systems --- Measurement --- Toxicology. --- Oncology . --- Biological and Medical Physics, Biophysics. --- Biomedical Engineering and Bioengineering. --- Tumors --- Heart --- Internal medicine --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Nervous system --- Diseases --- Toxicology --- Drug effects --- Medical pharmacology --- Chemotherapy --- Drugs --- Pharmacy --- Biological physics --- Biology --- Physics --- Physiological effect --- Diagnostic imaging.
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The series Essentials in Ophthalmology was initiated to discuss clinically relevant and appropriate topics two years ago to expedite the timely transfer. Summaries of clinically relevant information of new information in vision science and have been provided throughout each chapter. evidence-based medicine into clinical practice. Each subspecialty area now has been covered We thought that this prospicient idea would be once, and the response to the first eight volumes moved and guided by a resolute commitment in the series has been enthusiastically positive. to excellence. It is reasonable to now update our With the start of the second cycle of subspecialty readers with what has been achieved. coverage, the dissemination of practical information the immediate goal was to transfer information will be continued as we learn more about through a high quality quarterly publication the emerging advances in various ophthalmic in which ophthalmology would be represented by subspecialties that can be applied to obtain the eight subspecialties. In this regard, each issue has best possible care of our patients. Moreover, we had a subspecialty theme and has been overseen will continue to highlight clinically relevant - by two internationally recognized volume editors formation and maintain our commitment to, who in turn have invited a bevy of experts excellence. G. K. Krieglstein R. N.
Glaucoma. --- Glaucoma --- Ocular Hypertension --- Eye Diseases --- Diseases --- Medicine --- Health & Biological Sciences --- Ophthalmology & Optometry --- Eye --- Diseases. --- Medicine. --- Science. --- Nursing. --- Ophthalmology. --- Biophysics. --- Biological physics. --- Medicine & Public Health. --- Medicine/Public Health, general. --- Science, general. --- Biophysics and Biological Physics. --- Ophthalmology --- High intraocular pressure --- Intraocular pressure, High --- Diseases and defects --- Science, Humanities and Social Sciences, multidisciplinary. --- Biological and Medical Physics, Biophysics. --- Clinical nursing --- Nurses and nursing --- Nursing process --- Care of the sick --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Health Workforce --- Biological physics --- Biology --- Physics
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Nano-science and nano-technology are rapidly developing scientific and technological areas that deal with physical, chemical and biological processes that occur on nano-meter scale – one millionth of a millimeter. Self-organization and pattern formation play crucial role on nano-scales and promise new, effective routes to control various nano-scales processes. This book contains lecture notes written by the lecturers of the NATO Advanced Study Institute "Self-Assembly, Pattern Formation and Growth Phenomena in Nano-Systems" that took place in St Etienne de Tinee, France, in the fall 2004. They give examples of self-organization phenomena on micro- and nano-scale as well as examples of the interplay between phenomena on nano- and macro-scales leading to complex behavior in various physical, chemical and biological systems. They discuss such fascinating nano-scale self-organization phenomena as self-assembly of quantum dots in thin solid films, pattern formation in liquid crystals caused by light, self-organization of micro-tubules and molecular motors, as well as basic physical and chemical phenomena that lead to self-assembly of the most important molecule on the basis of which most of living organisms are built – DNA. A review of general features of all pattern forming systems is also given. The authors of these lecture notes are the leading experts in the field of self-organization, pattern formation and nonlinear dynamics in non-equilibrium, complex systems.
Natuurwetenschappen --- Physical sciences --- Sciences physiques --- Pattern formation (Physical sciences) --- Nanoscience. --- Formation des structures (Sciences physiques) --- Nanosciences --- Pattern formation (Physical sciences). --- Nanoscience --- Physical Sciences & Mathematics --- Sciences - General --- EPUB-LIV-FT Growth LIVPHYSI Nano-systems SPRINGER-B phenomena --- Nano science --- Nanoscale science --- Physics. --- Amorphous substances. --- Complex fluids. --- Biophysics. --- Biological physics. --- Statistical physics. --- Dynamical systems. --- Statistical Physics, Dynamical Systems and Complexity. --- Soft and Granular Matter, Complex Fluids and Microfluidics. --- Biophysics and Biological Physics. --- Dynamical systems --- Kinetics --- Mathematics --- Mechanics, Analytic --- Force and energy --- Mechanics --- Physics --- Statics --- Mathematical statistics --- Biological physics --- Biology --- Medical sciences --- Complex liquids --- Fluids, Complex --- Amorphous substances --- Liquids --- Soft condensed matter --- Natural philosophy --- Philosophy, Natural --- Dynamics --- Statistical methods --- Growth phenomena --- Nano-systems
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Biological membranes have long been identified as key elements in a wide variety of cellular processes including cell defense communication, photosynthesis, signal transduction, and motility; thus they emerge as primary targets in both basic and applied research. This book brings together in a single volume the most recent views of experts in the area of protein–lipid interactions, providing an overview of the advances that have been achieved in the field in recent years, from very basic aspects to specialized technological applications. Topics include the application of X-ray and neutron diffraction, infrared and fluorescence spectroscopy, and high-resolution NMR to the understanding of the specific interactions between lipids and proteins within biological membranes, their structural relationships, and the implications for the biological functions that they mediate. Also covered in this volume are the insertion of proteins and peptides into the membrane and the concomitant formation of definite lipid domains within the membrane.
