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Reoviridae family members are large, complex viruses that infect human, animals, plants and insects. They are unique in that they lack lipid envelopes and package their genomes of discrete double-stranded segments of RNA within multi-layered capsids. Lack of a lipid envelope has allowed three-dimensional structures of these large complex viruses to be obtained. The capsids of these viruses undergo cell entry, uncoating, the enzymatic functions necessary for transcription of the genome, and are later involved in egress from host cells. Recent years have seen an increase in our knowledge of the structure of these viruses coupled with substantial progress in unravelling the molecular details of these processes. Intriguingly, despite their diversity in hosts, structures and modes of transmission, striking parallels have emerged in the molecular interactions necessary for the essential processes of virus entry, assembly and release. This book reviews our current understanding of Reoviridae entry, disassembly/assembly and egress in addition to updating high resolution structures of viral proteins and capsids from three different genera of the family.
Reoviruses. --- Microbiology. --- Microbial biology --- Biology --- Microorganisms --- Reoviridae --- Respiratory enteric orphan viruses --- RNA viruses --- Medical virology. --- Virology. --- Medical microbiology --- Virology --- Virus diseases --- Microbiology
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Influenza vaccines. --- Influenza viruses. --- Influenza. --- Influenza --- Influenza vaccines --- Influenza viruses --- Orthomyxoviruses --- Influenza virus vaccines --- Viral vaccines --- Flu --- Flu, Respiratory --- Grippe --- Respiratory flu --- Respiratory infections --- Virus diseases --- INFLUENZAVIRUS A --- RNA VIRUSES --- INFLUENZA, HUMAN --- INFLUENZA VACCINES --- METABOLISM --- IMMUNOLOGY --- PATHOGENICITY --- HISTORY
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Computational Biology --- Flaviviridae --- Biochemistry --- Hepatitis Viruses --- Genetics --- Biology --- Biological Science Disciplines --- RNA Viruses --- Chemistry --- Viruses --- Vertebrate Viruses --- Natural Science Disciplines --- Organisms --- Disciplines and Occupations --- Molecular Biology --- Hepacivirus --- Genomics --- Health & Biological Sciences --- Microbiology & Immunology --- Genomics. --- Molecular Biology. --- genetics.
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This booklet describes the outbreak of human cases of avian influenza in Turkey and the national and international response. Drawing on interviews with some of the key health workers and major agencies involved - the European Centre for Disease Prevention and Control (ECDC), the United Nations Children's Fund (UNICEF), the Food and Agriculture Organization of the United Nations (FAO) and the World Organisation for Animal Health (OIE), as well as WHO - it points out practical lessons that national and international public health agencies and policy-makers can use to respond effectively to futur
Avian influenza. --- Avian influenza --- Avian influenza --- Influenza in Birds --- Disease Outbreaks --- Influenza, Human --- Influenza A virus --- Alphainfluenzavirus. --- Orthomyxoviridae Infections --- Public Health --- Bird Diseases --- Poultry Diseases --- Respiratory Tract Infections --- Animal Diseases --- RNA Virus Infections --- Environment and Public Health --- Orthomyxoviridae --- Respiratory Tract Diseases --- Disease. --- RNA Viruses --- Virus Diseases --- Delivery of Health Care. --- Viruses --- Vertebrate Viruses --- Organisms --- Prevention
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This book summarizes the keynote and plenary speeches and posters of the Xth International Nidovirus Symposium: Toward Control of SARS and Other Nidovirus Diseases” that was held in Colorado Springs, Colorado, June 25–30, 2005. The nine previous meetings of scientists investigating the molecular biology and pathogenesis of coronaviruses, toroviruses, arteriviruses, and okaviruses were generally held every 3 years since the first meeting was convened in Wurzburg, Germany, in October, 1980. The Xth International Symposium was held just 2 years after the IXth International Symposium (Nido2003) in The Netherlands, because of the tremendously increased research on nidoviruses that resulted from the discovery that the global epidemic of severe acute res- ratory syndrome (SARS) in 2002–2003 was caused by a newly discovered coronavirus called SARS-CoV. A record 225 scientists from 14 countries attended the Xth International Nidovirus Symposium, and important advances in every aspect of nidovirus molecular biology and pathogenesis were reported and discussed. The meeting was divided into 12 sessions, with keynote speakers providing a general review of research pertinent to each one. This volume is a collection of scientific papers presented at the symposium. Once a coronavirus was recognized as the etiological agent of SARS, intensive work by many investigators resulted in determination of the sequence of the virus, engineering of reverse genetics systems, and identification of the host cell receptor used by the virus. With the increased interest in coronaviruses, new members of the family associated with human disease were identified.
RNA viruses --- Medicine, Preventive --- SARS (Disease) --- Nidoviruses --- Nidovirales --- Acute respiratory syndrome, Severe --- Respiratory syndrome, Severe acute --- Severe acute respiratory syndrome --- Coronavirus infections --- Respiratory infections --- Syndromes --- Riboviruses --- Viruses, RNA --- Viruses --- Immunology. --- Emerging infectious diseases. --- Microbiology. --- Epidemiology. --- Medical virology. --- Pathology. --- Infectious Diseases. --- Virology. --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medical microbiology --- Virology --- Virus diseases --- Public health --- Microbial biology --- Biology --- Microorganisms --- Emerging infections --- New infectious diseases --- Re-emerging infectious diseases --- Reemerging infectious diseases --- Communicable diseases --- Immunobiology --- Life sciences --- Serology --- Infectious diseases. --- Microbiology --- Communicable diseases. --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Infection --- Epidemics
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Where did this frightening disease come from? How did it spread? And will the world be any better prepared if it returns? For the first time, these and other questions are answered in this remarkable inside account of what really took place in those fateful months of 2003 when severe acute respiratory syndrome threatened to engulf the world.
