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A new edition of a book is always warranted when it needs to be updated because of advances in the ?eld over time. Although the basics of physics, instrumentation, and radiobiology have not changed, their tech- logical applications have been changing and improving continually. Nuclear medicine professionals worldwide appreciate the book so much that the previous edition has been published in Japanese. Changes in content and appreciation of the book are the two guiding factors in writing this third edition. Like the previous editions, the book is aimed at residents taking the American Board of Nuclear Medicine, the American Board of Radiology (Physics part), and the American Board of Radiology with Special C- petency in Nuclear Medicine examinations,and for the technologists taking the Nuclear Medicine Technology Certifying Board. The book contains 16 chapters,and at the end of each chapter,references and suggested readings have been updated and new questions have been added where appropriate. The ?rst 10 chapters have only minor changes because of the basic nature of the contents. A section on the chi-square test and evaluation of diagnostic tests has been added in Chapter 4. Additional radionuclides have been included in Table 5. 1. In Chapter 8, the section on scintillation detectors has been rearranged and the section on dead time has been expanded. In Chapter 10, the sections on uniformity, gamma camera tuning, and quality control tests have been revised. A new section on software and DICOM has been added in Chapter 11.

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