Membrane lipids. --- Membrane proteins. --- Protein binding. --- Lipoproteins. --- Lipides membranaires --- Protéines membranaires --- Protéines --- Lipoprotéines --- Fixation --- Biophysics --- Animal Biochemistry --- Biology --- Human Anatomy & Physiology --- Health & Biological Sciences --- Lipids. --- Proteins. --- Protéines membranaires --- Protéines --- Lipoprotéines --- EPUB-LIV-FT LIVPHYSI SPRINGER-B --- Binding, Protein --- Proteids --- Lipides --- Lipins --- Lipoids --- Physics. --- Bioorganic chemistry. --- Biochemistry. --- Cell biology. --- Biophysics. --- Biological physics. --- Biophysics and Biological Physics. --- Biochemistry, general. --- Cell Biology. --- Bioorganic Chemistry. --- Membranes (Biology) --- Lipids --- Biomolecules --- Polypeptides --- Proteomics --- Steroids --- Proteins --- Biochemistry --- Allosteric proteins --- Radioligand assay --- Cytology. --- Biological and Medical Physics, Biophysics. --- Bio-organic chemistry --- Biological organic chemistry --- Chemistry, Organic --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Composition --- Biological physics --- Physics
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Technical advancements are basic elements in our life. In biophysical studies, new applications and improvements in well-established techniques are being implemented every day. This book deals with advancements produced not only from a technical point of view, but also from new approaches that are being taken in the study of biophysical samples, such as nanotechniques or single-cell measurements. This book constitutes a privileged observatory for reviewing novel applications of biophysical techniques that can help the reader enter an area where the technology is progressing quickly and where a comprehensive explanation is not always to be found.
Biophysics. --- Biophysique --- Biophysics -- Technique. --- Biophysics --- Biological Science Disciplines --- Physics --- Natural Science Disciplines --- Disciplines and Occupations --- Biology - General --- Biology --- Health & Biological Sciences --- Technique --- Research. --- EPUB-LIV-FT LIVPHYSI SPRINGER-B --- Biological research --- Biomedical research --- Biological physics --- Physics. --- Biotechnology. --- Biochemistry. --- Cell biology. --- Biological physics. --- Biophysics and Biological Physics. --- Microengineering. --- Biochemistry, general. --- Biological Techniques. --- Cell Biology. --- Technique. --- Medical sciences --- Microreactors. --- Cytology --- Cytology. --- Biological and Medical Physics, Biophysics. --- Research --- Methodology. --- Cell biology --- Cellular biology --- Cells --- Cytologists --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Micro-chemical engineering --- Microchannel reactors --- Microfabricated reactors --- Microreaction technology --- Mini-scale reactors --- Nano-scale reactors --- Chemical reactors --- Composition --- Biology—Technique. --- Chemical engineering --- Genetic engineering
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Mechanosensing and Mechanochemical Transduction in Extracellular Matrix offers the reader recent information in addition to models of how mechanical information is transduced into genetic and biochemical changes at the cellular and tissue levels. Mechanosensing and Mechanochemical Transduction in Extracellular Matrix is intended to serve as a textbook at the graduate and advanced undergraduate level in a biomedical engineering curriculum. Topics covered include: Structure of Macromolecules That Make Up Tissue Structure Microscopic and Macroscopic Tissue Structures Methods For Analyzing Macromolecular Structure and Physical Properties Self-Assembly of Biological Macromolecules Involved In Mechanotransduction Mechanical Properties of Biological Macromolecules Viscoelastic Properties of Macromolecules and Tissues Models of Mechanical Properties of Tissues Mechanochemical Sensing and Transduction Mechanochemical Transduction and Its Role in Biology Mechanosensing and Mechanochemical Transduction in Extracellular Matrix is essential reading for biomedical engineers, biologists, physicians, health care professionals and other biomedical researchers who are interested in understanding how physical forces affect the biology, physiology and pathophysiology of humans. About the Author: Frederick H. Silver, Ph.D., is an expert on the effect of mechanical forces on extracellular matrix. He has been a faculty member in Biomedical Engineering departments at Boston University, University of Minnesota and Rutgers University. He is currently Professor of Pathology and Laboratory medicine at UMDNJ-Robert Wood Johnson Medical School.