Communicable diseases -- Prevention. --- Communicable Diseases, Emerging. --- Communicable diseases. --- Epidemics -- Prevention. --- Public health -- United States. --- SARS (Disease) -- Epidemiology. --- SARS (Disease) -- Prevention -- Government policy -- United States. --- SARS (Disease) -- Research -- United States. --- Severe acute respiratory syndrome-related coronavirus. --- Severe Acute Respiratory Syndrome --- Disease Outbreaks --- Communicable Diseases, Emerging --- Coronavirus Infections --- Coronavirus --- Public Health --- Respiratory Tract Infections --- Communicable Diseases --- Coronaviridae Infections --- Coronaviridae --- Respiratory Tract Diseases --- Environment and Public Health --- Infections. --- Disease. --- Nidovirales Infections --- Nidovirales --- Delivery of Health Care. --- Bacterial Infections and Mycoses --- RNA Viruses --- RNA Virus Infections --- Vertebrate Viruses --- Viruses --- Virus Diseases --- Organisms
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Multiplication is the basic biological function of all organisms and is dependent upon replication of genomes. This is also true of plant viruses even though they possess a minimum of essential genetic information. Phylogenetically, replication-associated genes constitute the core elements of RNA virus genomes while other gene modules are considered as accessory elements. However, the biochemical studies on plant virus RNA replication were in their infancy even in 1999-2000. The picture has improved much since structural and sequence requirements of viral RNA replication, and synthesis are beginning to be understood, primarily because of the genetic, molecular, biochemical, and enzymatic studies conducted during the last six years. Certain virus-encoded essential proteins, nucleotide sequence motifs, and RNA secondary structures are central to virus RNA replication, which has a number of stages. Each stage is a complex phenomenon requiring specific factors and conditions. All this has generated much new information so that replication of plus-sense RNA plant viruses has now emerged as a rapidly developing field. However a lot of distance still has to be covered and traversing this distance could prove difficult because no one organised corpus of knowledge is available. Hopefully, this book fills the niche and generates understanding of multiplication of plus-sense RNA plant viruses, especially at molecular level. Nearly all the information on various aspects of plant virus multiplication has been collected, collated, and organized in eleven chapters spanning 332 pages so that this book comprehensively covers all facets of multiplication of plus-sense RNA plant viruses. No such book has been published so far.
Plant viruses --- RNA viruses. --- Genetics. --- Viral genetics --- Riboviruses --- Viruses, RNA --- Viruses --- Plant diseases. --- Plant genetics. --- Biochemistry. --- Botany. --- Plant Pathology. --- Plant Genetics and Genomics. --- Plant Biochemistry. --- Plant Sciences. --- Botanical science --- Phytobiology --- Phytography --- Phytology --- Plant biology --- Plant science --- Biology --- Natural history --- Plants --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Medical sciences --- Genetics --- Botany --- Communicable diseases in plants --- Crop diseases --- Crops --- Diseases of plants --- Microbial diseases in plants --- Pathological botany --- Pathology, Vegetable --- Phytopathology --- Plant pathology --- Vegetable pathology --- Agricultural pests --- Crop losses --- Diseased plants --- Phytopathogenic microorganisms --- Plant pathologists --- Plant quarantine --- Composition --- Pathology --- Diseases and pests --- Diseases --- Wounds and injuries --- Plant pathology. --- Plant biochemistry. --- Plant science. --- Phytochemistry --- Plant biochemistry --- Plant chemistry --- Biochemistry --- Phytochemicals --- Plant biochemical genetics --- Floristic botany
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Anti-Retroviral Agents --- Drug Resistance, Microbial --- Sexually Transmitted Diseases, Viral --- HIV --- Drug Evaluation, Preclinical --- Immunologic Deficiency Syndromes --- Lentivirus Infections --- Virus Physiological Phenomena --- Microbiological Techniques --- Microbiological Phenomena --- Lentiviruses, Primate --- Evaluation Studies as Topic --- Drug Resistance --- Immune System Diseases --- Clinical Laboratory Techniques --- Retroviridae Infections --- Sexually Transmitted Diseases --- Antiviral Agents --- RNA Virus Infections --- Lentivirus --- Anti-Infective Agents --- Investigative Techniques --- Virus Diseases --- Phenomena and Processes --- Pharmacological Phenomena --- Diseases --- Retroviridae --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Physiological Phenomena --- Therapeutic Uses --- Pharmacologic Actions --- RNA Viruses --- Viruses --- Chemical Actions and Uses --- Vertebrate Viruses --- Chemicals and Drugs --- Organisms --- Microbial Sensitivity Tests --- Drug Resistance, Viral --- HIV Infections --- HIV-1 --- Anti-HIV Agents --- Microbial Sensitivity Tests. --- Drug Resistance, Viral. --- drug therapy. --- drug effects. --- pharmacoloogy.
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