Engineering. --- Biochemical engineering. --- Life sciences. --- Biophysics. --- Biological physics. --- Biomedical engineering. --- Biomedical Engineering. --- Biophysics and Biological Physics. --- Biochemical Engineering. --- Life Sciences, general. --- Extracellular matrix. --- Extracellular matrix --- Cellular signal transduction. --- Cell interaction. --- Mechanical properties. --- Cell-cell interaction --- Cell communication --- Cellular communication (Biology) --- Cellular interaction --- Intercellular communication --- Cellular control mechanisms --- Cellular information transduction --- Information transduction, Cellular --- Signal transduction, Cellular --- Bioenergetics --- Information theory in biology --- Cement substance (Anatomy) --- Ground substance (Anatomy) --- Ground substance (Histology) --- Intercellular matrix --- Interstitial substance --- Matrix, Extracellular --- Connective tissues --- Extracellular space --- Biomedical Engineering and Bioengineering. --- Biological and Medical Physics, Biophysics. --- Biosciences --- Sciences, Life --- Science --- Bio-process engineering --- Bioprocess engineering --- Biochemistry --- Biotechnology --- Chemical engineering --- Clinical engineering --- Medical engineering --- Bioengineering --- Biophysics --- Engineering --- Medicine --- Cell interactions --- Cellular signal transduction --- macromolecule --- mechanochemical --- mechanosensing --- Mechanical properties --- Biological physics --- Biology --- Medical sciences --- Physics
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Principles of Fluorescence Spectroscopy, 3rd edition , 3rd edition Joseph R. Lakowicz The third edition of the established classic text reference, Principles of Fluorescence Spectroscopy, will enhance upon the earlier editions' successes. Organized as a textbook for the learning student or the researcher needing to acquire the core competencies, Principles of Fluorescence Spectroscopy, 3e will maintain the emphasis on basics, while updating the examples to include recent results from the literature. The third edition also includes new chapters on single molecule detection, fluorescence correlation spectroscopy, novel probes and radiative decay engineering. This full-color textbook features the following: Problem sets following every chapter Glossaries of commonly used acronyms and mathematical symbols Appendices containing a list of recommended books which expand on various specialized topics Sections describing advanced topics will indicate as such, to allow these sections to be skipped in an introductory course, allowing the text to be used for classes of different levels Includes CD-ROM of all figures in a low-res format, perfect for use in instruction and presentations Principles of Fluorescence Spectroscopy, 3rd edition, is an essential volume for students, researchers, and industry professionals in biophysics, biochemistry, biotechnology, bioengineering, biology and medicine. About the Author: Dr. Joseph R. Lakowicz is Professor of Biochemistry at the University of Maryland School of Medicine, Baltimore, and Director of the Center for Fluorescence Spectroscopy. Dr. Lakowicz has published over 400 scientific articles, has edited numerous books, holds 16 issued patents, and is the author of the widely used text, Principles of Fluorescence Spectroscopy now in its 3rd edition. .
Theoretical spectroscopy. Spectroscopic techniques --- fysicochemie --- Fluorescence spectroscopy. --- Spectroscopie de fluorescence --- Fluorescence spectroscopy --- Analytical Chemistry --- Chemistry --- Physical Sciences & Mathematics --- Basic Sciences. Biology --- Biological Techniques --- 535.372 --- Fluorescence spectrometry --- Spectrometry, Fluorescence --- Spectroscopy, Fluorescence --- Luminescence spectroscopy --- Fluorescent probes --- Fluorescence spectra --- Biological Techniques. --- 535.372 Fluorescence spectra --- EPUB-LIV-FT LIVCHIMI SPRINGER-B --- Chemistry. --- Analytical chemistry. --- Mass spectrometry. --- Biotechnology. --- Physical chemistry. --- Biochemistry. --- Biophysics. --- Biological physics. --- Mass Spectrometry. --- Analytical Chemistry. --- Biophysics and Biological Physics. --- Biochemistry, general. --- Physical Chemistry. --- Analytical biochemistry. --- Chemistry, Physical organic. --- Biological and Medical Physics, Biophysics. --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Chemical engineering --- Genetic engineering --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Analytic biochemistry --- Biochemistry --- Chemistry, Analytic --- Mass spectra --- Mass spectrograph --- Mass spectroscopy --- Mass spectrum analysis --- Mass (Physics) --- Nuclear spectroscopy --- Spectrum analysis --- Composition --- Bioanalytic chemistry --- Bioanalytical chemistry --- Analytical chemistry --- Biological physics --- Physics --- Analysis, Chemical --- Analytic chemistry --- Chemical analysis --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Chemistry, Physical and theoretical.
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It is with great pleasure that we present this completely revised English e- tion of our book How Does MRI Work? An Introduction to the Physics and Function of Magnetic Resonance Imaging only two years afer publication of the frst English edition. We are particularly pleased that our introductory textbook met with great approval in the English-speaking world and not just in the German-speaking countries. Tis success has been an enormous - centive for us to further improve and update the text. For this reason, we are now presenting a second edition. All chapters have been thoroughly revised and updated to include the latest developments in the ever-changing feld of MRI technology. In particular, the chapter on cardiovascular imaging has been improved and expanded. We gratefully acknowledge the contribution of Daniel Nanz, PhD, the author of this chapter. Moreover, two completely new chapters have been added: “Fat Suppression Techniques” and “High- Field Clinical MR Imaging”. Notwithstanding these additions, the intended readership of our book remains the same: it is not a book for MR specialists or MR physicists but for our students, residents, and technologists, in short, all those who are interested in MRI and are looking for an easy-to-understand introduction to the technical basis of this imaging modality at the beginning of their MRI training. Te second English edition presented here corresponds to and appears together with the completely revised ffh German edition.
Magnetic Resonance Imaging --- Magnetic resonance imaging --- Imagerie par résonance magnétique --- 608.5 --- Medische beeldvorming --- MRI --- Radiologie --- Magnetic resonance imaging. --- Magnetic Resonance Imaging. --- Diagnostic Imaging --- Tomography --- Diagnostic Techniques and Procedures --- Diagnosis --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Physics --- Medicine --- Physical Sciences & Mathematics --- Health & Biological Sciences --- Electricity & Magnetism --- Radiology, MRI, Ultrasonography & Medical Physics --- Clinical magnetic resonance imaging --- Diagnostic magnetic resonance imaging --- Functional magnetic resonance imaging --- Imaging, Magnetic resonance --- Medical magnetic resonance imaging --- MR imaging --- MRI (Magnetic resonance imaging) --- NMR imaging --- Nuclear magnetic resonance --- Nuclear magnetic resonance imaging --- Diagnostic use --- Medicine. --- Radiology. --- Condensed matter. --- Biophysics. --- Biological physics. --- Medicine & Public Health. --- Imaging / Radiology. --- Condensed Matter Physics. --- Biophysics and Biological Physics. --- Cross-sectional imaging --- Diagnostic imaging --- Radiology, Medical. --- Biological and Medical Physics, Biophysics. --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Biological physics --- Biology --- Medical sciences --- Condensed materials --- Condensed media --- Condensed phase --- Materials, Condensed --- Media, Condensed --- Phase, Condensed --- Liquids --- Matter --- Solids --- Radiological physics --- Radiation
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Provides a description of fundamental aspects of protein adsorption to surfaces, a phenomenon that plays a key role in biotechnological applications, especially at solid-liquid interfaces. This book presents the methods for studying adsorption kinetics and conformational changes such as optical waveguide lightmode spectroscopy (OWLS).
Adsorption --- Proteins --- Solid-liquid interfaces --- Protéines --- Interfaces solide-liquide --- Adsorption. --- Proteins. --- Solid-liquid interfaces. --- Amino Acids, Peptides, and Proteins --- Molecular Conformation --- Chemical Processes --- Physicochemical Processes --- Metabolism --- Chemical Phenomena --- Molecular Structure --- Physicochemical Phenomena --- Chemicals and Drugs --- Metabolic Phenomena --- Phenomena and Processes --- Biochemical Phenomena --- Protein Conformation --- Absorption --- Mechanical Engineering --- Chemical & Materials Engineering --- Engineering & Applied Sciences --- Bioengineering --- Chemical Engineering --- Protéines --- EPUB-LIV-FT LIVCHIMI SPRINGER-B --- Liquid-solid interfaces --- Proteids --- Sorption --- Chemistry. --- Biotechnology. --- Physical chemistry. --- Biochemistry. --- Biophysics. --- Biological physics. --- Materials --- Thin films. --- Biophysics and Biological Physics. --- Physical Chemistry. --- Biochemistry, general. --- Surfaces and Interfaces, Thin Films. --- Surfaces. --- Interfaces (Physical sciences) --- Biomolecules --- Polypeptides --- Proteomics --- Separation (Technology) --- Surface chemistry --- Chemistry, Physical organic. --- Surfaces (Physics). --- Biological and Medical Physics, Biophysics. --- Physics --- Surfaces (Technology) --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Chemical engineering --- Genetic engineering --- Composition --- Materials—Surfaces. --- Films, Thin --- Solid film --- Solid state electronics --- Solids --- Coatings --- Thick films --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Biological physics
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